ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Association Between Allograft Gene Expression and Acute Cellular Rejection Grade in Heart Transplant Recipients

    A. Kao1, K. Haffey2, K. T. Gondi3, J. Linard2, C. Knutson2, K. Morgan2, L. Teterina2, S. Williams2, K. Oreschak4, H. Zhang4

    1St. Luke's Health System Kansas City Mid America Heart Institute, Kansas City, MO, 2St. Luke's, Kansas City, MO, 3University of Michigan, Ann Arbor, MI, 4CareDx, South San Francisco, CA

    *Purpose: Endomyocardial biopsy (EMB) remains the gold standard in acute rejection (AR) surveillance in heart transplantation (HT) despite interpretation subjectivity and low concordance rates between…
  • 2022 American Transplant Congress

    Steatosis Following Liver Transplantation for Nonalcoholic Steatohepatitis is Associated with a Higher Rate of Cardiovascular Complications

    W. Alhamoudi1, S. Alqahtani2, K. Bzeizi2, A. Albenmousa2, Y. Saleh2, D. Broering2, S. Alghamdi2

    1Medicine, King Saud University, Riyadh, Saudi Arabia, 2Liver Transplantation, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

    *Purpose: Cirrhosis secondary to Nonalcoholic Steatohepatitis (NASH) is projected to become the leading indication for liver transplantation (LT) worldwide. Objectives: to evaluate the prevalence of…
  • 2022 American Transplant Congress

    Tacrolimus After Rabbit Antithymocyte Globulin And Infliximab Induction Immunosuppression In Kidney Transplantation

    O. Viklicky1, G. Bold2, O. Bestard3, P. Hruba1, I. Zahradka1, N. M. Otto2, M. Stein2, A. Sefrin2, S. Christakoudi4, P. M. Reinke2

    1Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 2Charité, Berlin, Germany, 3Vall d'Hebron, Barcelona, Spain, 4King's College, London, United Kingdom

    *Purpose: Selective targeting of effector/memory T cells as induction immunosuppression has been discussed in kidney transplantation. Confidence-interval-estimation study may help to estimate range of the…
  • 2022 American Transplant Congress

    Technology Enabled And Molecular Monitoring Of The Allograft And Transplant Recipient Study

    N. Sulejmani1, D. Axelrod2, S. Dholakia1, S. Shah3

    1CareDx, South San Francisco, CA, 2University of Iowa, Iowa City, IA, 3University of Cincinnati, Cincinnati, OH

    *Purpose: With the widespread availability of smart mobile devices, mobile health (mHealth) provides the opportunity to reach wide array of patients. Readmission rates as high…
  • 2022 American Transplant Congress

    Single Kidney Transplantation from Small Pediatric Donors Aged < 2 Years Into Pediatric Recipients: A Retrospective Single-Center Cohort Study

    Q. Zhang, M. Huang, J. Li, W. Wu, H. Zhang, C. Wu, Q. Fu, P. Gao, L. Ling, W. Chen, B. Xu, X. Su, L. Liu, C. Wang

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China

    *Purpose: Kidneys from small pediatric donors (aged < 2 years, SPD) are underutilized. Concerns regarding potentially inferior outcomes hinder the use in pediatric recipients, especially…
  • 2022 American Transplant Congress

    Retransplantation in a High-Volume Institution: Historical, Socioeconomic and Survival Trends

    D. von Ahrens, O. Sulimani, M. Holzner, M. Akhtar, S. Florman, A. Arvelakis

    The Mount Sinai Hospital, New York, NY

    *Purpose: Retransplantation for liver allograft failure is a challenge within the field. The evolution of organ allocation policy from Child to MELD in 2002 and…
  • 2022 American Transplant Congress

    Functional Recellularized Patient Derived Endothelium; A Human Vascular Graft Approach

    H. Tejeda Mora1, J. Willemse2, Y. den Hartog1, I. Schurink2, M. M. Verstegen2, J. de Jonge2, R. C. Minnee2, M. W. van den Hoogen2, C. C. Baan1, L. J. van der Laan2, M. J. Hoogduijn1

    1Transplant Institute - Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands, 2Transplant Institute - Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands

    *Purpose: In transplantation, the endothelial lining is the first barrier between the donor organ and recipient immune system. Damaged endothelium exposes extracellular matrix (ECM) molecules…
  • 2022 American Transplant Congress

    Decellularized Human Pancreatic Extracellular Matrix-Based Physiomimetic Microenvironment for Human Islet Culture

    A. Asthana1, D. Chaimov1, R. Tamburrini2, S. J. Walker3, G. Orlando1

    1Wake Forest Baptist Medical Center, Winston-Salem, NC, 2University of Wisconsin Hospital and Clinics, Madison, WI, 3Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC

    *Purpose: Maintenance of human islet viability and function ex vivo can be a significant bottleneck for both regenerative medicine as well as tissue engineering applications.…
  • 2022 American Transplant Congress

    Superoxide in Cardiac Allografts from Donors After Circulatory Death

    M. Urban1, T. Bruett2, K. F. Duncan1, N. W. Markin3, M. M. Chacon3, M. C. Zimmerman4

    1Department of Surgery. Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE, 2College of Medicine. Department of Cellular and Integtrative Physiology., University of Nebraska Medical Center, Omaha, NE, 3Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, 4Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE

    *Purpose: Quality of cardiac allografts from donors after circulatory death (DCD) is adversely impacted by warm ischemia and subsequent reperfusion during organ resuscitation. Post-transplant myocardial…
  • 2022 American Transplant Congress

    CD8+ T Cells Differentiate into a CD43-expressing Effector Population After Transplantation

    G. Cohen, M. A. Kallarakal, S. M. Krummey

    Department of Pathology, Johns Hopkins University, Baltimore, MD

    *Purpose: Despite a significantly reduced toxicity profile and improved long-term graft function versus calcineurin inhibitors, widespread adaptation of belatacept (CTLA-4 Ig) has been limited due…
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