Abstracts Archive - Page 596 of 1683 - ATC Abstracts

2019 American Transplant Congress
Outcomes Analysis of U.S. Transplant Centers Performing High Volumes of Hard to Place Kidneys
Y. Qazi¹, D. Bahl², N. Mehta³, Z. Haddad⁴, M. Smogorzewski⁴
¹USC, Los Angeles, CA, ²UC Davis, Sacramento, CA, ³UC Berkeley, Berkeley, CA, ⁴Keck Medical Center At USC, Los Angeles, CA
*Purpose: Despite a growing number of patients awaiting a kidney transplant, discard rate remains significantly high. The UNOS SRTR data now provides information on all…
2019 American Transplant Congress
Impact of the Pediatric End-Stage Liver Disease Growth Failure Threshold on Waitlist Mortality in Children Awaiting Liver Transplant
S. M. Swenson, J. P. Roberts, S. Rhee, E. R. Perito
University of California, San Francisco, San Francisco, CA
*Purpose: To examine the impact on waitlist mortality of Pediatric End-Stage Liver Disease (PELD)’s incorporation of growth failure (GF) as a threshold variable—present or absent…
2019 American Transplant Congress
Supercooling Preservation Prolonged Mouse Cardiac Graft Cold Ischemia Time
W. Que¹, X. Hu¹, M. Fujino¹, Y. Yamada², L. Zhong³, X. Li¹
¹Division of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan, ²Technican Co., Ltd., Kanagawa, Japan, ³Department of Surgery, Shanghai General Hospital, shanghai Jiao Tong University School of Medicine, Shanghai, China
*Purpose: Supercooling preservation techniques store a donor organ below 0°C without freezing. This has great advantages in inhibiting metabolism and preserving the organ in comparison…
2019 American Transplant Congress
Mycophenolate Mofetil versus Azathioprine in Kidney Transplant Recipients on Steroid-Free Low-Dose Cyclosporine Immunosuppression: The ATHENA Trial
P. Cravedi¹, P. Ruggenenti², E. Gotti², A. Plati², S. Sandrini³, N. Bossini³, F. Citterio⁴, E. Minetti⁵, D. Montanaro⁶, R. Tardanico³, E. Sabadini², F. Gaspari⁷, A. Villa⁷, F. Peraro⁷, G. Remuzzi⁷
¹Mount Sinai, New York, NY, ²ASST Ospedale Papa Giovanni XXIII, Bergamo, Italy, ³ASST degli Spedali Civili, Brescia, Italy, ⁴Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy, ⁵ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, ⁶Presidio Ospedaliero Universitario Santa Maria della Misericordia, Udine, Italy, ⁷Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy
*Purpose: Registration trials using old sandimmune formulation of cyclosporine (CsA) led to the general idea that Mycophenolate Mofetil (MMF) prevents acute cellular rejection (ACR) more…
2019 American Transplant Congress
Platelets Stimulate Liver Regeneration in a 30% Partial Liver Transplantation Model in Rat
C. Liang, K. Takahashi, T. Oda, N. Ohkohchi
University of Tsukuba, Tsukuba, Japan
*Purpose: Thirty years after the first living donor liver transplantation (LDLT), this technique has been widely recognized as the golden standard in treatment of end-stage…
2019 American Transplant Congress
Blood Profiling Reflects a Significant Down-Regulation in Oxidative Phosphorylation Following Renal Transplantation with DCD and AKI Allografts
S. Walker¹, L. Cox², C. Langefeld², B. Freedman², A. Farney², J. Rogers², C. Jay², R. Stratta², G. Orlando²
¹Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, ²Wake Forest Baptist Medical Center, Winston Salem, NC
*Purpose: The human kidney transplant (KT) patient provides a unique and compelling in situ model system to study molecular events that underlie graft recovery following…
2019 American Transplant Congress
Utilization of Hepatitis C Donors is Safe and Cost Effective
J. Shaw, D. Reino, N. Kapila, K. Al Khalloufi, S. Ebaid, S. Rhazouani, X. Zervos, J. Vanatta, N. Agrawal
Cleveland Clinic, Weston, FL
*Purpose: The use of hepatitis C (hep C) positive donors has become increasingly attractive with the advent of improved curative pharmacologic treatments. As a result…
2019 American Transplant Congress
Vimentin Inhibition Improves Post-Transplant Survival in a Mouse Renal Transplant Model
R. Lopez-Soler¹, Z. Zhang², H. Chin³, J. Wang⁴, K. Ridge⁵
¹Albany Medical College, Albany, NY, ²Microsurgery Core, Comprehensive Transplant Center, Northwestern University, Feinberg School of Medicine, Chicago, IL, ³Molecular and Cellular Physiology, Albany Medical College, Albany, NY, ⁴Microsurgery Core, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Northwestern Univesity, Feinberg School of Medicine, Chicago, IL
*Purpose: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…
2019 American Transplant Congress
Towards Human Leukocyte Antigen Immunogenicity Assessment at the Individual Patient Level
H. Copley¹, H. McDowell², D. Pinelli², A. R. Tambur², V. Kosmoliaptsis¹
¹Department of Surgery, University of Cambridge, Cambridge, United Kingdom, ²Department of Surgery, Feinberg School of Medicine, Comprehensive Transplant Center, Northwestern University, Chicago, IL
*Purpose: Allorecognition of donor HLA and induction of humoral alloimmunity is a major cause of graft loss after solid-organ transplantation. Current approaches to study molecular…
2019 American Transplant Congress
Organ Procurement Organization Performance is Not Related to Educational Spending
J. P. Roberts¹, J. Bragg-Gresham², P. Held³
¹Univ of California-San Francisco, San Francisco, CA, ²Nephrology, University of Michigan, Ann Arbor, MI, ³Stanford University, Stanford, CA
*Purpose: We examined the educational spending by OPOs in relationship to OPO performance metrics.*Methods: Data sources: OPO Cost Reports (CMS 216-94 Form), SRTR OPO Specific…