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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Seroprevalence of HHV8 Among Donors and Recipients with HIV

    P. H. Nambiar1, T. Liang2, J. D. Motter3, W. Werbel3, S. Mehta4, V. Kirchner5, M. Rana6, S. Florman7, J. Odim8, W. Miley9, N. Labo9, D. Whitby9, A. Massie10, D. Segev3, A. Tobian3, C. Durand2

    1Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 2Medicine, Johns Hopkins University, Baltimore, MD, 3Johns Hopkins University, Baltimore, MD, 4New York University Langone Transplant Institute, New York, NY, 5University of Minnesota, Minneapolis, MN, 6Icahn School of Medicine at Mount Sinai, New York, NY, 7Mount Sinai Medical Center, New York, NY, 8National Institute of Health, Bethesda, MD, 9National Cancer Institute, Frederick, MD, 10Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: Kaposi sarcoma (KS) can develop post-transplant via recipient HHV8 reactivation or donor-acquired HHV8. In the general US population, HHV8 seroprevalence is low (1-5%), yet…
  • 2022 American Transplant Congress

    Humoral Response After a Third Dose of Sars-CoV-2 mRNA Vaccine in Transplant Recipients

    A. E. Woolley, N. Sharma, G. Zhou, A. Kim, E. Ryan, M. Joyce, H. Goldberg, M. Givertz, M. Mehra, E. Woodcome, V. Durney, S. Marshall, K. Townsend, A. Coppolino, S. Tullius, S. Malek, H. Mallidi, L. Baden, A. Chandraker

    Brigham & Women's Hospital, Boston, MA

    *Purpose: Prior studies demonstrated an increased immune response post-3rd COVID-19 vaccine dose when given 1-month post-2nd dose in solid organ transplant recipients (SOT). This study…
  • 2022 American Transplant Congress

    Barriers and Facilitators to Care for Patients with Failed Kidney Transplants

    A. Huml1, K. Berg2, A. Perzynski2, C. Sullivan2, A. Sehgal2

    1Department of Kidney Medicine, Cleveland Clinic, Cleveland, OH, 2Population Health Research Institute, The MetroHealth System, Cleveland, OH

    *Purpose: To understand the barriers and facilitators to care for patients with failed kidney transplants from the perspective of providers.*Methods: Qualitative study employed focus groups…
  • 2022 American Transplant Congress

    Intermediate Term Outcomes of SGLT2 Inhibitors Amongst Diabetic Kidney Transplant Recipients

    C. Song1, A. Brown2, R. Winstead1, S. Sterling1, I. Yakubu2, J. Christensen2, G. Gupta2

    1Pharmacy, VCUHS, Richmond, VA, 2VCUHS, Richmond, VA

    *Purpose: The use of Sodium Glucose Linked Transporter Inhibitors (SGLT-2i) among non-transplant diabetic patients with chronic kidney disease (CKD) has demonstrated reduced cardiovascular mortality, delayed…
  • 2022 American Transplant Congress

    Early Clinical Experience With Alvr109, A Partially Hla-matched Sars-cov-2 Specific T-cell Therapy, In Immunocompromised Patients With Covid-19

    G. Haidar1, J. Jacobs2, K. Hughes2, K. McCormick2, A. Naqvi2, M. Agha2, T. Bogdanovich2, B. Johnson2, J. Kozar2, E. Lendermon2, C. Marino2, A. Raptis2, F. Silveira2, W. Marshall3, M. Miller3, E. Atillasoy3, J. Mellors2

    1University of Pittsburgh, Pittsburgh, PA, 2UPitt, Pittsburgh, PA, 3Allovir, Waltham, MA

    *Purpose: Therapies for COVID-19 in immunocompromised (IC) patients (pts), including transplant (tx) pts, are limited. We describe our experience with ALVR109, an allogeneic, partially HLA-matched…
  • 2022 American Transplant Congress

    Combined CyTOF and Elispot Investigation of CMV Response Over the First Year Post Kidney Transplantation

    T. Jouve1, L. Donadeu Casassas2, S. Hartzell3, E. Crespo2, M. Meneghini2, A. Torija2, P. Cravedi4, O. Bestard2

    1Nephrology, Vall d’Hebron Institut de Recerca (VHIR), Grenoble, Spain, 2Nephrology, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain, 3Mount Sinai Hospital, New York, NY, 4Mount Sinai, New York, NY

    *Purpose: CMV remains a threat for kidney transplant recipients (KTR). Deciphering the impact of CMV on the immune system of KTR has helped improving CMV…
  • 2022 American Transplant Congress

    Early Experience with Varicella Vaccination in Pediatric Heart Transplant Recipients

    A. Dipchand, M. Seifert-Hansen

    The Hospital of Sick Children, Toronto, ON, Canada

    *Purpose: International consensus guidelines to vaccinate children after transplant with varicella (VZV) vaccine exclude heart recipients due to insufficient evidence for safety, seroconversion rate, and…
  • 2022 American Transplant Congress

    In Vitro Fertilization Use Among Female Kidney Transplant Recipients

    L. A. Coscia1, J. M. Konel2, M. Bowring3, S. Constantinescu4, M. J. Moritz5

    1Transplant Pregnancy Registry International, Philadelphia, PA, 2Wayne State University School of Medicine, Detroit, MI, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 5Surgery, Lehigh Valley Health Network, Allentown, PA

    *Purpose: Infertility is common among female kidney transplant recipients (KTRs). In vitro fertilization (IVF) is a potential option. The purpose of this study was to…
  • 2022 American Transplant Congress

    Autencoder, a Novel Computational Tool to Score T Cell Clones Demonstrates Biopsy T Cell Clones Are Not Represented in the Peripheral Blood

    N. Borcherding, A. Leckie-Harre, H. Wu, B. D. Humphreys, A. F. Malone

    Washington University, St Louis, MO

    *Purpose: Antibody-mediated rejection (AMR) remains one of the major causes of allograft failure and our understanding of this disease process is poor. The generation and…
  • 2022 American Transplant Congress

    Comparing Disparities in Access to First and Re-Kidney Transplantation Among Hispanic and Black Adults in the United States

    S. Sandal1, J. Ahn2, V. Thompson3, T. Purnell4, M. Cantarovich5, D. Segev3, M. McAdams DeMarco3

    1McGill University, Montreal, QC, Canada, 2SOM, Johns Hopkins University, Baltimore, MD, 3Johns Hopkins University, Baltimore, MD, 4Johns Hopkins School of Medicine, Baltimore, MD, 5McGill University Health Ctr, Montreal, QC, Canada

    *Purpose: There are significant racial/ethnic disparities in access to solid organ transplantation; lack of education and familiarity with the transplant process are postulated contributors. Among…
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