ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Dendritic Cell Senescence as a Key Contributor to Transplant Rejection

    J. Zhao1, X. Li1, S. Jung1, H. Zhang1, V. Kasinath1, J. Azzi1, P. Sage1, J. Bromberg2, R. Abdi1

    1Brigham and Women’s Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD

    *Purpose: Intra-graft inflammation initiated by ischemia-reperfusion injury (IRI) is an unavoidable consequence of transplantation surgery and constitutes a key source of alloimmune responses. IRI leads…
  • 2022 American Transplant Congress

    Exploration of the Optimal pH in Hypothermic Machine Perfusion for Rat Liver Grafts Retrieved from Circulatory Death

    S. Sakamoto1, M. Fukai1, K. Shibata1, H. Bochimoto2, N. Mohd Zin2, N. Kawamura1, T. Ishikawa1, M. Fujiyoshi1, T. Shimamura3, A. Taketomi1

    1Department of Gastroenterological Surgery 1, Hokkaido University Graduate School, Sapporo, Japan, 2Department of Cell Physiology, The Jikei University School of Medicine, Tokyo, Japan, 3Division of Organ Transplantation, Hokkaido University Hospital, Sapporo, Japan

    *Purpose: Although some investigators have reported favorable results of hypothermic machine perfusion (HMP) in liver transplantation, the efficacy to the hepatic graft retrieved from circulatory…
  • 2022 American Transplant Congress

    Outcomes in Kidney Transplant Recipients 70 Years and Older

    J. Mehta, N. F. Okonkwo, A. Paramesh, K. Atiemo, M. Killackey, H. Jeon, A. Vijay

    Tulane University School of Medicine, New Orleans, LA

    *Purpose: Patients older than 70 years are the fastest-growing age group of patients requiring renal replacement therapy. This has resulted in a corresponding increase in…
  • 2022 American Transplant Congress

    An Updated Estimate of Post-Transplant Survival After Implementation of the New Donor Heart Allocation Policy

    K. A. Lazenby1, N. Narang2, K. M. Pelzer3, G. Ran1, W. F. Parker3

    1Pritzker School of Medicine, University of Chicago, Chicago, IL, 2Advocate Heart Institute, Advocate Christ Medical Center, Chicago, IL, 3Department of Medicine, University of Chicago, Chicago, IL

    *Purpose: Published estimates showing lower post-transplant survival after implementation of the new heart allocation policy may be biased downward due to incomplete follow-up on surviving…
  • 2022 American Transplant Congress

    Clinical Relevance of Class II HLA Mismatches in Living Donor Kidney Transplantation

    J. Lan1, M. Kadatz1, D. Chang1, R. Liwski2, E. Wagner2, P. Campbell2, J. Gill1, J. Gill1

    1University of British Columbia, Vancouver, BC, Canada, 2On behalf of Canadian HLA Advisory Committee, Ottawa, ON, Canada

    *Purpose: The benefit of class II HLA matching is primarily shown in deceased donor kidney transplantation. The objective of this study was to determine the…
  • 2022 American Transplant Congress

    Pharmacogenomic Dosing in Kidney Transplant Patients Converted from Tacrolimus Immediate Release to Tacrolimus Extended Release (Envarsus XR®)

    K. D. Belfield1, K. J. Armstrong2, D. Malhotra3, G. F. Girone1

    1Department of Pharmacy, Yale New Haven Hospital, New Haven, CT, 2Department of Pharmacy, Hospital of Central Connecticut, New Britain, CT, 3Section of Nephrology, Yale School of Medicine, New Haven, CT

    *Purpose: When converting from tacrolimus (tac) immediate release (tacIR) to tac extended release (Envarsus XR; tacXR), the package insert (PI) recommends 80% of the tacIR…
  • 2022 American Transplant Congress

    Clinical Outcomes In A Large Transplant Cohort Hospitalized With COVID-19: Mycophenolate Mofetil (MMF) Utilization And Mortality Trends

