Abstracts Archive - Page 75 of 1683 - ATC Abstracts

2022 American Transplant Congress
Hold the Opioids Please: Long-Term Outcomes Following an Opioid Minimization Protocol in Kidney Transplantation
T. Carcella, N. Patel, J. Marable, J. Fleming, P. Baliga, D. Dubay, S. Bethi, D. Taber, V. Rohan
Medical University of South Carolina, Charleston, SC
*Purpose: Opioid use following kidney transplantation (KTX) is associated with an increased risk of graft loss and mortality. Opioid minimization strategies and protocols have demonstrated…
2022 American Transplant Congress
De Novo DSA in the Setting of Stable Allograft Function is a Benign Finding
R. J. Knight, E. A. Graviss, D. T. Nguyen, T. N. Eagar, S. G. Yi, H. Podder, M. Hobeika, R. McMillan, A. O. Gaber
Houston Methodist Hospital, Houston, TX
*Purpose: We sought to determine the long-term outcome of renal allografts that developed de novo DSA (dnDSA) in the setting of stable renal function.*Methods: A…
2022 American Transplant Congress
Leveraging Single-Cell Signatures in Kidney Transplant Biopsies Uncovers Immunological Heterogeneity Within Rejection Phenotypes
J. Callemeyn¹, B. Lamarthée¹, P. Koshy², T. Debyser³, E. Van Loon¹, A. Franken⁴, T. Van Brussel⁴, I. Arijs⁴, D. Lambrechts⁴, M. Rabant⁵, A. Senev¹, T. Vaulet⁶, C. Tinel¹, M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²Department of Morphology and Molecular Pathology, University Hospitals Leuven, Leuven, Belgium, ³Faculty of Medicine, KU Leuven, Leuven, Belgium, ⁴Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium, ⁵Necker-Enfants Malades Institute, Institut national de la santé et de la recherche médicale (Inserm), Université de Paris, Paris, France, ⁶ESAT Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium
*Purpose: Rejection of the kidney allograft is hallmarked by the accumulation of inflammatory cells within the renal architecture, leading to microvascular or tubulointerstitial inflammation. However,…
2022 American Transplant Congress
Associated Factors to Physical Inactivity of Kidney Transplant Patients: Subproject of ADHERE Brazil Multicenter Study
E. S. Sertorio¹, F. A. Colugnati¹, K. Denhaerynck², S. De Smet³, J. O. Medina⁴, M. M. Reboredo⁵, S. De Geest², H. Sanders-Pinheiro¹, T. ADHERE BRAZIL Study team¹
¹Nephrology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, ²Department of Public Health, Institute of Nursing Science, University of Basel, Basel, Switzerland, ³Transplant Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ⁴Nephrology, Hsopital do Rim, Federal University of São Paulo, São Paulo, Brazil, ⁵Pneumology, Federal University of Juiz de Fora, Juiz de Fora, Brazil
*Purpose: Even though regular physical activity is a current recommendation for kidney transplant recipients (KTR), results from ADHERE Brazil study revealed a high prevalence of…
2022 American Transplant Congress
Favorable Outcomes in Older Recipients Receiving Simultaneous Kidney Pancreas Transplantation
P. Budhiraja¹, H. Me¹, J. Ninan², S. Reddy², s. S. Misra¹, R. Heilman¹, H. Khamash¹, K. Reddy¹, C. Jadloweic¹, N. Katariya¹, H. Chakkera¹
¹Mayo Clinic, Phoenix, AZ, ²Mayo Clinic, Rochester, MN
*Purpose: Improved therapeutic advances in diabetes mellitus care have resulted in a higher number of older diabetics on dialysis. The majority of centers use an…
2022 American Transplant Congress
Does a Second Transplant Increase the Risk for CMV Infection? An Evaluation of the Incidence of CMV Viremia in the Previously Transplanted Kidney Recipient
J. Byrns¹, G. Katz-Greenberg²
¹Pharmacy, Duke University Hospital, Durham, NC, ²Medicine, Duke University Medical Center, Durham, NC
*Purpose: Cytomegalovirus (CMV) viremia is a common complication of kidney transplant recipients (KTR) with significant morbidity/mortality. Patients who receive multiple transplants are potentially at a…
2022 American Transplant Congress
Antibody-Mediated Kidney Allograft Rejection (ABMR) Monitoring and Intervention Based on ABMR Subtypes – A Step Towards Precision Diagnosis and Management
A. Rizvi¹, S. Hussain², M. Kueht³, J. Fair³, A. Gamilla-Crudo⁴, M. Mujtaba⁴
¹Internal Medicine, Nephrology, University of Texas Medical Branch, Galveston, TX, ²University of Texas Medical Branch, Houston, TX, ³Surgery, University of Texas Medical Branch, Galveston, TX, ⁴University of Texas Medical Branch, Galveston, TX
*Purpose: The monitoring of kidney allograft for early detection of antibody mediated rejection (ABMR) and subsequent intervention using traditional clinical parameters has been insufficient due…
2022 American Transplant Congress
Clinical Outcomes with IR-tac to LCP-tac Conversion in a Kidney Transplant Population
F. Bartlett¹, J. Newman¹, T. Sprague¹, S. Patel¹, N. Rao², E. Andrade², V. Rohan², M. Casey², D. Dubay¹, D. Taber¹
¹Pharmacy, Medical University of South Carolina, Charleston, SC, ²Medical University of South Carolina, Charleston, SC
*Purpose: LCP-Tac is approved for conversion from IR-Tac in kidney transplant patients with a conversion rate of 70-80%. Studies have demonstrated similar efficacy and safety…
2022 American Transplant Congress
Are Changes in Clinical Practice Reflected in Gene Expression Profiling Scores After Heart Transplantation?
T. Wolf-Doty¹, K. K. Khush², J. J. Teuteberg²
¹CareDx, Brisbane, CA, ²Stanford University, Stanford, CA
*Purpose: AlloMap (AM) is a peripheral blood gene expression profiling (GEP) tool used for the assessment of acute cellular rejection in heart transplant recipients (HT).…
2022 American Transplant Congress
HCK is a Key Regulator for Macrophage Polarization in Kidney Fibrosis
C. Wei, M. Chen, Z. Sun, Z. Yi, C. He, W. Zhang
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Interstitial fibrosis and tubular atrophy (IF/TA) is common histological abnormality in biopsy of kidney transplants. Our previous study from a prospective human kidney transplant…