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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Outcomes After Kidney Transplantation in Post Bariatric Surgery Patients: Systematic Review 

    N. Pencovici1, J. Long1, M. Stegall2, A. Kukla1, T. Diwan1

    1Mayo Clinic Rochester, Rochester, MN, 2Mayo Clinic, Rochester, MN

    *Purpose: Morbid obesity is a barrier to kidney transplantation (KT) due to increased perioperative risks and worse outcomes. Bariatric surgery (BS) is increasingly performed in…
  • 2022 American Transplant Congress

    Efficacy and Safety of Angiotensin II Compared to Catecholamine Vasopressors as a First-Line Vasopressor for Perioperative Hypotension in Kidney Transplant Recipients

    G. Urias1, J. Benken1, A. Lichvar2, D. Pierce1, L. Andrews1, K. Dalton3, A. Datta1, H. Nishioka1, E. Benedetti1, S. Benken1

    1University of Illinois at Chicago, Chicago, IL, 2University of California San Diego Health, San Diego, CA, 3St. David's Healthcare, Austin, TX

    *Purpose: Perioperative use of catecholamine vasopressors (CV) in kidney transplantation (KT) have been associated with negative renal outcomes and the development of arrhythmias. A more…
  • 2022 American Transplant Congress

    Post-Kidney Transplant Valacyclovir versus Valganciclovir for CMV Prophylaxis: A Randomized Controlled Trial

    P. S. Verghese1, A. Matas2, S. Chinnakotla2, M. Evans3, H. Balfour Jr4

    1Univ of Minnesota Pediatric Nephrology, Minneapolis, MN, 2Surgery, University of Minnesota Medical School, Minneapolis, MN, 3Biostatistics, University of Minnesota, Minneapolis, MN, 4Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN

    *Purpose: Valganciclovir (valG) is an effective CMV prophylactic agent post-kidney transplant (KTx) with significant side effects. Valacyclovir (valA) may be effective for CMV prophylaxis with…
  • 2022 American Transplant Congress

    Six-Month Outcomes Among Lung Transplant Patients with COVID-19

    L. D. Mahan, J. Rose, M. Mohanka, A. Banga

    UT Southwestern Medical Center, Dallas, TX

    *Purpose: There is limited data on the outcomes beyond the acute illness among lung transplant (LT) patients with Coronavirus disease 2019 (COVID-19). The current study…
  • 2022 American Transplant Congress

    Physiological Age by Artificial Intelligence-Enhanced Electrograms as a Novel Biomarker of Mortality in Kidney Transplant Candidates

    E. Lorenz, I. Zaniletti, B. Johnson, T. Petterson, W. Kremers, C. Schinstock, H. Amer, A. Cheville, N. LeBrasseur, A. Baez-Suarez, Z. Attia, F. Lopez-Jimenez, P. Friedman, C. Kennedy, A. Rule

    Mayo Clinic, Rochester, MN

    *Purpose: Assessing mortality risk prior to kidney transplantation is challenging. Age-Gap, which is the difference between physiological age determined by artificial intelligence-enhanced electrocardiograms (ECG) and…
  • 2022 American Transplant Congress

    EBV+ PTLD Tumor MicroRNAs Detected in Circulating Extracellular Vesicles Are Decreased in Pediatric Transplant Recipients with EBV+ PTLD

    A. Sen1, J. Enriquez1, M. Rao1, M. Glass1, Y. Balachandran1, S. Syed1, C. Twist1, K. Weinberg1, S. D. Boyd1, D. Bernstein1, A. Trickey1, D. Gratzinger1, B. Tan1, M. G. Lapasaran1, M. A. Robien2, M. Brown3, B. Armstrong4, M. Sever4, D. Desai5, G. Mazariegos6, C. Chin7, T. Fishbein8, R. S. Venick9, A. Tekin10, H. Zimmermann11, R. U. Trappe12, C. O. Esquivel1, O. M. Martinez1, S. M. Krams1

    1Stanford U, Palo Alto, CA, 2NIH, Bethesda, MD, 3NIAID, Bethesda, MD, 4Rho, Durham, NC, 5UT Southwestern, Dallas, TX, 6Pittsburgh U, Pittsburgh, PA, 7CCHMC, Cincinnati, OH, 8Georgetown U, Washington, DC, 9UCLA, LA, CA, 10Miami U, Miami, FL, 11DIAKO Ev. Diakonie-Krankenhaus, Bremen, Germany, 12Charité - Universitätsmedizin, Berlin, Germany

    *Purpose: Post-transplant lymphoproliferative disorder (PTLD) is a serious complication of solid organ transplantation. Predisposing factors for PTLD include primary Epstein-Barr virus (EBV) infection in children,…
  • 2022 American Transplant Congress

    Prevalence and Characteristics of Covid-19-Associated Pulmonary Diagnoses in Lung Transplant Patients in the United States

    T. G. Mupfudze1, A. R. Wilk1, R. R. Goff1, M. Valapour2, J. Miller3, M. Budev2, E. D. Lease4

    1Research Department, United Network for Organ Sharing, Richmond, VA, 2Respiratory Institute, Cleveland Clinic, Cleveland, OH, 3Scientific Registry of Transplant Recipients, Minneapolis, MN, 4Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, WA

    *Purpose: Lung transplant may be a viable treatment option for select patients with non-recoverable COVID-19-associated acute respiratory distress syndrome (ARDS) and COVID-19-associated pulmonary fibrosis. This…
  • 2022 American Transplant Congress

    The Renin Angiotensin System (RAS) After Pig-to-Baboon Kidney Transplantation

    C. Hansen-Estruch1, M. H. Bikhet1, M. Javed1, D. Ayares2, A. Katsurada3, R. Satou3, W. Shao3, D. K. Cooper1, L. G. Navar3, E. Judd4

    1Surgery, University of Alabama at Birmingham, Birmingham, AL, 2Revivicor, Blacksburg, VA, 3Department of Physiology and Hypertension and Renal Center, Tulane University, New Orleans, LA, 4Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Relatively long-term survival after life-supporting pig-to-baboon kidney transplantation has been achieved. However, there are documented episodes of hypovolemia during the post-transplant period from an…
  • 2022 American Transplant Congress

    Fibroblastic Reticular Cell Subset Transcriptional Reprogramming Differs in Response to Immunity versus Tolerance

    L. Li1, Y. Song1, M. Shirkey1, A. Kensiski1, W. Piao1, V. Saxena1, S. Gavzy1, B. Ma1, R. Abdi2, J. Bromberg1

    1UMB, Baltimore, MD, 2Harvard University, Boston, MD

    *Purpose: Lymph node (LN) fibroblastic reticular cells (FRCs) are central contributors to the LN niche. We hypothesized that FRC subsets reactive to immunity versus tolerance…
  • 2022 American Transplant Congress

    The Post-operative Clinical Outcomes Of 59 Tanrp Cases In An International Cohort

    J. Louca1, N. Patel1, S. Messer2, J. Chindu2, S. Large2

    1Cambridge University, Cambridge, United Kingdom, 2Royal Papworth Hospital, Cambridge, United Kingdom

    *Purpose: Heart transplantation is an immensely effective service and is currently the only definitive treatment for heart failure. However, transplantation is limited by donor availability.…
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