ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Everolimus in Liver Transplantation for Diffuse, Unresectable Neuroendocrine Tumor

    J. M. Vanatta1, R. A. Helmick2, C. Eymard2, N. Nezakatgoo2, P. Horton2, J. P. Kothadia2, S. P. Nair2, J. D. Eason2

    1Transplantation, University of Tennessee/Methodist University Hospital, Memphis, TN, 2Transplantation, University of Tennessee, Memphis, TN

    *Purpose: Liver transplantation (LT) has emerged as a therapy in selected patients for neuroendocrine tumor (NET) by providing cytoreduction. Progression-free survival in NET has been…
  • 2022 American Transplant Congress

    SARS-CoV-2 Infection is Associated with Greater Neutralizing Antibody Response Compared to Three Doses of Mrna-1273 Vaccine in Solid Organ Transplant Recipients

    V. H. Ferreira, V. Hall, T. M. Marinelli, M. Ierullo, V. Kulasingam, A. Humar, D. Kumar

    University Health Network, Toronto, ON, Canada

    *Purpose: Prior studies suggest that two doses of mRNA vaccine in SOTR may result in lower antibody and T-cell responses relative to levels seen following…
  • 2022 American Transplant Congress

    De Novo Focal Segmental Glomerulosclerosis in the Kidney Allograft: Association with Alloimmunity Leading to Poor Outcome

    J. Leon1, J. Duong Van Huyen2, A. Abderrahmane1, D. Anglicheau1, C. Legendre1, M. Rabant2

    1KIDNEY TRANSPLANTATION, Necker Hospital, Paris, France, 2KIDNEY PATHOLOGY, Necker Hospital, Paris, France

    *Purpose: Focal Segmental Glomerulosclerosis (FSGS) can be found de novo (Dn) or as a recurrence in kidney allograft. While FSGS recurrence has been extensively described…
  • 2022 American Transplant Congress

    Clinical Characteristics Of Serologic Non-responders To Covid-19 Booster Vaccination In A Cohort Of Solid Organ Transplant Recipients.

    F. N. Zervou1, K. Khalil1, T. Lao1, D. Wood2, S. Jonche1, A. Mattoo1

    1Transplant Institute, NYU Langone Health, New York, NY, 2New York University Langone Health, Brooklyn, NY

    *Purpose: The purpose of this study was to assess the clinical characteristics of serologic non-responders to COVID-19 booster vaccination in a cohort of solid organ…
  • 2022 American Transplant Congress

    Role of Vaccination in the COVID-19 Nationwide Cohort (N3C) of Solid Organ Transplant Recipients

    A. J. Vinson1, A. Anzalone2, R. Dai2, E. French3, A. Olex3, J. Sun4, G. Agarwal5, S. Lee6, R. B. Mannon7

    1Nova Scotia Health Authority, Halifax, NS, Canada, 2University of Nebraska Medical Center, Omaha, NE, 3Wright Center for Clinical and Translational Research, Richmond, VA, 4Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, 5University of Alabama at Birmingham, Birmingham, AL, 6University of Saskatchewan, Regina, SK, Canada, 7Medicine, University of Nebraska Medical Center, Omaha, NE

    *Purpose: Immunosuppressed solid organ transplant (SOT) patients have been repeatedly challenged in the COVID-19 pandemic with significant morbidities and mortality following infection and a suppressed…
  • 2022 American Transplant Congress

    Post-Acute Sequelae of Sars-Cov-2 Infection in Solid Organ Transplant Recipients

    S. Alasfar1, T. Chiang1, A. J. Snyder2, M. T. Ou1, B. Boyarsky1, A. T. Abedon1, J. L. Alejo1, W. Cochran1, J. M. Garonzik-Wang3, D. C. Brennan1, T. Vannorsdall1, D. L. Segev1, R. K. Avery1

    1Johns Hopkins University, Baltimore, MD, 2University of Washington, Seattle, WA, 3University of Wisconsin, Madison, WI

    *Purpose: Post-acute sequelae of SARS-CoV-2 infection (PASC) is an increasingly recognized phenomenon manifested by long lasting cognitive, mental, and physical symptoms. We aimed to estimate…
  • 2022 American Transplant Congress

    SARS-CoV-2 Antibody Response by mRNA Vaccine Platform in Incrementally Immunosuppressed Patients

    J. Mitchell1, C. Connolly1, T. Chiang1, J. Alejo1, W. Werbel1, D. Segev1, A. Massie2

    1Johns Hopkins University, Baltimore, MD, 2Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: This study compares SARS-CoV-2 antibody responses between the two-dose mRNA-1273 and BNT162b2 vaccine series across groups of incrementally immunosuppressed patients.*Methods: Semiquantitative testing for antibodies…
  • 2022 American Transplant Congress

    Outcomes of Sensitized Simultaneous Liver-Kidney Transplant

    E. R. Kitchel, T. Tan, A. Wadhwa, D. G. Farmer, S. Bunnapradist

    David Geffen School of Medicine, Los Angeles, CA

    *Purpose: Pre-formed donor-specific HLA antibodies (DSAs) in simultaneous liver-kidney transplants (SLKTs) have been associated with increased risk of antibody mediated rejection (AMR) and negative transplant…
  • 2022 American Transplant Congress

    A Randomised Trial Of Normothermic Machine Perfusion Versus Static Cold Storage In Donation After Circulatory Death Renal Transplantation

    S. Hosgood1, C. Callaghan2, C. Wilson3, G. Oniscu4, B. Phillips5, L. Bates3, L. Smith6, M. L. Nicholson7

    1Surgery, University of Cambridge, Cambridge, United Kingdom, 2Transplant, Guys & St Thomas's, London, United Kingdom, 3Transplant, Freeman Hospital, Newcastle, United Kingdom, 4Edinburgh Royal Infirmary, Edinburgh, United Kingdom, 5Transplant, Guy's & St Thomas's, London, United Kingdom, 6NHSBT, NHSBT, Bristol, United Kingdom, 7University of Cambridge, Cambridge, United Kingdom

    *Purpose: Kidneys from donation after circulatory death (DCD) donors are more susceptible to cold storage injury and have a high risk of delayed graft function…
  • 2022 American Transplant Congress

    Deceased Donor Organ Flush with Similar Volumes of HTK and UW at a Single U.S. Organ Procurement Organization: Adult and Pediatric Data

    A. E. Mangus1, C. Kubal2, B. Ekser3, P. Mihaylov4, A. J. Lutz1, J. Fridell5, R. Mangus6

    1Indiana University Purdue University of Indianapolis, Indianapolis, IN, 2Indiana University Hospital, Indianapolis, IN, 3Surgery, Indiana University - Transplant Surgery, Indianapolis, IN, 4Indiana Univ School of Medicine, Indianapolis, IN, 5Indiana University School of Medicine, Indianapolis, IN, 6Indiana University, Indianapolis, IN

    *Purpose: Histidine-tryptophan-ketoglutarate (HTK) and University of Wisconsin (UW) solutions are the two primary solid-organ preservation solutions used in the United States (>95%), but flush volumes…
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