2022 American Transplant Congress
Identification of a Human B Cell State with Allogeneic Antigen Cross-Presenting Potential
Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA
*Purpose: B cells are known to play a significant role in allograft tolerance or rejection, largely determined by production of cytokines and antibodies that suppress…2022 American Transplant Congress
Simultaneous Liver/ Kidney Transplant Reduces Both Donor Specific and Non-Donor Specific HLA Antibodies
Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: Kidney allografts can be transplanted across strong donor specific antibody (DSA) barriers in simultaneous liver/kidney transplant (SLK) recipients. It is suggested that preformed DSAs…2022 American Transplant Congress
The Impact of Yttium-90 Radioembolization on T Cell Phenotypes in Bridged to Transplant Hepatocellular Carcinoma Patients
Ochsner Health System, New Orleans, LA
*Purpose: Response to locoregional therapy (LRT) in hepatocellular carcinoma (HCC) impacts both progression-free survival (PFS) and bridge to transplant success. Yttrium-90 (Y90) is an effective…2022 American Transplant Congress
Experience with Covid-19 Infection and Vaccination in Combined Kidney/HSCT Recipients
1Northwestern University, Chicago, IL, 2University of Louisville, Louisville, KY
*Purpose: Kidney transplant(KTx) recipients are at increased risk of COVID-19 related complications. KTx pts who have undergone therapy to induce tolerance are a unique cohort…2022 American Transplant Congress
Validation of Shared T Cell Epitope Analysis as a Tool to Detect Preformed Donor-Reactive CD4+ Memory T-helper Cells
*Purpose: Adaptive immunity creates immunological memory after the first response to a specific foreign antigen including HLA. During this response, adaptive immunity memorizes the molecular…2022 American Transplant Congress
The Impact Of Covid-19 On Pediatric Organ Donation And Transplantation
*Purpose: The global COVID-19 pandemic has significantly altered delivery of healthcare. Hospital resource utilization has been impacted on multiple levels including solid organ transplantation and…2022 American Transplant Congress
A New Algorithm Combining Donor Derived Cell-Free DNA Fraction and Quantity to Detect Kidney Transplant Rejection Using Molecular Diagnoses and Histology
1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2Natera, Inc., Austin, TX
*Purpose: Donor derived cell-free DNA (dd-cfDNA) has been shown to be associated with allograft rejection, both histological and molecular (JASN, in press). Clinically available dd-cfDNA…2022 American Transplant Congress
Survival Comparison of Simultaneous Pancreas-Kidney Transplant with Pancreas After Living-Donor Kidney Transplant by Wait Time and Organ Quality
*Purpose: The survival benefit of simultaneous pancreas-kidney (SPK) compared to pancreas after living-donor kidney (PALK) transplant is controversial. Wait times for SPK and donor risk…2022 American Transplant Congress
Two Times or More Double-Filtration Plasmapheresis Increases the Risk of Bleeding During Kidney Transplantation
Urology, Tokyo Women's Medical University, Tokyo, Japan
*Purpose: Double-filtration plasmapheresis (DFPP) is effective for desensitization in ABO incompatible and highly sensitized transplantation. In such cases, bleeding is difficult to stop due to…2022 American Transplant Congress
Evaluation of Compliance and Efficacy with Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Tacrolimus in Kidney Transplant Recipients
*Purpose: The purpose of this study is to evaluate compliance and efficacy of The Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 genotype guided tacrolimus…
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