Abstracts Archive - Page 72 of 1683 - ATC Abstracts

2022 American Transplant Congress
Immune Checkpoints, Immune Cells, and MHC Expression in the Tumor Microenvironment of Resected Hepatocellular Carcinomas
A. Baquerizo¹, V. Vavinskaya², S. Bagsic¹, A. Rojas³, A. Mhoyan⁴, C. Frenette¹, L. Sher⁵, M. Romero³, J. Fisher¹, C. Marsch¹, R. Schaffer¹
¹Scripps, La Jolla, CA, ²UCSD, San Diego, CA, ³University, Seville, Spain, ⁴Kaiser, San Diego, CA, ⁵USC, Los Angeles, CA
*Purpose: Advances in tumor biology has shown the important role of the tumor microenvironment (TME) in tumor growth and metastasis. A better understanding of the…
2022 American Transplant Congress
Organ Transplantation From Donors With Active Sars-cov-2 Infection: The Italian Experience
P. A. Grossi¹, R. Romagnoli², S. Gruttadauria³, M. Colledan⁴, L. De Carlis⁵, S. Martin-Suarez⁶, G. M. Ettorre⁷, F. Parisi⁸, F. Di Benedetto⁹, U. Maggiore¹⁰, G. Tisone¹¹, E. Andorno¹², M. Carmellini¹³, L. G. Lupo¹⁴, U. Livi¹⁵, A. Montemurro¹⁶, L. Lombardini¹⁷, M. Cardillo¹⁸
¹Medicine and Surgery, Univ degli Studi dell'Insubria, 21100 Varese, Italy, ²Liver Transplant Center -General Surgery 2U, University of Turin, Torino, Italy, ³Abdominal Surgery and Organ Transplantation Unit, ISMETT, Palermo, Italy, ⁴Medicine and Surgery, Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy, ⁵CHIRURGIA GENERALE E DEI TRAPIANTI, A.O. Ospedale Niguarda Ca' Granda, 20162 Milano, Italy, ⁶Cardio Thoracic and Vascular Department, University of Bologna S.Orsola - Malpighi, 40138 Bologna, Italy, ⁷Dipartimento Interaziendale Trapianti Silvio Natoli, A.O. San Camillo - Forlanini, 00149 Roma, Italy, ⁸DIPARTIMENTO CARDIOCHIRURGIA CARDIOLOGIA E TRAPIANTO CUORE POLMONE, Ospedale Bambino Gesù, 00165 Roma, Italy, ⁹Medicine and Surgery, AOU Policlinico, 41124 Modena, Italy, ¹⁰Dipartimento di Medicina Generale e Specialistica, Ospedale Maggiore - Parma, 21100 Varese, Italy, ¹¹Chirurgia Generale, A.O.U. Policlinico Tor Vergata, 00133 Roma, Italy, ¹²Dipartimento di Chirurgia, Ospedale Policlinico San Martino, 16132 Genova, Italy, ¹³Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze, A.O.U. Senese - S.M. Alle Scotte, 53100 Siena, Italy, ¹⁴E’mergenza e trapianti di organi, AOU Consorziale Policlinico, 70124 Bari, Italy, ¹⁵Medicine and Surgery, Azienda Sanitaria Universitaria Integrata di Udine, 33100 Udine, Italy, ¹⁶Centro Nazionale Trapianti Operativo, CNT, 00162 Roma, Italy, ¹⁷Medical DirectOR, CNT, 00162 Roma, Italy, ¹⁸General Director, CNT, 00162 Roma, Italy
*Purpose: In the present study we want to report safety and outcome of organ transplantation from donors with active SARS-CoV-2 infection in Italy.*Methods: In November…
2022 American Transplant Congress
Ventricular Modeling Following Bariatric Surgery Decreases Need for Heart Transplantation
R. Choudhury¹, A. Rouhi², G. Hoeltzel³, Y. Bababekov¹, A. Suarez-Pierre⁴, A. Yule¹, N. Vigneshwar⁴, N. Williams⁵, K. Dumon², T. Nydam¹
¹Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, ³General Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, ⁴Cardiothoracic Surgery, University of Colorado Hospital, Aurora, CO, ⁵General Surgery, Hospital of the University of Pennsylvania, Aurora, CO
*Purpose: For obese patients with congestive heart failure (CHF), aggressive weight loss has been associated with ventricular remodeling. Many have suggested offering bariatric surgery for…
2022 American Transplant Congress
Evaluation of Prophylactic Valganciclovir Dosing in Kidney Transplant Recipients at an Urban Transplant Institution
E. Foster¹, D. Pierce¹, T. Cairns¹, S. Borgetti², I. Tzvetanov³, E. Benedetti³, C. Muran¹
¹Pharmacy, University of Illinois at Chicago, Chicago, IL, ²Medicine, University of Illinois at Chicago, Chicago, IL, ³Surgery, University of Illinois at Chicago, Chicago, IL
