ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Increased Regulatory T-cells in Tumor Microenvironment is Associated with Hepatocellular Carcinoma Differentiation in Patients Undergoing Liver Transplantation

    G. Orozco1, R. Gedaly2, L. Turcios2, F. Marti2

    1Surgery, University of Kentucky, Lexington, KY, 2UKHC, Lexington, KY

    *Purpose: Tumor-infiltrating lymphocytes are an essential component of the tumor microenvironment. The balance between cytotoxic effector T cells and immunosuppressive regulatory T cells is critical…
  • 2022 American Transplant Congress

    In Vitro Fertilization Use Among Female Kidney Transplant Recipients

    L. A. Coscia1, J. M. Konel2, M. Bowring3, S. Constantinescu4, M. J. Moritz5

    1Transplant Pregnancy Registry International, Philadelphia, PA, 2Wayne State University School of Medicine, Detroit, MI, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 5Surgery, Lehigh Valley Health Network, Allentown, PA

    *Purpose: Infertility is common among female kidney transplant recipients (KTRs). In vitro fertilization (IVF) is a potential option. The purpose of this study was to…
  • 2022 American Transplant Congress

    Cardiac Catheterization in ESKD Patients with High Cardiovascular Risk Prior to Kidney Transplantation

    L. Morena1, A. Al Jurdi2, M. S. Bittencourt3, A. C. Bucay2, N. Elias1, R. Palsson2, L. V. Riella1

    1Transplant Surgery, Massachusetts General Hospital - Harvard Medical School, Boston, MA, 2Transplant Nephrology, Massachusetts General Hospital - Harvard Medical School, Boston, MA, 3Cardiac Imaging, Cardiology, University of Pittsburgh, Pittsburgh, PA

    *Purpose: Cardiovascular disease is the leading cause of death after kidney transplantation (KT), with a high risk of myocardial infarction (MI) in the peri-transplantation period.…
  • 2022 American Transplant Congress

    Area Deprivation Index is Associated with Worse Patient Survival Following Adult Liver Transplantation

    J. Hendele1, J. Perkins2, J. Nichols3, A. Dick1

    1Division of Transplant Surgery, Department of Surgery, University of Washington, Seattle, WA, 2Clinical and Bio-Analytics Transplant Laboratory (CBATL), University of Washington, Division of Transplant Surgery, Department of Surgery, Seattle, WA, 3School of Medicine, University of Washington, Seattle, WA

    *Purpose: Area Deprivation Index (ADI) has been utilized as a granular measure of local socioeconomic status for nearly two decades. This study is the first…
  • 2022 American Transplant Congress

    Autencoder, a Novel Computational Tool to Score T Cell Clones Demonstrates Biopsy T Cell Clones Are Not Represented in the Peripheral Blood

    N. Borcherding, A. Leckie-Harre, H. Wu, B. D. Humphreys, A. F. Malone

    Washington University, St Louis, MO

    *Purpose: Antibody-mediated rejection (AMR) remains one of the major causes of allograft failure and our understanding of this disease process is poor. The generation and…
  • 2022 American Transplant Congress

    Evaluation of Donor Exclusion Criteria in Living Donor Liver Transplantation: A Single-Center Experience

    D. Daskalaki, M. E. Akoad, J. Kim, C. J. Simon, Y. Cheah

    Hepatobiliary Surgery and Liver Transplantation, Lahey Hospital and Medical Center, Burlington, MA

    *Purpose: Liver donation is fundamental in increasing the pool of available grafts. Careful evaluation of each donor ensures the best outcomes for the recipient and…
  • 2022 American Transplant Congress

    Disruption of B Cell Population is Associated with Increased Infections in Pediatric Transplant Recipients

    B. Geng, L. Loop, C. Anterasian, D. Mortazavi, J. Kitsen, C. Collins, K. Newton, E. Ingulli

    Pediatrics, UCSD Rady Children's, San Diego, CA

    *Purpose: Solid-organ transplant recipients are placed on long-term immunosuppression, preventing graft rejection but increasing the risk of infection. Pediatric transplant recipients are at increased risk…
  • 2022 American Transplant Congress

    Long-Term Outcomes for Living Kidney Donors with Early Guideline-Concordant Follow-Up Care

    A. Dhalla1, A. Lloyd2, K. L. Lentine3, A. X. Garg4, R. R. Quinn1, P. Ravani1, S. W. Klarenbach2, B. R. Hemmelgarn2, U. Ibelo1, N. N. Lam1

    1Department of Medicine, Division of Nephrology, University of Calgary, Calgary, AB, Canada, 2Department of Medicine, Division of Nephrology, University of Alberta, Edmonton, AB, Canada, 3Center for Abdominal Transplantation, Saint Louis University, St. Louis, MO, 4Department of Medicine, Division of Nephrology, Western University, London, ON, Canada

    *Purpose: Current guidelines recommend that living kidney donors receive annual lifelong follow-up to monitor kidney health. It is unclear whether early guideline-concordant care is associated…
  • 2022 American Transplant Congress

    Association of Native Kidney Disease with De Novo Cancer Development After Kidney Transplant

    Y. Caliskan1, D. Axelrod2, R. Li1, W. Cheungpasitporn3, M. Schnitzler1, M. McAdams DeMarco4, J. Ahn4, T. Alhamad5, H. Randall1, S. Bae4, D. Segev4, K. L. Lentine1

    1Saint Louis University, Saint Louis, MO, 2University of Iowa, Iowa City, IA, 3Mayo Clinic, Rochester, MN, 4John Hopkins University, Baltimore, MD, 5Washington University in Saint Louis, Saint Louis, MO

    *Purpose: Primary glomerulonephritis (GN) and congenital anomalies of the kidney and urinary tract (CAKUT) have been shown to be associated with cancer development in the…
  • 2022 American Transplant Congress

    Establishing a Framework for Long-Term Follow-Up: A Survey of Perspectives and Preferences of Living Kidney Donors

    S. K. Singh1, N. Caton2, O. Johnston2, C. S. Hanson3, A. Dominello3, K. Yetzer4, D. Chang2, A. Tong3, J. S. Gill2

    1Department of Medicine, University of Toronto, Toronto, ON, Canada, 2Department of Medicine, University of British Columbia, Vancouver, BC, Canada, 3Sydney School of Public Health, University of Sydney, Sydney, Australia, 4Canadian Blood Services, Ottawa, ON, Canada

    *Purpose: There is currently no established standard for long-term follow-up of living kidney donors in Canada. To inform a new national standard, we sought to…
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