ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Mycophenolate Mofetil versus Azathioprine in Kidney Transplant Recipients on Steroid-Free Low-Dose Cyclosporine Immunosuppression: The ATHENA Trial

    P. Cravedi1, P. Ruggenenti2, E. Gotti2, A. Plati2, S. Sandrini3, N. Bossini3, F. Citterio4, E. Minetti5, D. Montanaro6, R. Tardanico3, E. Sabadini2, F. Gaspari7, A. Villa7, F. Peraro7, G. Remuzzi7

    1Mount Sinai, New York, NY, 2ASST Ospedale Papa Giovanni XXIII, Bergamo, Italy, 3ASST degli Spedali Civili, Brescia, Italy, 4Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy, 5ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, 6Presidio Ospedaliero Universitario Santa Maria della Misericordia, Udine, Italy, 7Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy

    *Purpose: Registration trials using old sandimmune formulation of cyclosporine (CsA) led to the general idea that Mycophenolate Mofetil (MMF) prevents acute cellular rejection (ACR) more…
  • 2019 American Transplant Congress

    Platelets Stimulate Liver Regeneration in a 30% Partial Liver Transplantation Model in Rat

    C. Liang, K. Takahashi, T. Oda, N. Ohkohchi

    University of Tsukuba, Tsukuba, Japan

    *Purpose: Thirty years after the first living donor liver transplantation (LDLT), this technique has been widely recognized as the golden standard in treatment of end-stage…
  • 2019 American Transplant Congress

    Blood Profiling Reflects a Significant Down-Regulation in Oxidative Phosphorylation Following Renal Transplantation with DCD and AKI Allografts

    S. Walker1, L. Cox2, C. Langefeld2, B. Freedman2, A. Farney2, J. Rogers2, C. Jay2, R. Stratta2, G. Orlando2

    1Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, 2Wake Forest Baptist Medical Center, Winston Salem, NC

    *Purpose: The human kidney transplant (KT) patient provides a unique and compelling in situ model system to study molecular events that underlie graft recovery following…
  • 2019 American Transplant Congress

    Utilization of Hepatitis C Donors is Safe and Cost Effective

    J. Shaw, D. Reino, N. Kapila, K. Al Khalloufi, S. Ebaid, S. Rhazouani, X. Zervos, J. Vanatta, N. Agrawal

    Cleveland Clinic, Weston, FL

    *Purpose: The use of hepatitis C (hep C) positive donors has become increasingly attractive with the advent of improved curative pharmacologic treatments. As a result…
  • 2019 American Transplant Congress

    Vimentin Inhibition Improves Post-Transplant Survival in a Mouse Renal Transplant Model

    R. Lopez-Soler1, Z. Zhang2, H. Chin3, J. Wang4, K. Ridge5

    1Albany Medical College, Albany, NY, 2Microsurgery Core, Comprehensive Transplant Center, Northwestern University, Feinberg School of Medicine, Chicago, IL, 3Molecular and Cellular Physiology, Albany Medical College, Albany, NY, 4Microsurgery Core, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL, 5Northwestern Univesity, Feinberg School of Medicine, Chicago, IL

    *Purpose: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…
  • 2019 American Transplant Congress

    Towards Human Leukocyte Antigen Immunogenicity Assessment at the Individual Patient Level

    H. Copley1, H. McDowell2, D. Pinelli2, A. R. Tambur2, V. Kosmoliaptsis1

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom, 2Department of Surgery, Feinberg School of Medicine, Comprehensive Transplant Center, Northwestern University, Chicago, IL

    *Purpose: Allorecognition of donor HLA and induction of humoral alloimmunity is a major cause of graft loss after solid-organ transplantation. Current approaches to study molecular…
  • 2019 American Transplant Congress

    Organ Procurement Organization Performance is Not Related to Educational Spending

    J. P. Roberts1, J. Bragg-Gresham2, P. Held3

    1Univ of California-San Francisco, San Francisco, CA, 2Nephrology, University of Michigan, Ann Arbor, MI, 3Stanford University, Stanford, CA

    *Purpose: We examined the educational spending by OPOs in relationship to OPO performance metrics.*Methods: Data sources: OPO Cost Reports (CMS 216-94 Form), SRTR OPO Specific…
  • 2019 American Transplant Congress

    Human Neutrophil Function against Pathogens in Solid Organ and Stem Cell Transplant Recipients

    N. Barros, N. Alexander, Z. Dagher, S. Knooihuizen, A. Viens, A. R. Hopke, D. Irimia, M. K. Mansour

    Transplant Infectious Diseases, Massachusetts General Hospital, Boston, MA

    *Purpose: The effects of solid organ (SOT) and allogeneic stem cell transplantation (SCT) on the neutrophil function is not well described. In this study, we…
  • 2019 American Transplant Congress

    Impact of Previous Hepatic Resection on the Outcome of Liver Transplantation: A Case-Control Analysis

    M. Serenari, M. Paterno, A. D. Pinna, M. Ravaioli, E. Prosperi, M. Del Gaudio, C. Zanfi, V. Bertuzzo, G. Frascaroli, M. Cescon

    University of Bologna, Bologna, Italy

    *Purpose: The aim of this study was to investigate the impact of HR on the outcome of LT.*Methods: Data of patients treated by LT between…
  • 2019 American Transplant Congress

    Pathologic Vascular Invasion Correlates with Worse Outcome in Hepatoblastoma Patients Treated with Liver Transplantation – A Hepatoblastoma Transplant Consortium Study

    T. H. Malik1, H. Zhu2, T. Ha3, S. Commander4, C. Trautz5, R. Sindhi5, S. Kim6, K. Vakili6, N. Vachharajani7, W. Chapman7, A. Griesemer8, M. Martinez8, J. A. Goss9, S. Vasudevan10

    1Baylor College of Medicine, Houston, TX, 2Texas Children's Hospital, Houston, TX, 3Department of Surgery, Baylor College of Medicine, Houston, TX, 4Department of Surgery, Duke University School of Medicine, Durham, NC, 5Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 6Department of Surgery, Boston Children's Hospital, Boston, MA, 7Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, 8Department of Surgery, NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, NY, 9Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, 10Department of Pediatric Surgery, Texas Children's Hospital, Houston, TX

    *Purpose: Orthotopic liver transplant (OLTx) is the most common method to treat unresectable hepatoblastoma (HB) in children. There is limited data focusing on the outcomes…
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