Abstracts Archive - Page 69 of 1683 - ATC Abstracts

2022 American Transplant Congress
Sirolimus Use Is Associated With An Improved Immune Response To Covid-19 Vaccination In Kidney Transplant Recipients
G. B. Perkins¹, M. Tunbridge², T. Salehi², C. Chai¹, C. M. Hope¹, P. Garcia-Valtanen¹, J. J. Singer³, P. R. Hurtado², S. C. Barry¹, B. Grubor-Bauk¹, P. Hissaria², S. J. Chadban³, P. Coates¹
¹University of Adelaide, Adelaide, Australia, ²Royal Adelaide Hospital, Adelaide, Australia, ³Royal Prince Alfred Hospital, Sydney, Australia
*Purpose: Kidney transplant recipients (KTRs) are highly vulnerable to severe COVID-19, however are poorly protected by vaccination. Additional vaccine doses have achieved limited improvements in…
2022 American Transplant Congress
Impaired Humoral Response to Second Dose of BNT162b2 Messenger RNA COVID-19 Vaccine in Kidney Transplant Recipients in Japan: Prospective Observational Study
H. Sasaki¹, K. Hasegawa¹, M. Miura², H. Harada¹, D. Takamoto¹, Y. Takada¹, S. Harada¹, H. Tanaka¹
¹Sapporo City General Hospital, Sapporo, Japan, ²Sapporo Hokuyu Hospital, Sapporo, Japan
*Purpose: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has a major impact on solid organ transplant (SOT) recipients, with mortality rate up to 22%. The…
2022 American Transplant Congress
Long-Term Insulin Independence Achieved by a Multimodal Approach to Beta-Cell Replacement in Patients with Type I Diabetes
M. Nunez¹, S. Wisel², J. Gardner³, G. Worner⁴, G. Roll⁵, S. Syed³, G. Szot¹, M. Tavakol¹, K. Johnson¹, A. Posselt⁴, P. Stock⁶
¹Surgery, University of California, San Francisco, San Francisco, CA, ²Cedars-Sinai Medical Center, Los Angeles, CA, ³University of California, San Francisco, San Francisco, CA, ⁴University of California San Francisco, San Francisco, CA, ⁵UCSF Medical Center, San Francisco, CA, ⁶Univ of California-San Francisco, San Francisco, CA
*Purpose: Long-term insulin independence in beta-cell replacement, via islet or pancreas transplant, remains limited by the toxic effects of calcineurin inhibitors (CNI) on beta cells…
2022 American Transplant Congress
Impact of Glecaprevir/Pibrentasvir on Tacrolimus Concentration in Solid Organ Transplant Recipients with or without Triazole Antifungal Therapy
D. Abraham¹, A. Feist², N. Law¹, S. Aslam¹, V. Nguyen¹
¹University of California San Diego Health, San Diego, CA, ²University of California San Diego, San Diego, CA
*Purpose: Provide guidance on tacrolimus (TAC) dose adjustments during glecaprevir/pibrentasvir (GLE/PIB) initiation and discontinuation in patients on triazole antifungals by comparing changes in TAC concentration-dose…
2022 American Transplant Congress
Case-Control Study of Belatacept as Maintenance Immunosuppression in Kidney Transplant Recipients Living with HIV
M. Tucker, C. Foppiano Palacios, E. Cohen, S. Virmani, P. Trubin, L. A-Barakat, M. M. Azar, M. Malinis
Yale School of Medicine, New Haven, CT
*Purpose: Belatacept has been increasingly used in kidney transplant recipients (KTR) as a calcineurin-inhibitor (CNI) sparing agent. There are little data on belatacept use in…
2022 American Transplant Congress
Demographic Characteristics of VCA Candidates and Recipients in the U.S.
J. Wainright¹, L. Cartwright¹, A. Henderson¹, W. Cherikh¹, S. Booker¹, D. Klassen²
¹Research, UNOS, Richmond, VA, ²Office of the Chief Medical Officer, UNOS, Richmond, VA
*Purpose: As with other fields of transplantation, it is important to understand the populations VCA transplantation is serving.*Methods: This study used OPTN VCA waiting list…
2022 American Transplant Congress
The New Heart Allocation Policy Has Increased Listing by Exception
J. R. Golbus¹, Y. Ahn², B. K. Nallamothu¹, M. N. Walsh³, D. Zaun², A. Israni², M. Colvin¹
¹University of Michigan, Ann Arbor, MI, ²Hennepin Healthcare Research Institute, Minneapolis, MN, ³Ascension St. Vincent Heart Center, Carmel, IN
*Purpose: The new heart allocation policy (October 2018) expanded the number of listing statuses and established a national review board for exception requests in an…
2022 American Transplant Congress
Basiliximab Provides Similar Efficacy and Renal Recovery in Steroid-Minimal Liver Transplantation
L. Bowman¹, A. Webb¹, Y. Alsalihi², F. Fakhre³, R. Baliga⁴, V. Subramanian⁵, K. Robichaux³, S. Mohammed³, M. Gosselin⁶, J. Buggs⁵, A. Kumar⁷
¹Transplant Pharmacy, Tampa General Hospital, Tampa, FL, ²California Health Sciences University, Clovis, CA, ³University of South Florida, Tampa, FL, ⁴Florida Kidney Physicians, Tampa, FL, ⁵Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁶University of Tampa, Tampa, FL, ⁷Morsani College of Medicine, University of South Florida, Tampa, FL
*Purpose: Due to nephrotoxic effects of tacrolimus, previous studies have evaluated the utility of basiliximab to delay or reduce tacrolimus for renal preservation in orthotopic…
2022 American Transplant Congress
A2/A2B to B Kidney Transplantation Outcomes: A Single-Center 5 Year Experience
A. El Chediak, S. Shawar, M. Fallahzadeh, I. Feurer, S. Rega, J. L. Triozzi, D. Shaffer
Vanderbilt University Medical Center, Nashville, TN
*Purpose: The new kidney allocation system (KAS) instituted in 2014 allowed organ procurement organizations to allocate A2/A2B to B candidates preferentially was meant to improve…
2022 American Transplant Congress
Zfyve21 Activates T Cell Intrinsic, Nlrp3 Inflammasomes to Promote Allograft Vasculopathy
D. Antoine¹, B. Jiang¹, Q. Jiang¹, X. Li¹, S. Guiyu¹, M. Fan¹, G. Tellides², A. Geirsson³, D. Jane-wit³
¹Dept of Cardiovascular Medicine, Yale University, New Haven, CT, ²Dept of Cardiothoracic Surgery, Yale University, New Haven, CT, ³Yale University, New Haven, CT
*Purpose: Allograft vasculopathy (AV) is a complication of chronic allograft rejection whose underlying mechanism(s) of etiopathogenesis are poorly defined. We examined the role of ZFYVE21,…