ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Simultaneous Liver/ Kidney Transplant Reduces Both Donor Specific and Non-Donor Specific HLA Antibodies

    X. Zhang, S. Wisel, I. Kim, S. Jordan

    Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: Kidney allografts can be transplanted across strong donor specific antibody (DSA) barriers in simultaneous liver/kidney transplant (SLK) recipients. It is suggested that preformed DSAs…
  • 2022 American Transplant Congress

    Sirolimus Use Is Associated With An Improved Immune Response To Covid-19 Vaccination In Kidney Transplant Recipients

    G. B. Perkins1, M. Tunbridge2, T. Salehi2, C. Chai1, C. M. Hope1, P. Garcia-Valtanen1, J. J. Singer3, P. R. Hurtado2, S. C. Barry1, B. Grubor-Bauk1, P. Hissaria2, S. J. Chadban3, P. Coates1

    1University of Adelaide, Adelaide, Australia, 2Royal Adelaide Hospital, Adelaide, Australia, 3Royal Prince Alfred Hospital, Sydney, Australia

    *Purpose: Kidney transplant recipients (KTRs) are highly vulnerable to severe COVID-19, however are poorly protected by vaccination. Additional vaccine doses have achieved limited improvements in…
  • 2022 American Transplant Congress

    Predictors of Delayed Kidney Graft Function Following Combined Liver and Kidney Transplantation

    P. Vincenzi1, J. Gaynor2, R. Vianna3, G. Ciancio3

    1General Surgery, Ospedali Riuniti Marche Nord, Pesaro, Italy, 2General Surgery, Miami Transplant Institute, Miami, FL, 3Transplant Surgery, Miami Transplant Institute, Miami, FL

    *Purpose: Combined liver and kidney transplantation (CLKT) improves the survival in liver transplant recipients with renal dysfunction. However, kidney DGF (kDGF) still represents a common…
  • 2022 American Transplant Congress

    Locoregional Therapy and Long-Term Post-Transplant Outcomes for HCC Liver Transplant Recipients

    T. Ishaque, S. R. Weeks, A. Kolarich, J. Ruck, J. Garonzik-Wang, D. Segev, A. Massie, B. King

    Johns Hopkins Medical Institutions, Baltimore, MD

    *Purpose: In last decade, locoregional therapy (LRT) have been widely used to downstage HCC patients in order to qualify for liver transplantation. Large-scale direct comparisons…
  • 2022 American Transplant Congress

    Comparison of Outcomes of Covid-19 Between Fully Vaccinated and Unvaccinated Kidney Transplant Recipients and According to the Type of M-RNA Vaccine

    F. Villanego1, M. Crespo2, V. Lopez3, S. Zarraga4, F. Oppenheimer5, L. Llinas2, A. Andres6, C. Diaz7, M. Ruiz8, F. Moreso9, A. Rodriguez-Benot10, I. Beneyto11, S. Cabello12, C. Jimenez13, C. Canal14, M. Molina15, J. Pascual6, A. Mazuecos1

    1Department of Nephrology, Hospital Puerta del Mar, Cadiz, Spain, 2Department of Nephrology, Hospital del Mar, Barcelona, Spain, 3Department of Nephrology, Hospital Regional de Malaga, Malaga, Spain, 4Department of Nephrology, Hospital de Cruces, Baracaldo, Spain, 5Department of Nephrology, Hospital Clinic, Barcelona, Spain, 6Department of Nephrology, Hospital 12 de Octubre, Madrid, Spain, 7Department of Nephrology, Hospital Central de Asturias, Oviedo, Spain, 8Department of Nephrology, Hospital Virgen de las Nieves, Granada, Spain, 9Department of Nephrology, Hospital Vall d'Hebron, Barcelona, Spain, 10Department of Nephrology, Hospital Reina Sofia, Cordoba, Spain, 11Department of Nephrology, Hospital La Fe, Valencia, Spain, 12Department of Nephrology, Hospital Son Espases, Palma de Mallorca, Spain, 13Department of Nephrology, Hospital La Paz, Madrid, Spain, 14Department of Nephrology, Fundacion Puigvert, Barcelona, Spain, 15Department of Nephrology, Hospital Germans Trias i Pujol, Badalona, Spain

    *Purpose: The evidence regarding the clinical effectiveness of COVID-19 vaccination in kidney transplant (KT) recipients is limited so far. Our purpose is to analyze the…
  • 2022 American Transplant Congress

    Impact of Low Dose Donor-Specific HLA Antibodies in Living and Deceased Donor Kidney Transplantation

    H. Lee1, I. Sun2, C. Yang1, B. Chung1

    1Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's hospital, Seoul, Korea, Republic of, 2Division of Nephrology, Department of Internal Medicine., Presbyterian Medical Center, Jeonju, Korea, Republic of

    *Purpose: The prognostic value of low level preformed donor-specific antibodies (DSA) remains controversial for kidney transplantation. The aim of the present study was to investigate…
  • 2022 American Transplant Congress

    Gm2a Regulates Memory Cd8+ T Cell Activation and Differentiation

    K. P. Tong1, K. M. Baecher2, C. R. Hartigan1, M. Ford3

    1Emory University Transplant Center, Emory University, Atlanta, GA, 2Department of Surgery, Emory University, Atlanta, GA, 3Emory University, Atlanta, GA

    *Purpose: In a clinical trial, patients who underwent kidney transplantation and were subsequently stable off tacrolimus immunosuppression exhibited increased Gm2a transcript in PBMC relative to…
  • 2022 American Transplant Congress

    Human PBMC-Transferred Murine MHC Class I/II-Deficient NOG Mice Enable Long-Term Evaluation of Human Immune Responses to Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Sheets

    R. Matsumoto

    Center for Immune Therapeutics and Diagnosis, Juntendo University, Tokyo, Japan

    *Purpose: Transplantation of cardiomyocytes sheets derived from allogenic human induced pluripotent stem cells (hiPS-CMs) hold great promise in generating new functional myocardium in situ. However,…
  • 2022 American Transplant Congress

    Xenogeneic Cross-Circulation Supports Ex Vivo Human Livers for 24 Hours

    W. K. Wu1, R. Ukita2, Y. J. Patel2, I. A. Ziogas3, M. Cortelli2, M. Mentz2, J. R. Talackine2, S. A. Francois2, N. L. Cardwell2, J. W. Stokes2, S. P. Alexopoulos3, M. Bacchetta2

    1Hepatobiliary Surgery and Liver Transplantation; Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, 2Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, 3Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Despite increasing use of machine perfusion as an organ preservation and rescue technique in liver transplantation, significant organ shortages and waitlist mortality highlight a…
  • 2022 American Transplant Congress

    Pd-1 Licenses Activated Treg for Lymphatic Migration

    W. Piao1, L. Li1, V. Saxena1, K. Hippen2, M. Shirkey1, B. Blazar2, I. Lape3, y. zhang3, J. Bromberg1

    1Surgery, University of Maryland, Baltimore, MD, 2University of Minnesota, Minneapolis, MN, 3Harvard Medical School, Boston, MA

    *Purpose: In addition to serving as fluid conduits, lymphatic vessels are critical portals for immune cell migration. Lymphatic endothelial cells (LECs) constitutively express high levels…
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