Abstracts Archive - Page 60 of 1683 - ATC Abstracts

2022 American Transplant Congress
Transplant Combined with Neoadjuvant Therapy Improves Survival for Patients with Liver-Limited, Locally Advanced Intrahepatic Cholangiocarcinoma: A SEER Database Analysis
G. G. Panayotova¹, M. Javle², S. Pentakota¹, F. Paterno¹, A. Amin¹, L. Brown¹, S. Simonishvili¹, Y. Qin¹, T. Ayorinde¹, G. Prakash¹, C. Conrad³, J. V. Guarrera¹, K. E. Lunsford¹
¹Rutgers New Jersey Medical School, Newark, NJ, ²University of Texas, MD Anderson Cancer Center, Houston, TX, ³St. Elizabeth's Medical Center, Boston, MA
*Purpose: Preliminary single-center data suggest multimodal therapy may improve outcomes for patients with intrahepatic cholangiocarcinoma (iCCA) undergoing liver transplant (LT), particularly in the setting of…
2022 American Transplant Congress
Longevity Matching for Living Donor Renal Transplantation
S. Karhadkar¹, J. Dawes¹, K. Wirshup¹, J. Kolansky¹, A. Gregor¹, A. Diamond², A. DiCarlo¹
¹Temple University Hospital, Philadelphia, PA, ²-, Garnet Valley, PA
*Purpose: Living donor kidney transplantation (LDKT) continues to become a more prevalent treatment method for ESRD and is known to increase both organ availability and…
2022 American Transplant Congress
Kidney Transplantation in Patients Postradical Prostatectomy
S. Karhadkar, K. Wirshup, J. Kolansky, A. Gregor, J. Dawes, A. DiCarlo
Temple University Hospital, Philadelphia, PA
*Purpose: The population of the United States is aging. By the year 2050 those over 65 years of age are projected to make up 20.2%…
2022 American Transplant Congress
Prevalence and Clinical Significance of Pancreatic Cystic Lesions in Immunosuppressed Patients with Solid Organ Transplantation
Y. Yu, H. Jo, Y. Choi, J. Lee, D. Kim
HBP surgery and liver transplantation, Korea University College of Medicine and School of Medicine, Seoul, Korea, Republic of
*Purpose: Solid organ transplant recipients have an increased risk of cancer due to immunosuppressive therapy. Pancreatic cystic lesions (PCLs) are increasingly being detected, some with…
2022 American Transplant Congress
Outcomes of Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists in Diabetic Kidney Transplant Recipients
T. S. Mahmoud¹, J. Yagan¹, A. Hasan², O. Gheith¹, M. Mostafa¹, S. Rida¹, N. El-Serwy¹, M. Shaker¹, M. Khalid¹, P. Nair¹, T. Alotaibi¹
¹Nephrology, Organ Transplant Center, Kuwait, Kuwait, ²Immunometabolism, Dasman Diabetes Center, Kuwait, Kuwait
*Purpose: The impact of the new glucose lowering therapies, sodium-glucose cotransporter 2 inhibitors (SGLT2i) and Glucagon-like peptide-1 receptor agonists (GLP-1RA), on managing patients with type…
2022 American Transplant Congress
Phase I/ii Car-Treg Cell Therapy Clinical Trial To Induce Long-term Tolerance In Liver Transplant Patients
A. Sanchez-Fueyo¹, A. Taylor¹, D. Collin², C. Nathalie², S. Chris², M. Martinez-Llordella², N. Belmonte², I. McGill², D. Hartl²
¹King's College London, London, United Kingdom, ²Quell Therapeutics Ltd, London, United Kingdom
*Purpose: Life-long pharmacological immunosuppression (IS) is considered essential to prevent rejection following liver transplantation (LT), but is associated with significant side effects such as infections,…
2022 American Transplant Congress
Prolonged Xeno-Kidney Graft Survival in Highly Allo-Sensitized Nonhuman Primate Using Triple-Knockout Donor Pigs with 7 Human Transgenes
M. Manook¹, D. Olaso¹, I. Anwar¹, J. Yoon¹, M. Song¹, A. B. Farris², K. Stiede³, K. Hall³, M. Youd³, S. Knechtle¹, J. Kwun¹
¹Surgery, Duke Transplant Center, Durham, NC, ²Pathology, Emory University, Atlanta, GA, ³eGenesis Inc, Cambridge, MA
*Purpose: We have previously shown using porcine kidneys from genetically modified knockout alpha 1,3-galactosyltransferase (GGTA1KO) and human decay accelerating factor transgenic (CD55Tg) pigs that compared…
2022 American Transplant Congress
Mortality in Solid Organ Transplant Recipients with a Pretransplant Cancer Diagnosis
A. Hart¹, R. Pfeiffer², B. Morawski³, C. Lynch⁴, Y. Zeng⁵, K. Pawlish⁶, K. Yu⁷, D. Hurley⁸, E. Engels⁷
¹Hennepin Healthcare, University of Minnesota, Minneapolis, MN, ²Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, ³Cancer Registry of Idaho, Boise, ID, ⁴Epidemiology, University of Iowa, Iowa City, IA, ⁵North Dakota Statewide Cancer Registry, Grand Forks, ND, ⁶New Jersey State Cancer Registry, Trenton, NJ, ⁷Infections and Immunoepidemiology Branch, National Cancer Institute, Bethesda, MD, ⁸University of South Carolina, Columbia, SC
*Purpose: Transplant-associated immunosuppression may cause cancer recurrence in patients with a pretransplant cancer, but little is known about outcomes among these recipients.*Methods: We used data…
2022 American Transplant Congress
The Other Reasons for Waitlist Removal
C. Martinez, J. Foutz, A. Placona, L. Cartwright
United Network for Organ Sharing, Richmond, VA
*Purpose: When a transplant program removes a candidate from the waitlist, they must either select a pre-defined removal code or type a response into the…
2022 American Transplant Congress
Fibroblastic Reticular Cell Subset Transcriptional Reprogramming Differs in Response to Immunity versus Tolerance
L. Li¹, Y. Song¹, M. Shirkey¹, A. Kensiski¹, W. Piao¹, V. Saxena¹, S. Gavzy¹, B. Ma¹, R. Abdi², J. Bromberg¹
¹UMB, Baltimore, MD, ²Harvard University, Boston, MD
*Purpose: Lymph node (LN) fibroblastic reticular cells (FRCs) are central contributors to the LN niche. We hypothesized that FRC subsets reactive to immunity versus tolerance…