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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Is Repeat Resection for Recurrent Intrahepatic Cholangiocarcinoma Warranted? Outcomes of an International Multicenter Analysis

    M. L. Holzner1, V. Mazzaferro2, M. Droz dit Busset2, L. Aldrighetti3, F. Ratti3, K. Hasegawa4, J. Arita4, G. Sapisochin5, P. Abreu5, W. Schoening6, N. Nevermann6, M. Schmelzle6, J. Pratschke6, S. Florman1, K. Halazun7, M. E. Schwartz1, P. Tabrizian1

    1Recanati/Miller Transplantation Institute, Mount Sinai, New York, NY, 2University of Milan, Milan, Italy, 3San Raffaele Hospital, Milan, Italy, 4University of Tokyo, Tokyo, Japan, 5University of Toronto, Toronto, ON, Canada, 6Charite University, Berlin, Germany, 7Weill Cornell Medical Center, New York, NY

    *Purpose: Recurrence of intrahepatic cholangiocarcinoma (ICC) after liver resection (LR) remains high and optimal therapy for recurrent ICC is challenging. Herein we assess the outcomes…
  • 2022 American Transplant Congress

    Living Donor Kidney Transplant in Recipients with Glomerulonephritis: Donor Recipient Biologic Relationship and Allograft Outcomes

    R. El-Rifai1, R. Spong1, A. Bregman1, K. Swanson1, S. Jackson2, S. Riad1

    1Nephrology, University of Minnesota, Minneapolis, MN, 2MHealth, Minneapolis, MN

    *Purpose: Controversies exist over the impact of donor-recipient biologic relationship on the outcomes of living donor kidney transplant in recipients with glomerulonephritis (GN). The improved…
  • 2022 American Transplant Congress

    More Than Just Drain Pipes, Pulmonary Lymphatics Play a Pivotal Role in the Development of Bronchiolitis Obliterans Syndrome

    L. Wang1, R. Han2, H. Outtz Reed3, W. W. Hancock2

    1Childrens Hospital of Phila, Philadelphia, PA, 2Children's Hospital of Philadelphia, Philadelphia, PA, 3Weill Cornell, New York, NY

    *Purpose: Chronic allograft dysfunction (CLAD) remains a major determinant of the generally poor long-term outcome of lung transplantation compared to that of other solid organ…
  • 2022 American Transplant Congress

    Moral Distress Among Palliative Care and Transplant Clinicians in the Context of Transplant Care

    K. Ladin1, E. Park2, J. Perugini2, K. Aufort2, T. Porteny2

    1Tufts University, Medford, MA, 2REACH Lab, Tufts University, Medford, MA

    *Purpose: Despite benefits of palliative care referrals and early advance care planning for patients with end-stage organ disease and recipients experiencing graft failure, few patients…
  • 2022 American Transplant Congress

    First Report of Xenotransplantation from a Pig to Human Recipient

    J. Stern1, V. Tatapudi1, B. Lonze1, Z. Stewart1, M. Mangiola1, M. Wu1, S. Mehta1, E. Weldon1, R. Dieter1, N. Lawson1, A. Griesemer2, B. Parent1, G. Piper1, P. Sommer1, S. Cawthon1, B. Sullivan1, N. Ali1, R. A. Montgomery1

    1NYU Langone Transplant Institute, New York, NY, 2CUMC, New York, NY

    *Purpose: Xenotransplantation of genetically edited pig organs into human recipients can solve the global scarcity of organs for transplantation. Humans lack the α1,3-Gal glycan ubiquitously…
  • 2022 American Transplant Congress

    Early Clinical Experience With Nirmatrelvir/ritonavir For Treatment Of Covid-19 In Solid Organ Transplant Recipients

    D. Salerno1, D. Jennings2, N. Lange3, D. Kovac1, T. Shertel1, J. Chen4, J. Hedvat5, J. Scheffert1, R. S. Brown6, M. Pereira7

    1NewYork-Presbyterian Hospital, New York, NY, 2Long Island University, Brooklyn, NY, 3Pharmacy, NewYork-Presbyterian Hospital, New York, NY, 4Columbia University Irving Medical Center, Fort Lee, NJ, 5New York Presbyterian Hospital, Tenafly, NJ, 6Weill Cornell Medicine, New York, NY, 7New York Presbyterian Hospital, New York, NY

    *Purpose: Nirmatrelvir/ritonavir use has not yet been described in solid organ transplant recipients (SOTR) who become infected with COVID-19. The objective of our study was…
  • 2022 American Transplant Congress

    Novel Phenotype of Intragraft Endothelial Cells That Modulates CD4+ T Effector-Mediated Rejection

    J. Wedel, K. Liu, T. Seto, S. Kong, D. M. Briscoe

    Boston Children's Hospital, Boston, MA

    *Purpose: Previous studies have suggested that early adoptive transfer of Teff into Rag KO mice bearing cardiac transplants results in acute rejection. However, if transfer…
  • 2022 American Transplant Congress

    Evaluation of Diabetes-Free Life Expectancy Among Living Kidney Donors and Non-Donors with Obesity: A Longitudinal Cohort Study

    C. Killian1, R. Reed1, M. McLeod1, P. MacLennan1, V. Kumar1, S. Brooks1, A. Maynor1, L. Stanford1, G. Baker1, C. Schinstock2, J. Silkensen3, G. Roll4, D. Segev5, B. Orandi1, C. Lewis1, J. Locke1

    1University of Alabama at Birmingham, Birmingham, AL, 2Mayo Clinic, Rochester, MN, 3Hennepin County Medical Center, Minneapolis, MN, 4UCSF Medical Center, San Francisco, CA, 5Johns Hopkins University, Baltimore, MD

    *Purpose: The growing end stage kidney disease burden paired with substantial rates of obesity in the United States (US) has prompted increased approval of obese…
  • 2022 American Transplant Congress

    Race-Based Differences in Simultaneous Liver and Kidney Transplant Utilization and Outcomes

    L. Subbaraj1, J. Lai2, G. Cullaro2

    1Department of Internal Medicine, University of California San Francisco, San Francisco, CA, 2University of California San Francisco, San Francisco, CA

    *Purpose: Race-based variations in rates of kidney dysfunction exist. We aimed to understand the utilization and impact of simultaneous liver-kidney transplantation (SLKT) by race.*Methods: Patients…
  • 2022 American Transplant Congress

    Early Outcomes for Liver Transplant with Thoracoabdominal Normothermic Regional Perfusion for Donation After Circulatory Death: A Multi-Center Experience

    A. L. Brubaker1, A. Lee1, B. Jackson1, J. Berumen1, J. R. Parekh1, K. L. Mekeel1, A. R. Gupta2, J. M. Gardner2, T. Chaly3, A. K. Mathur4, C. Jadlowiec4, K. Reddy4, R. Nunez4, J. Bellingham5, E. Thomas6, J. R. Wellen7, M. Kearns1, V. Pretorius1, G. T. Schnickel1

    1UC San Diego, San Diego, CA, 2UC San Francisco, San Francisco, CA, 3Arizona Transplant Associates, Phoenix, AZ, 4Mayo Clinic Arizona, Phoenix, AZ, 5California Pacific Medical Center, Orinda, CA, 6University of Texas, San Antonio, TX, 7Washington University, Saint Louis, MO

    *Purpose: We evaluated early outcomes of liver transplant after thoracoabdominal normothermic regional perfusion (TA-NRP) for controlled donation after circulatory death (cDCD) donors.*Methods: We identified liver…
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