2022 American Transplant Congress
Induction Immunosuppression in ABO-Incompatible Liver Transplant Recipients
1Keck Medicine of USC, Los Angeles, CA, 2Keck School of Medicine, Los Angeles, CA
*Purpose: ABO-incompatible (ABO-i) liver transplantation (LT) has been associated with an increased risk of AMR, as well as poor patient and graft survival. With advances…2022 American Transplant Congress
Knowledge Gaps and Perceptions of Liver Disease and Liver Transplant Referral Serve as Barriers to Transplant Among Primary Care Providers in Non-Urban America
*Purpose: The path to liver transplant (LTX) typically begins with primary care providers(PCPs), and is dependent on timely referral to transplant centers. The referral patterns…2022 American Transplant Congress
Predictors of Delayed Kidney Graft Function Following Combined Liver and Kidney Transplantation
*Purpose: Combined liver and kidney transplantation (CLKT) improves the survival in liver transplant recipients with renal dysfunction. However, kidney DGF (kDGF) still represents a common…2022 American Transplant Congress
Pre-Emptive Rituximab Use for Epstein-Barr Virus (EBV) Viremia in Cardiothoracic Solid Organ Transplant Recipients
University of Chicago Medicine, Chicago, IL
*Purpose: EBV viremia is associated with potentially life-threatening post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation. The utility of rituximab for treating EBV viremia in…2022 American Transplant Congress
High-Throughput Immune Synapse Detection as a Tool for the Measurement of T Cell Alloreactivity in Humans
University Health Network, Toronto, ON, Canada
*Purpose: Accurate measurement of T cell alloreactivity may allow prediction of graft outcome and the selection of patients for immunosuppression optimization. Current technologies cannot reliably…2022 American Transplant Congress
Sirolimus Use Is Associated With An Improved Immune Response To Covid-19 Vaccination In Kidney Transplant Recipients
*Purpose: Kidney transplant recipients (KTRs) are highly vulnerable to severe COVID-19, however are poorly protected by vaccination. Additional vaccine doses have achieved limited improvements in…2022 American Transplant Congress
Exploring Individual Optimal Immunosuppression Management According to the Oncological Risk in Liver Transplanted Patients with Hepatocellular Carcinoma
*Purpose: Post-Liver transplant (LT) immunosuppression management is the only modifiable factor to prevent hepatocellular carcinoma (HCC) recurrence; however, the impact of immunosuppression on the HCC…2022 American Transplant Congress
Incidence of De Novo Donor Specific Antibodies After Early Steroid Withdrawal in Kidney Transplant Recipients
Temple University Hospital, Philadelphia, PA
*Purpose: Early steroid withdrawal (ESW) regimens may lead to the formation of de novo donor-specific antibodies (dnDSA) post-kidney transplant, which increases the risk of antibody-mediated…2022 American Transplant Congress
Abnormal B Cell Profile Associated with Inadequate Antibody Response to MRNA SARS-COV-2 Vaccine Can Be Overcome with a Third Vaccine Dose in Adolescent Kidney Transplant Recipients
Pediatrics, UCSD Rady Children's, San Diego, CA
*Purpose: mRNA SARS-CoV-2 vaccines are highly efficacious in the general population but have shown a diminished response in immunosuppressed adolescent kidney allograft recipients. We investigated…2022 American Transplant Congress
Selective CD28 Blockade Impacts T Cell Differentiation During Hematopoietic Reconstitution Following Lymphodepletion
*Purpose: Costimulation blockade targeting the CD28 pathway provides improved long-term transplant survival without the nephrotoxicity of calcineurin inhibitors. However, treatment with the CTLA-4Ig fusion protein…
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