Abstracts Archive - Page 648 of 1683 - ATC Abstracts

2019 American Transplant Congress
Inhibition of Sialidase Activity and Galectin Binding Reduces Xenogeneic Neutrophil-Endothelial Adhesion
B. M. Cerel¹, B. M. French², D. G. Harris², C. Laird², L. Burdorf¹, X. Cheng², C. Feng³, A. S. Cross⁴, S. E. Goldblum⁴, G. R. Vasta³, R. N. Pierson III¹, A. M. Azimzadeh¹
¹Deparment of Surgery, Massachusetts General Hospital, Boston, MA, ²Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, ³Department of Microbiology and Immunology, and Institute of Marine and Environmental Technology, University of Maryland School of Medicine, Baltimore, MD, ⁴Department of Medicine Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD
*Purpose: Immediate neutrophil sequestration occurs despite genetic modifications (Gal-a-1-3 galactosyl transferase knock out; human CD46 complement regulatory gene addition) to pig donor organs. Sialic acids…
2019 American Transplant Congress
Protective Effect of Ischemic-Free Liver Transplantation Technique on Distant Multiple Organ Function
L. Wang¹, Z. Guo¹, L. Yang², W. Xiong², S. Huang¹, T. Zhang², Y. Tang¹, Z. Zhang¹, Z. Zhu¹, C. Zhu¹, X. He¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Department of Anesthesiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: Hypothermia, hypoxia and ischemia-reperfusion injury (IRI) in standard liver transplantation (SLT) are the main factors that affect graft function and cause damage to remote…
2019 American Transplant Congress
Obese Simultaneous Pancreas And Kidney Transplant Recipients In Type 2 Diabetes Have Similar Risks Of Pancreas Failure As Non-obese
T. Alhamad¹, K. Espinoza¹, J. R. Wellen¹, S. Chang¹, D. C. Brennan², K. L. Lentine³
¹Washinton University in St. Louis, St. Louis, MO, ²Johns Hopkins University, Baltimore, MD, ³Saint Louis University, St. Louis, MO
*Purpose: In October 2014, United Network for Organ Sharing (UNOS) implemented criteria for simultaneous pancreas and kidney transplant (SPKT) in patients with c-peptide 2 >…
2019 American Transplant Congress
Donor-Derived Cell-Free DNA for Surveillance in Simultaneous Pancreas and Kidney Transplant Recipients, Can We Extrapolate from Kidney Transplant Alone?
O. K. Olaitan¹, S. Loeb¹, E. Hetterman², V. Peev¹, S. Saltzberg¹, M. Hertl¹, S. Dholakia²
¹Rush University Medical Center, Chicago, IL, ²CareDx, Brisbane, CA
*Purpose: Assessment and identification of early organ injury in Simultaneous Pancreas and Kidney (SPK) patients has clear clinical utility. This analysis was performed to establish…
2019 American Transplant Congress
Utilization of LCP-Tacrolimus (ENVARSUS XR) in Simultaneous Pancreas and Kidney (SPK) Transplant Recipients
J. Torabi, A. Campbell, E. Akalin, M. Ajaimy, Y. Azzi, C. Pynadath, L. Liriano-Ward, J. P. Rocca, J. A. Graham
Montefiore Medical Center, Bronx, NY
*Purpose: The use of extended release tacrolimus (LCPT) allows for slow release of drug and once-daily dosing in transplant recipients. The improved bioavailability and decreased…
2019 American Transplant Congress
Comparison of Portal vs Systemic Venous Drained Pancreas Transplantation Alone Matched by Propensity Score Analysis
F. Vistoli, N. Napoli, F. Palumbo, E. Kauffmann, V. Perrone, S. Iacopi, C. Lombardo, G. Amorese, P. Marchetti, U. Boggi
Pancreas and Kidney Transplantation Center, University of Pisa, Pisa, Italy
*Purpose: Portal drainage (PD) of pancreas grafts has been associated with improved metabolic profile and fewer rejection episodes than systemic drainage (SD). These advantages would…
2019 American Transplant Congress
Thymoglobulin Efficacy: The Role of Dosing on Viral Infection and Rejection in Pancreas Transplantation
H. Sarumi, B. Johnson, S. Jackson, S. Hogan, J. Fisher, S. Riad, R. Kandaswamy, T. Pruett
Transplant Surgery, University of Minnesota Medical Center, Minneapolis, MN
*Purpose: While T-cell depletion therapy is standard practice for induction in pancreas transplantation, little data exists to help determine dosing and its impact on efficacy…
2019 American Transplant Congress
Outcomes Of Simultaneous Pancreas/kidney Transplantation In Bmi Extremes
A. Al-Kurd, M. Safwan, D. Kim, M. Abouljoud, S. Nagai
Henry Ford Hospital, Detroit, MI
*Purpose: To assess the outcomes of simultaneous pancreas/kidney (SPK) transplantation in high and low BMI patients.*Methods: A retrospective analysis of the United Network for Organ…
2019 American Transplant Congress
What Are Factors That Can Influence The High Immunological Graft Loss Rate In Young Pancreas Transplant Recipients
A. C. Gruessner, J. Renz, S. Saggi, R. W. Gruessner
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: Pancreas transplants (tx) are increasingly performed in older patients with type 1 diabetes mellitus. This trend may be explained by the significantly higher immunologic…
2019 American Transplant Congress
Kidney Allograft Survival Among Kidney-pancreas Recipients Compared To Solitary Kidney Recipients: A Mate Analysis Of The Unos/optn Database
O. K. Serrano¹, R. Kandaswamy², E. B. Finger²
¹Hartford Hospital, Hartford, CT, ²Surgery, University of Minnesota, Minneapolis, MN
*Purpose: Deceased donor kidney allocation policies differ between solitary organs and combined transplants. The estimated waiting time for a kidney as part of a simultaneous…