2022 American Transplant Congress
Sodium-Glucose Cotransporter 2 Inhibitors to Treat Diabetes Mellitus After Kidney Transplant
*Purpose: This study describes experience prescribing sodium-glucose cotransport 2 inhibitors (SGLT2i) after kidney transplant to evaluate safety and effectiveness.*Methods: This is a retrospective, institutional review…2022 American Transplant Congress
Decellularized Human Pancreatic Extracellular Matrix-Based Physiomimetic Microenvironment for Human Islet Culture
*Purpose: Maintenance of human islet viability and function ex vivo can be a significant bottleneck for both regenerative medicine as well as tissue engineering applications.…2022 American Transplant Congress
Modification of Gut Microbiota Accelerates Kidney Repair After Experimental Ischemia Reperfusion Injury
Johns Hopkins Medicine, Baltimore, MD
*Purpose: Kidney ischemia reperfusion injury (IRI) leads to changes in gut microbiome, and pre-IR microbiome changes can modify course of experimental tissue injury. There is…2022 American Transplant Congress
HLA-II Subclasses Behave Differently Between Themselves and Between Humans: Cues to Understand Alloreactivity
*Purpose: De novo anti-HLA-II DSAs (dnDSA) are associated with antibody-mediated rejection. However, some patients with anti-HLA-II DSAs will not develop rejection, suggesting that the development…2022 American Transplant Congress
Dual Deceased Donor Kidney Transplants: Maximizing Utilization of Suboptimal Kidneys
Renal Transplant, Charleston Area Medical Center, Charleston, WV
*Purpose: To demonstrate that dual transplant of marginal kidneys is an underutilized strategy to minimize discard rates and mitigate organ shortage.*Methods: We compared dual kidney…2022 American Transplant Congress
Superoxide in Cardiac Allografts from Donors After Circulatory Death
*Purpose: Quality of cardiac allografts from donors after circulatory death (DCD) is adversely impacted by warm ischemia and subsequent reperfusion during organ resuscitation. Post-transplant myocardial…2022 American Transplant Congress
Longitudinal Mortality Risks and Renal Functional Outcomes in Living Kidney Donors
*Purpose: Previous studies have suggested that living kidney donors do not have a higher risk of death or end-stage kidney disease (ESKD) than the general…2022 American Transplant Congress
Lucas Device Assisted Uncontrolled Dcd Kidney Transplantation – A Feasible but Underutilized Option in the United States
Renal Transplant, Charleston Area Medical Center, Charleston, WV
*Purpose: Uncontrolled DCD (uDCD) procurement involves either normo-thermic or hypothermic regional perfusion to reduce ischemic injury. We report a series of successful kidney transplant utilizing…2022 American Transplant Congress
Single Blind Randomized Controlled Trial Comparing BNT162b2 Vs JNJ-78436735 Vaccine As An Additional Dose After Two Doses Of BNT162b2 Vaccine In Solid Organ Transplant (SOT) Recipients
*Purpose: Even though a high efficacy and immunogenicity of COVID-19 vaccines have been reported in the general population, vaccine immunogenicity is suboptimal in SOT recipients…2022 American Transplant Congress
Normothermic Organ Preservation: The New Standard?
*Purpose: Normothermic perfusion (NMP) is a new technique that has been introduced into transplantation expanding capacity for organ utilization. NMP has been shown to be…
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