*Purpose: Dosing and duration of cytomegalovirus (CMV) prophylaxis with valganciclovir (VGC) in kidney transplant (KT) recipients is variable by transplant center. Prior studies have shown…
2022 American Transplant Congress
Disparities in Low Respiratory Vaccination Among Solid Organ Transplant Recipients
J. R. Felzer¹, A. M. LeMahieu², L. J. Finney Rutten², Y. Juhn³, C. Wi³, R. M. Jacobson³, C. C. Kennedy¹
¹Medicine, Mayo Clinic, Rochester, MN, ²Quantitative Health Sciences, Mayo Clinic, Rochester, MN, ³Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN
*Purpose: There are many potential infections post-transplant, with influenza as the most common vaccine-preventable infection the first 5 years post-transplant. Despite effective vaccines, uptake is…
2022 American Transplant Congress
PSGL-1-mTOR-TIM3 Signaling in a Murine Model of Hindlimb Transplantation
K. Kadono¹, F. Messner², J. He², Y. Guo², B. Oh², G. Brandacher², J. Kupiec-Weglinski¹
¹UCLA Medical Center, Los Angeles, CA, ²Johns Hopkins UJohns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Peri-transplant tissue damage driven by innate-adaptive immune cascades resulting from ischemia-reperfusion injury (IRI) is a major concern in vascularized composite allotransplantation (VCA). Here, we…
2022 American Transplant Congress
Incidence of Urinary Tract Infection or Asymptomatic Bacteriuria in Kidney Transplant Recipients with Sulfamethoxazole-Trimethoprim vs. Pentamidine for Pneumocystis Jiroveci Pneumonia Prophylaxis
L. Selznick, H. Sweiss, C. Long, S. Bhayana, R. Hall
University Health, San Antonio, TX
*Purpose: To compare the incidence of urinary tract infection (UTI) or asymptomatic bacteriuria (ASB) post-kidney transplant (KT) with multiple Pneumocystis jiroveci pneumonia (PJP) prophylaxis regimens*Methods:…
2022 American Transplant Congress
Defatting of Steatotic Liver Grafts by Normothermic Ex Vivo Liver Machine Perfusion with 2,4 Dinitrophenol
J. M. Gassner¹, J. Michelotto¹, S. Moosburner¹, F. Strobl¹, A. L. Birkenfeld², A. Kurzbach², G. Shulman³, X. Zhang³, M. Selzner⁴, Y. Noguchi⁴, J. Pratschke¹, I. M. Sauer¹, N. Raschzok¹
¹Department of Surgery, Experimental Surgery, Charité – Universitätsmedizin Berlin, Berlin, Germany, ²Division of Endocrinology, Diabetology and Nephrology, Department of Internal Medicine, Internal, University Hospital Tübingen, Tübingen, Germany, ³Departments of Internal Medicine and Cellular & Molecular Physiology, Yale Diabetes Research Center, Yale School of Medicine, New Haven, CT, ⁴Multi Organ Transplant Program, Ajmera Family Transplant Center, Toronto General Hospital, University of Toronto, Toronto, ON, Canada
*Purpose: The purpose of the study is to demonstrate that steatotic liver grafts can be defatted by normothermic ex vivo liver machine perfusion (NEVLP) with…
2022 American Transplant Congress
Mass Cytometry Reveals Single-cell Kinetics Of Cytotoxic Lymphocyte Evolution In Cmv-infected Renal Transplant Patients
K. Ishiyama¹, J. Arakawa-Hoyt¹, O. Aguilar¹, T. Sigdel¹, S. Tamaki¹, J. Babdor¹, M. Spitzer¹, E. Reed², M. Sarwal³, L. Lanier¹
¹UCSF, San Francisco, CA, ²Univ of California LA, Los Angeles, CA, ³University of California San Francisco, San Francisco, CA
*Purpose: Cytomegalovirus (CMV) infection is associated with graft rejection in renal transplantation. Memory-like NK cells expressing NKG2C and lacking FcεRIγ are established during CMV infection.*Methods:…
2022 American Transplant Congress
Outcomes in Kidney Transplant Recipients 70 Years and Older
J. Mehta, N. F. Okonkwo, A. Paramesh, K. Atiemo, M. Killackey, H. Jeon, A. Vijay
Tulane University School of Medicine, New Orleans, LA
*Purpose: Patients older than 70 years are the fastest-growing age group of patients requiring renal replacement therapy. This has resulted in a corresponding increase in…