    R. L. Gottlieb1, M. Askar2, L. Chen3, A. Chandak4, E. Mozaffari3, M. Thrun3, R. Haubrich3

    1Baylor Scott & White Research Institute, Dallas, TX, 2Baylor University Medical Center, Dallas, TX, 3Gilead Sciences, Foster City, CA, 4Certara, New York, NY

    *Purpose: To characterize demographics, treatment patterns, and outcomes among 3,998 transplant patients hospitalized for COVID-19 over 16 months of the pandemic (May ’20-Aug ’21).*Methods: Adult…
  • 2022 American Transplant Congress

    Improving Access and Equity for Transplant: A Single-Center Experience

    S. Kodali1, A. Lopez2, C. Egwim2, J. Alegria2, S. Yi2, H. Adrogue2, M. Moaddab2, H. Huang2, I. Hussain2, M. Kassi2, J. Ontiveros2, R. Guardiola2, J. Alexander2, D. Harvey2, K. Maresh2, S. Zylicz2, L. Loza2, J. Corkrean2, A. O. Gaber2, R. M. Ghobrial1

    1Sherrie and Alan Conover Center for Liver Disease & Transplantation, Houston Methodist Hospital, Houston, TX, 2Houston Methodist Hospital, Houston, TX

    *Purpose: Many Hispanic Americans have misconceptions about transplantation due to language and cultural differences, which can make them less likely to undergo liver transplant (LT)…
  • 2022 American Transplant Congress

    Ventricular Modeling Following Bariatric Surgery Decreases Need for Heart Transplantation

    R. Choudhury1, A. Rouhi2, G. Hoeltzel3, Y. Bababekov1, A. Suarez-Pierre4, A. Yule1, N. Vigneshwar4, N. Williams5, K. Dumon2, T. Nydam1

    1Transplantation Surgery, University of Colorado Hospital, Aurora, CO, 2General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 3General Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, 4Cardiothoracic Surgery, University of Colorado Hospital, Aurora, CO, 5General Surgery, Hospital of the University of Pennsylvania, Aurora, CO

    *Purpose: For obese patients with congestive heart failure (CHF), aggressive weight loss has been associated with ventricular remodeling. Many have suggested offering bariatric surgery for…
  • 2022 American Transplant Congress

    Comparison of Outcomes of Covid-19 Between Fully Vaccinated and Unvaccinated Kidney Transplant Recipients and According to the Type of M-RNA Vaccine

    F. Villanego1, M. Crespo2, V. Lopez3, S. Zarraga4, F. Oppenheimer5, L. Llinas2, A. Andres6, C. Diaz7, M. Ruiz8, F. Moreso9, A. Rodriguez-Benot10, I. Beneyto11, S. Cabello12, C. Jimenez13, C. Canal14, M. Molina15, J. Pascual6, A. Mazuecos1

    1Department of Nephrology, Hospital Puerta del Mar, Cadiz, Spain, 2Department of Nephrology, Hospital del Mar, Barcelona, Spain, 3Department of Nephrology, Hospital Regional de Malaga, Malaga, Spain, 4Department of Nephrology, Hospital de Cruces, Baracaldo, Spain, 5Department of Nephrology, Hospital Clinic, Barcelona, Spain, 6Department of Nephrology, Hospital 12 de Octubre, Madrid, Spain, 7Department of Nephrology, Hospital Central de Asturias, Oviedo, Spain, 8Department of Nephrology, Hospital Virgen de las Nieves, Granada, Spain, 9Department of Nephrology, Hospital Vall d'Hebron, Barcelona, Spain, 10Department of Nephrology, Hospital Reina Sofia, Cordoba, Spain, 11Department of Nephrology, Hospital La Fe, Valencia, Spain, 12Department of Nephrology, Hospital Son Espases, Palma de Mallorca, Spain, 13Department of Nephrology, Hospital La Paz, Madrid, Spain, 14Department of Nephrology, Fundacion Puigvert, Barcelona, Spain, 15Department of Nephrology, Hospital Germans Trias i Pujol, Badalona, Spain

    *Purpose: The evidence regarding the clinical effectiveness of COVID-19 vaccination in kidney transplant (KT) recipients is limited so far. Our purpose is to analyze the…
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