Abstracts Archive - Page 65 of 1683 - ATC Abstracts

2022 American Transplant Congress
Comparing Disparities in Access to First and Re-Kidney Transplantation Among Hispanic and Black Adults in the United States
S. Sandal¹, J. Ahn², V. Thompson³, T. Purnell⁴, M. Cantarovich⁵, D. Segev³, M. McAdams DeMarco³
¹McGill University, Montreal, QC, Canada, ²SOM, Johns Hopkins University, Baltimore, MD, ³Johns Hopkins University, Baltimore, MD, ⁴Johns Hopkins School of Medicine, Baltimore, MD, ⁵McGill University Health Ctr, Montreal, QC, Canada
*Purpose: There are significant racial/ethnic disparities in access to solid organ transplantation; lack of education and familiarity with the transplant process are postulated contributors. Among…
2022 American Transplant Congress
Donor-Derived IL-33 Plays a Critical Role in Lung Allograft Acceptance
Y. Guo¹, Z. Mei¹, M. Khalil¹, D. Li¹, A. Banerjee¹, A. Gelman², D. Kreisel², A. Krupnick¹
¹Department of Surgery, University of Maryland, Baltimore, Baltimore, MD, ²Washington University School of Medicine in St Louis, Saint Louis, MO
*Purpose: IL-33 is considered an alarmin secreted in response to tissue damage. While it is elaborated by the lung allograft as part of ischemia-reperfusion injury…
2022 American Transplant Congress
When Pancreata Fly: Excellent Results from Long Distance Imported Pancreas Allografts
N. Owen-Simon, G. Dube, P. Sandoval, L. Ratner, K. McCune
Department of Surgery, Columbia University College of Physicians and Surgeons, New York, NY
*Purpose: To address long waitlist times and increase pancreas transplantation in a competitive donor service area, our center has adopted a protocol for long distance…
2022 American Transplant Congress
Cd80 on Effector T Cell Binds Pd-l1 on Lymphatic Endothelial Cells to Fine Tune Migration
W. Piao¹, V. Saxena¹, L. Li¹, K. Hippen², Y. Zhang², B. Blazar², I. Lape³, L. Riella³, J. Bromberg¹
¹Surgery, University of Maryland, Baltimore, MD, ²University of Minnesota, Minneapolis, MN, ³Harvard Medical School, Boston, MA
*Purpose: Antigen presenting cell (APC) CD80 trans-binds CD28 and CTLA4 on T cells, boosting or inhibiting immunity, respectively. CD80 has another ligand, Programmed Death-1 Ligand…
2022 American Transplant Congress
Cost-Effectiveness of Transplanting Hepatitis C Donor Hearts Into Hepatitis C Uninfected Recipients
A. R. Gandhi¹, A. E. Woolley², L. R. Baden², M. M. Givertz², M. L. Jones¹, J. Kim³, H. R. Mallidi², M. R. Mehra², A. M. Neilan¹
¹Massachusetts General Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, MA, ³Harvard T.H. Chan School of Public Health, Boston, MA
*Purpose: To examine the clinical impact and cost-effectiveness of hepatitis C viremic (HCV+) heart organ donation in the United States.*Methods: We used a microsimulation model…
2022 American Transplant Congress
Optimization of Human Liver Organoid Model for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis
Y. Park¹, D. Thadasina¹, K. Isidan¹, K. J. Lopez¹, A. Cross-Najafi¹, P. Li¹, H. Francis², G. Alpini², W. Zhang¹, B. Ekser¹
¹Surgery, Indiana University School of Medicine, Indianapolis, IN, ²Division of Gastroenterology & Hepatology, Indiana University School of Medicine, Indianapolis, IN
*Purpose: The aim of our project is to develop an in vitro 3D human liver organoid (3D-HLO) model for studying nonalcoholic fatty liver disease (NAFLD)…
2022 American Transplant Congress
Area Deprivation Index is Associated with Worse Patient Survival Following Adult Liver Transplantation
J. Hendele¹, J. Perkins², J. Nichols³, A. Dick¹
¹Division of Transplant Surgery, Department of Surgery, University of Washington, Seattle, WA, ²Clinical and Bio-Analytics Transplant Laboratory (CBATL), University of Washington, Division of Transplant Surgery, Department of Surgery, Seattle, WA, ³School of Medicine, University of Washington, Seattle, WA
*Purpose: Area Deprivation Index (ADI) has been utilized as a granular measure of local socioeconomic status for nearly two decades. This study is the first…
2022 American Transplant Congress
Human PBMC-Transferred Murine MHC Class I/II-Deficient NOG Mice Enable Long-Term Evaluation of Human Immune Responses to Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Sheets
R. Matsumoto
Center for Immune Therapeutics and Diagnosis, Juntendo University, Tokyo, Japan
*Purpose: Transplantation of cardiomyocytes sheets derived from allogenic human induced pluripotent stem cells (hiPS-CMs) hold great promise in generating new functional myocardium in situ. However,…
2022 American Transplant Congress
A2/A2B to B Kidney Transplantation Outcomes: A Single-Center 5 Year Experience
A. El Chediak, S. Shawar, M. Fallahzadeh, I. Feurer, S. Rega, J. L. Triozzi, D. Shaffer
Vanderbilt University Medical Center, Nashville, TN
*Purpose: The new kidney allocation system (KAS) instituted in 2014 allowed organ procurement organizations to allocate A2/A2B to B candidates preferentially was meant to improve…
2022 American Transplant Congress
Differences in Post-Liver Transplant Hospitalizations by Patient Race
K. Ross-Driscoll¹, R. Lynch¹, J. Wedd², R. Patzer¹
¹Emory University, Atlanta, GA, ²Virginia Commonwealth University, Richmond, VA
*Purpose: Hospital admissions after liver transplant are common, costly, and associated with poor outcomes. While survival disparities are well-documented for Black liver recipients, little is…