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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Rates Of Dermatology Follow-up And New Skin Cancer Diagnosis Among Solid Organ Transplant Recipients During The Covid-19 Pandemic

    R. Saranath, J. Gomez, B. Fernandez, E. Shah, S. Michalak, I. Ahronowitz

    USC Keck School of Medicine, Los Angeles, CA

    *Purpose: Solid organ transplant recipients (SOTRs) are at an elevated risk of developing non-melanoma skin cancers. Routine dermatologic surveillance has been shown to improve skin…
  • 2022 American Transplant Congress

    Trends in Prescribing Gabapentinoids, Co-Prescribed with Opioids or Benzodiazepines Among Kidney Transplant Recipients

    J. Ahn1, S. Bae1, J. Kim1, M. Schnitzler2, G. Hess3, K. Lentine2, D. Segev1, M. McAdams-DeMarco1

    1Johns Hopkins University, Baltimore, MD, 2Saint Louis University, St. Louis, MO, 3Drexel University, Philadelphia, PA

    *Purpose: Gabapentinoid are commonly used to manage neuropathic pain in recipients with kidney transplantation (KT), with increasing concerns of co-prescribing with opioids and benzodiazepines leading…
  • 2022 American Transplant Congress

    Evaluation of Compliance and Efficacy with Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Tacrolimus in Kidney Transplant Recipients

    M. Nikirk1, J. Chen1, E. Tillman2

    1Indiana University Health, Indianapolis, IN, 2Indiana University School of Medicine, Indianapolis, IN

    *Purpose: The purpose of this study is to evaluate compliance and efficacy of The Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 genotype guided tacrolimus…
  • 2022 American Transplant Congress

    In Vitro Fertilization Use Among Female Kidney Transplant Recipients

    L. A. Coscia1, J. M. Konel2, M. Bowring3, S. Constantinescu4, M. J. Moritz5

    1Transplant Pregnancy Registry International, Philadelphia, PA, 2Wayne State University School of Medicine, Detroit, MI, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 5Surgery, Lehigh Valley Health Network, Allentown, PA

    *Purpose: Infertility is common among female kidney transplant recipients (KTRs). In vitro fertilization (IVF) is a potential option. The purpose of this study was to…
  • 2022 American Transplant Congress

    p40 Homodimers Stimulate Graft Dendritic Cells to Produce IL-15 Driving Endogenous Donor-Reactive Memory CD8 T Cell Activation within High-Risk Cardiac Allografts

    H. Tsuda1, A. Valujskikh2, R. Fairchild3

    1Inflammation and Immunity, Cleveland Clinic, Cleveland, OH, 2The Cleveland Clinic Fdn, Cleveland, OH, 3Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: Acute allograft injury occurring during the first 1-2 days post-transplant is mediated by graft infiltrating endogenous donor-reactive memory CD8 T cells and requires their…
  • 2022 American Transplant Congress

    Baseline Trends in Tacrolimus Intrapatient Variability in Pediatric and Young Adult Kidney Transplant Recipients

    K. Piburn1, L. Maestretti2, M. V. Patton2, A. M. McGrath2, O. S. Indridason3, A. Chaudhuri1, P. Grimm1, V. Sigurjonsdottir1

    1Pediatric Nephrology, Stanford University, Palo Alto, CA, 2Pediatric Kidney Transplant, Lucile Packard Children's Hospital, Palo Alto, CA, 3Division of Nephrology, Landspitali – the National University Hospital of Iceland, Reykjavik, Iceland

    *Purpose: High tacrolimus intrapatient variability (IPV) is a known risk factor for poor graft outcomes in kidney transplantation. Baseline trends in tacrolimus IPV have not…
  • 2022 American Transplant Congress

    Impact of Maintaining Blood Pressure Goals on Graft Function After Kidney Transplant

    D. Majmundar, A. DiCarlo, S. Karhadkar, A. Diamond, K. Mohrien, P. Szczesniak

    Temple University Hospital, Philadelphia, PA

    *Purpose: Impaired graft function following kidney transplant impacts short- and long-term patient outcomes. Proper management of systolic blood pressure (SBP) in the immediate post-operative period…
  • 2022 American Transplant Congress

    Deceased Donor Organ Flush with Similar Volumes of HTK and UW at a Single U.S. Organ Procurement Organization: Adult and Pediatric Data

    A. E. Mangus1, C. Kubal2, B. Ekser3, P. Mihaylov4, A. J. Lutz1, J. Fridell5, R. Mangus6

    1Indiana University Purdue University of Indianapolis, Indianapolis, IN, 2Indiana University Hospital, Indianapolis, IN, 3Surgery, Indiana University - Transplant Surgery, Indianapolis, IN, 4Indiana Univ School of Medicine, Indianapolis, IN, 5Indiana University School of Medicine, Indianapolis, IN, 6Indiana University, Indianapolis, IN

    *Purpose: Histidine-tryptophan-ketoglutarate (HTK) and University of Wisconsin (UW) solutions are the two primary solid-organ preservation solutions used in the United States (>95%), but flush volumes…
  • 2022 American Transplant Congress

    Covid19 in Pediatric Kidney Transplant Recipients: Incidence, Outcomes, and Response to Vaccine

    A. Moudgil, K. Sgambat, Y. Shi, M. Meyers, C. Petyak, L. Midgley

    Nephrology, Children's National Med. Ctr., Washington, DC

    *Purpose: At the onset of pandemic, no information was available on response of pediatric kidney transplant (PKTX) recipients to COVID19. When COVID19 vaccines became available,…
  • 2022 American Transplant Congress

    Obinutuzumab in Kidney Transplantation: Effect on B-cell Counts and Crossmatch Tests

    M. M. Nasrallah1, M. Elalfy1, Y. Elmesseery2, I. Amer1, P. Malvezzi3, L. Rostaing4

    1Misr International Hospital, Cairo, Egypt, 2Misr International Hospital, Caire, Egypt, 3CHU Grenoble-Alpes, Grenoble, France, 4Service de Néphrologie, CHU Grenoble-Alpes, Grenoble, France

    *Purpose: Resistance to the action of rituximab (RTX), has been documented in several diseases. More recently, obinutuzumab (OBZ) has shown promise where RTX has failed…
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