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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Status Exception Use in the New Seven-Tiered Heart Allocation System

    A. Plana1, A. Kanelidis1, W. F. Parker2, V. Jeevanandam3, C. Salerno3, B. Smith1, S. Kalantari1, S. Pinney1, J. Grinstein1

    1Cardiology, University of Chicago, Chicago, IL, 2Pulmonary/Critical Care, University of Chicago, Chicago, IL, 3Cardiac Surgery, University of Chicago, Chicago, IL

    *Purpose: The revised seven-tiered US heart allocation policy aimed to improve risk stratification to lower exception status use. However, recent literature has demonstrated that exceptions…
  • 2022 American Transplant Congress

    Xenogeneic Cross-Circulation Supports Ex Vivo Human Livers for 24 Hours

    W. K. Wu1, R. Ukita2, Y. J. Patel2, I. A. Ziogas3, M. Cortelli2, M. Mentz2, J. R. Talackine2, S. A. Francois2, N. L. Cardwell2, J. W. Stokes2, S. P. Alexopoulos3, M. Bacchetta2

    1Hepatobiliary Surgery and Liver Transplantation; Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, 2Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, 3Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Despite increasing use of machine perfusion as an organ preservation and rescue technique in liver transplantation, significant organ shortages and waitlist mortality highlight a…
  • 2022 American Transplant Congress

    Sars-cov-2 Antibodies Transitions After Vaccination In Solid Organ Transplant Recipients: Multicenter Study In Japan

    K. Unagami1, M. Yoshikawa2, Y. Natori3, K. Omoto1, H. Ishida1, H. Date4, R. Imamura5, T. Ito4, K. Miyaji6, S. Takahara7, K. Yuzawa8, O. Satoko9, Y. Hirota10, H. Egawa1

    1Tokyo Women's Medical University, Tokyo, Japan, 2Kyoto Prefectural University of Medicine, Kyoto, Japan, 3University of Miami, Pinecrest, FL, 4Kyoto University, Kyoto, Japan, 5Dept. of Urology, Osaka Univ. Graduate School of Medicine, Suita, Japan, 6Renal Transplantation, Takatsuki General Hospital, Takatsuki, Japan, 7Kansai Medical Hospital, Toyonaka, Japan, 8Tranplantation Surgery, National Hospital Organization Mito Medical Center, Mito, Japan, 9Public Health, Osaka City University Graduate School of Medicine and Research Center for Infectious, Osaka City University Graduate School of Medicine, Osaka, Japan, 10Clinical Epidemiology Research Center, Miyama, Japan

    *Purpose: For purpose of SARS-CoV-2 infection control, vaccination was started in worldwide, however, low reactivity of antibody production after vaccination is a concern for solid…
  • 2022 American Transplant Congress

    Disparities in Low Respiratory Vaccination Among Solid Organ Transplant Recipients

    J. R. Felzer1, A. M. LeMahieu2, L. J. Finney Rutten2, Y. Juhn3, C. Wi3, R. M. Jacobson3, C. C. Kennedy1

    1Medicine, Mayo Clinic, Rochester, MN, 2Quantitative Health Sciences, Mayo Clinic, Rochester, MN, 3Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN

    *Purpose: There are many potential infections post-transplant, with influenza as the most common vaccine-preventable infection the first 5 years post-transplant. Despite effective vaccines, uptake is…
  • 2022 American Transplant Congress

    Non-Invasive Assessment of Hepatic Ischemia-Reperfusion Injury Using Dynamic Contrast Enhanced-MRI and T2 Mapping

    O. C. Rodriguez1, J. R. Liggett2, J. Kang2, K. Loh2, Y. Lee1, N. Sang1, B. He1, Y. Cui2, K. Oza2, D. Kwon3, B. Kallakury3, T. Fishbein2, W. Cui2, K. Khan2, C. Albanese1, A. Kroemer2

