Abstracts Archive - Page 64 of 1683 - ATC Abstracts

2022 American Transplant Congress
Transjugular Intrahepatic Portosystemic Shunt Placement is Associated with Increased All-Cause and Cardiac Mortality in Those Undergoing Liver Transplant for Nonalcoholic Steatohepatitis
D. U. Lee¹, J. Han², J. Kwon², K. Chang², G. Fan², K. Lee¹, N. Urrunaga³, C. Bhati¹, D. Maluf³, K. Shetty³
¹Department of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, ²Tufts Medical Center, Boston, MA, ³University of Maryland, Baltimore, MD
*Purpose: Since the effect of transjugular intrahepatic portosystemic shunt (TIPS) on post LT outcomes is not well understood, we undertook this analysis of a large…
2022 American Transplant Congress
Characterizing the Landscape of Cancer Risk Following HLA-Incompatible Living Donor Kidney Transplantation
J. D. Motter¹, K. Jackson¹, K. Yu², R. M. Pfeiffer², A. Massie¹, J. Garonzik-Wang³, D. Segev¹, E. A. Engels²
¹Johns Hopkins University, Baltimore, MD, ²National Cancer Institute, Bethesda, MD, ³University of Wisconsin-Madison, Madison, WI
*Purpose: Incompatible living donor kidney transplant recipients (ILDKTr) require desensitization to facilitate transplantation across donor-specific antibody (DSA); however, this substantial upfront immunosuppression may result in…
2022 American Transplant Congress
Xenogeneic Cross-Circulation Supports Ex Vivo Human Livers for 24 Hours
W. K. Wu¹, R. Ukita², Y. J. Patel², I. A. Ziogas³, M. Cortelli², M. Mentz², J. R. Talackine², S. A. Francois², N. L. Cardwell², J. W. Stokes², S. P. Alexopoulos³, M. Bacchetta²
¹Hepatobiliary Surgery and Liver Transplantation; Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, ²Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, ³Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Despite increasing use of machine perfusion as an organ preservation and rescue technique in liver transplantation, significant organ shortages and waitlist mortality highlight a…
2022 American Transplant Congress
Autencoder, a Novel Computational Tool to Score T Cell Clones Demonstrates Biopsy T Cell Clones Are Not Represented in the Peripheral Blood
N. Borcherding, A. Leckie-Harre, H. Wu, B. D. Humphreys, A. F. Malone
Washington University, St Louis, MO
*Purpose: Antibody-mediated rejection (AMR) remains one of the major causes of allograft failure and our understanding of this disease process is poor. The generation and…
2022 American Transplant Congress
Normal Saline vs Electrolyte-a Use Peri- and Post-Operatively in Adult Kidney Transplant Recipients
K. R. Szempruch, A. D. Martschenko, H. Arora, R. Isaak, R. Prasad, P. Serrano
UNC Medical Center, Chapel Hill, NC
*Purpose: 0.9% normal saline (NS) has been used as the standard fluid replacement in kidney transplant recipients (KTRs) to prevent dehydration and to improve renal…
2022 American Transplant Congress
Increase in Exception and Extension Requests for Higher-Urgency Patients Under the New Heart Allocation Policy
J. R. Golbus¹, Y. Ahn², B. K. Nallamothu¹, M. N. Walsh³, D. Zaun², A. Israni², M. Colvin¹
¹University of Michigan, Ann Arbor, MI, ²Hennepin Healthcare Research Institute, Minneapolis, MN, ³Ascension St. Vincent Heart Center, Carmel, IN
*Purpose: In October 2018, a new heart allocation policy was introduced that expanded the number of listing statuses and established a national review board, abolishing…
2022 American Transplant Congress
Ex Vivo Modification of Vascular Allografts Using Immunosuppressive and Anti-Inflammatory Polymers Prevent Rejection via Localized Immunosuppression
H. D. Luo¹, E. M. Siren¹, W. Enns², L. Sim¹, C. Du¹, S. G. Withers¹, J. Choy³, J. N. Kizhakkedathu¹
¹The University of British Columbia, Vancouver, BC, Canada, ²Simon Fraser University, Burnaby, BC, Canada, ³Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada
*Purpose: Classical immunosuppressants lead to systemic immune shutdown, though necessary to mediate transplant rejection, it may lead to various complications. To reduce off-target immunosuppression while…
2022 American Transplant Congress
Impact of a Pharmacist on Transitions and Ambulatory Outcomes in Lung Transplant Recipients
A. Yang, R. McKnight, A. Prom, M. Byrne, R. Evans, C. Doligalski
UNC Health, Chapel Hill, NC
*Purpose: Minimal data exists describing the impact of a pharmacist in transitions of care (TOC) and ambulatory medication management in lung transplant recipients (LTRs). Following…
2022 American Transplant Congress
Mortality in Solid Organ Transplant Recipients with a Pretransplant Cancer Diagnosis
A. Hart¹, R. Pfeiffer², B. Morawski³, C. Lynch⁴, Y. Zeng⁵, K. Pawlish⁶, K. Yu⁷, D. Hurley⁸, E. Engels⁷
¹Hennepin Healthcare, University of Minnesota, Minneapolis, MN, ²Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, ³Cancer Registry of Idaho, Boise, ID, ⁴Epidemiology, University of Iowa, Iowa City, IA, ⁵North Dakota Statewide Cancer Registry, Grand Forks, ND, ⁶New Jersey State Cancer Registry, Trenton, NJ, ⁷Infections and Immunoepidemiology Branch, National Cancer Institute, Bethesda, MD, ⁸University of South Carolina, Columbia, SC
*Purpose: Transplant-associated immunosuppression may cause cancer recurrence in patients with a pretransplant cancer, but little is known about outcomes among these recipients.*Methods: We used data…
2022 American Transplant Congress
De Novo Focal Segmental Glomerulosclerosis in the Kidney Allograft: Association with Alloimmunity Leading to Poor Outcome
J. Leon¹, J. Duong Van Huyen², A. Abderrahmane¹, D. Anglicheau¹, C. Legendre¹, M. Rabant²
¹KIDNEY TRANSPLANTATION, Necker Hospital, Paris, France, ²KIDNEY PATHOLOGY, Necker Hospital, Paris, France
*Purpose: Focal Segmental Glomerulosclerosis (FSGS) can be found de novo (Dn) or as a recurrence in kidney allograft. While FSGS recurrence has been extensively described…