ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Vimentin Inhibition Improves Post-Transplant Survival in a Mouse Renal Transplant Model

    R. Lopez-Soler1, Z. Zhang2, H. Chin3, J. Wang4, K. Ridge5

    1Albany Medical College, Albany, NY, 2Microsurgery Core, Comprehensive Transplant Center, Northwestern University, Feinberg School of Medicine, Chicago, IL, 3Molecular and Cellular Physiology, Albany Medical College, Albany, NY, 4Microsurgery Core, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL, 5Northwestern Univesity, Feinberg School of Medicine, Chicago, IL

    *Purpose: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…
  • 2019 American Transplant Congress

    Towards Human Leukocyte Antigen Immunogenicity Assessment at the Individual Patient Level

    H. Copley1, H. McDowell2, D. Pinelli2, A. R. Tambur2, V. Kosmoliaptsis1

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom, 2Department of Surgery, Feinberg School of Medicine, Comprehensive Transplant Center, Northwestern University, Chicago, IL

    *Purpose: Allorecognition of donor HLA and induction of humoral alloimmunity is a major cause of graft loss after solid-organ transplantation. Current approaches to study molecular…
  • 2019 American Transplant Congress

    Organ Procurement Organization Performance is Not Related to Educational Spending

    J. P. Roberts1, J. Bragg-Gresham2, P. Held3

    1Univ of California-San Francisco, San Francisco, CA, 2Nephrology, University of Michigan, Ann Arbor, MI, 3Stanford University, Stanford, CA

    *Purpose: We examined the educational spending by OPOs in relationship to OPO performance metrics.*Methods: Data sources: OPO Cost Reports (CMS 216-94 Form), SRTR OPO Specific…
  • 2019 American Transplant Congress

    Human Neutrophil Function against Pathogens in Solid Organ and Stem Cell Transplant Recipients

    N. Barros, N. Alexander, Z. Dagher, S. Knooihuizen, A. Viens, A. R. Hopke, D. Irimia, M. K. Mansour

    Transplant Infectious Diseases, Massachusetts General Hospital, Boston, MA

    *Purpose: The effects of solid organ (SOT) and allogeneic stem cell transplantation (SCT) on the neutrophil function is not well described. In this study, we…
  • 2019 American Transplant Congress

    Impact of Previous Hepatic Resection on the Outcome of Liver Transplantation: A Case-Control Analysis

    M. Serenari, M. Paterno, A. D. Pinna, M. Ravaioli, E. Prosperi, M. Del Gaudio, C. Zanfi, V. Bertuzzo, G. Frascaroli, M. Cescon

    University of Bologna, Bologna, Italy

    *Purpose: The aim of this study was to investigate the impact of HR on the outcome of LT.*Methods: Data of patients treated by LT between…
  • 2019 American Transplant Congress

    Pathologic Vascular Invasion Correlates with Worse Outcome in Hepatoblastoma Patients Treated with Liver Transplantation – A Hepatoblastoma Transplant Consortium Study

    T. H. Malik1, H. Zhu2, T. Ha3, S. Commander4, C. Trautz5, R. Sindhi5, S. Kim6, K. Vakili6, N. Vachharajani7, W. Chapman7, A. Griesemer8, M. Martinez8, J. A. Goss9, S. Vasudevan10

    1Baylor College of Medicine, Houston, TX, 2Texas Children's Hospital, Houston, TX, 3Department of Surgery, Baylor College of Medicine, Houston, TX, 4Department of Surgery, Duke University School of Medicine, Durham, NC, 5Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 6Department of Surgery, Boston Children's Hospital, Boston, MA, 7Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, 8Department of Surgery, NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, NY, 9Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, 10Department of Pediatric Surgery, Texas Children's Hospital, Houston, TX

    *Purpose: Orthotopic liver transplant (OLTx) is the most common method to treat unresectable hepatoblastoma (HB) in children. There is limited data focusing on the outcomes…
  • 2019 American Transplant Congress

    Pediatric Liver Transplantation for Metabolic Disorders without Intrinsic Liver Disease: A 25 Year Experience

    P. Vuong, L. Lee, N. Mineyev, S. Conlon, R. Shetty, W. Concepcion, C. A. Bonham, A. Gallo, T. Pham, S. Busque, M. L. Melcher, G. M. Enns, C. O. Esquivel

    Stanford University Medical Center, Palo Alto, CA

    *Purpose: Liver transplantation (LT) for acute and chronic end-stage-liver-disease is a well-accepted therapy in pediatrics. However, for children with metabolic disorders (MD) without intrinsic liver…
  • 2019 American Transplant Congress

    Complete Robotic-Assisted Kidney Transplantation: Our Initial Experience

    A. Khan, C. Bhati, T. Reichman, A. Cotterell, D. Kumar, G. Gupta, L. Kamal, A. King, A. Sharma, M. Levy

    VCU Medical Center, Richmond, VA

    *Purpose: Kidney transplantation is the standard treatment for patients with ESRD. Very limited advancement has been made in its surgical aspects. Minimal invasive approach for…
  • 2019 American Transplant Congress

    Ex Vivo Assessment of Marginal Human Kidneys Using Computed Tomography

    M. K. Harris1, J. R. DiRito2, H. Liu3, N. Boutagy3, C. Liu4, S. Hosgood2, D. Mulligan1, M. L. Nicholson2, A. Sinusas3, D. Haakinson1, G. T. Tietjen1

    1Surgery, Yale School of Medicine, New Haven, CT, 2Surgery, University of Cambridge, Cambridge, United Kingdom, 3Yale Translational Research Imaging Center, New Haven, CT, 4Radiology, Yale School of Medicine, New Haven, CT

    *Purpose: Thousands of ‘marginal’ organs are discarded each year despite a severe organ shortage. This has motivated development of new technologies, such as ex vivo…
  • 2019 American Transplant Congress

    Breaking Concepts: 10-year Follow-Up of the Everolimus versus Azathioprine Heart Transplant Multi-National Study

    J. A. Kobashigawa1, R. Starling2, E. Passano1, P. Bernhardt3, B. Azarbal1, R. Cheng1, F. Esmailian1, K. Khush4, D. Mancini5, J. Patel1, T. Sato1, S. Varnous6

    1Smidt Heart Institute at Cedars-Sinai, Los Angeles, CA, 2Cleveland Clinic, Cleveland, OH, 3Novartis Pharmaceuticals, Basel, Switzerland, 4Stanford University, Palo Alto, CA, 5Mount Sinai, New York, NY, 6APHP, Pitié‐Salpétrière, Sorbonne University, Paris, France

    *Purpose: This study is the 10-year follow-up of a randomized double-blind prospective trial that compared everolimus (1.5 mg or 3 mg) to azathioprine. In this…
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