    1Lombardi Comprehensive Cancer Center and the Center for Translational Imaging, Georgetown University Medical Center, Washington, DC, 2MedStar Georgetown Transplant Institute, Washington, DC, 3Pathology, MedStar Georgetown University Hospital, Washington, DC

    *Purpose: Hepatic ischemia-reperfusion injury (IRI) is a consequence of liver transplantation and hepatectomy that varies in severity and clinical significance. The diagnosis is made based…
  • 2022 American Transplant Congress

    Complete and High-Resolution HLA Typing Improves the Accuracy of Post-Transplant Assessment of De Novo Anti-Donor Immune-Mediated Events

    M. Meneghini1, A. Perona2, E. Crespo3, F. J. Bemelman4, P. M. Reinke5, O. Viklicky6, M. Giral7, O. Bestard1

    1Vall d'Hebron University Hospital, Barcelona, Spain, 2Universitat de Barcelona, Barcelona, Spain, 3Nephrology and Transplantation Laboratory, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain, 4Amsterdam University Medical Centers, Amsterdam, Netherlands, 5Charité Universitätsmedizin, Berlin, Germany, 6Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic, 7Nantes Université, Inserm, CHU Nantes, Nantes, France

    *Purpose: High-resolution (HR) HLA typing using NGS technology has shown to improve the accuracy of assessing donor-recipient compatibility and characterization of pre-transplant anti HLA antibodies…
  • 2022 American Transplant Congress

    Excellent Long-Term Outcome of ABO-Incompatible Living Kidney Transplantation by Reduced-Session of Plasmapheresis of Desensitization Protocol

    Y. Ishiyama1, K. Tanabe2, T. Kanzawa2, K. Unagami2, H. Ishida2, T. Takagi2

    1Urology, Tokyo Women's Medical University Medical Center East, Arakawa, Japan, 2Tokyo Women's Medical University, Tokyo, Japan

    *Purpose: Plasmapheresis (PE) is applied to ABO-incompatible living kidney transplantation (ABOi-LKT) in order to remove ABO blood type antibody to obtain the appropriate target levels.…
  • 2022 American Transplant Congress

    Long-Term Outcomes of Liver Transplantation (LT) Using Grafts from Donors with Active and Chronic Hepatitis B Virus (HBV) Infection; Multi-Center Cohort Study

    S. Suh1, S. Gang2, Y. Choi2, S. Hong2, N. Yi2, K. Lee2, K. Suh2

    1Chung-Ang University, Seoul, Korea, Republic of, 2Seoul National University, Seoul, Korea, Republic of

    *Purpose: Liver grafts from donors with hepatitis B infection contributed to expand the donor pool under the Hepatitis B immunoglobulin (HBIG) and antiviral agents (NA:…
  • 2022 American Transplant Congress

    Tissue Engineering Scaffolds for Minimally Invasive Immunosurveillance of Acute Cellular Graft Rejection

    R. R. Urie1, D. Farris2, A. Morris1, E. Lombard1, J. Z. Li3, D. Goldstein2, L. Shea1

    1Biomedical Engineering, University of Michigan, Ann Arbor, MI, 2Internal Medicine, University of Michigan, Ann Arbor, MI, 3Human Genetics, University of Michigan, Ann Arbor, MI

    *Purpose: As there is no assay to predict the risk of acute cellular allograft rejection (ACAR), clinicians rely on protocol graft biopsy and aggressive, one-size-fits-all…
  • 2022 American Transplant Congress

    Long-Term Outcomes of Crossmatch Positive Simultaneous Liver Kidney Transplants in the United States

    S. Riad1, E. Aby1, S. Jackson2, P. Nguyen3, N. Lim1, J. Lake1

    1Medicine, University of Minnesota, Minneapolis, MN, 2Mhealth-Fairview, Minneapolis, MN, 3Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: The long-term results of crossmatch positive (XM+) simultaneous liver-kidney (SLK) transplants are conflicting. We examined the association between crossmatch (XM) status and SLK outcomes…
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