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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Reassessment of Previous Kidney Discards from a Single Large Organ Procurement Organization

    S. Bunnapradist1, T. Seto2, A. Cohen2, T. Rosenthal1, G. Danovitch1

    1David Geffen School of Medicine, Los Angeles, CA, 2One Legacy, Los Angeles, CA

    *Purpose: After deceased donor kidneys are recovered, they are offered according to UNOS policy and are discarded if no centers in the country would use…
  • 2022 American Transplant Congress

    Understanding the Response of Human Lung Microvascular Endothelial Cells During Lung Transplantation via an In Vitro Model of Ischemia Reperfusion Injury

    L. Chacon Alberty1, M. King1, G. Loor2, E. Curty1, C. Hochman-Mendez1

    1Regenerative Medicine Research, Texas Heart Institute, Houston, TX, 2Baylor College of Medicine - Lung Transplant, Houston

    *Purpose: Lung Transplantation (LTx) is a therapeutic option for patients with end-stage lung disease. One of the major complications is primary graft dysfunction largely attributed…
  • 2022 American Transplant Congress

    The Impact of Food Insecurity on Pediatric Kidney Transplant Outcomes

    A. Moin, J. Krissberg, D. Matossian, P. Verghese

    Pediatric Nephrology, Lurie Children's Hospital, Chicago, IL

    *Purpose: We previously demonstrated a prevalence of food insecurity (FI) of 26.7% at our institution, in a pilot study of 45 pediatric kidney transplant (pedsKTx)…
  • 2022 American Transplant Congress

    Case Times For Brain Dead Donors: Longer Is Not Better, No Impact Of Longer Case Time On Organ Yield Or OPO Performance Tier

    M. J. Moritz1, R. Hasz1, H. Nathan1, E. Hunt2, S. Noreen3, A. Toll4

    1Gift of Life Donor Program, Philadelphia, PA, 2Surgery, Lehigh Valley Health Network, Allentown, PA, 3United Network for Organ Sharing, Richmond, VA, 4Research, United Network for Organ Sharing, Silverdale, WA

    *Purpose: Having observed the steady increase in case times, we wished to examine if this has impacted organ yield*Methods: We conducted a retrospective cohort study…
  • 2022 American Transplant Congress

    Early versus Late Ureteral Stent Removal in Pediatric Kidney Transplant Recipients

    A. McGrath1, L. Maestretti1, S. Samreth1, K. Sheth2, P. Grimm2, A. Chaudhuri2, A. Gallo2

    1Stanford Children's, Palo Alto, CA, 2Stanford University, Palo Alto, CA

    *Purpose: Routine placement of ureteral stent in pediatric kidney transplantation prevents complications by reducing vesicoureteral junction kinking, and promoting drainage from the transplant kidney to…
  • 2022 American Transplant Congress

    Impact of Total Parenteral Nutrition on Donor Kidneys During Oxygenated Preservation at 22ºC Ex Vivo

    P. Luke1, A. Jackson2, A. Ruthirakanthan2, S. Juriasingani2, M. Levine1, L. Jiang2, R. Patel2, M. Richard-Mohamed1, S. Forrest1, A. Sener1, R. N. Bhattacharjee1

    1London Health Sciences Centre, London, ON, Canada, 2Western University, London, ON, Canada

    *Purpose: Recent studies have shown that ex vivo preservation at 37 º C can reduce kidney injury compared to current clinical practice. However, to mitigate…
  • 2022 American Transplant Congress

    Estrogen Receptor Beta Deletion is Protective in Renal Ischemia Reperfusion Injury but Pharmacologic Inhibition of Estrogen Receptor Beta is Not

    C. OBrien1, P. Hernandez2, S. Concors2, Z. Wang1, G. Ge1, W. Hancock3, M. Levine2

    1Surgery, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Childrens Hospital of Philadelphia, Philadelphia, PA

    *Purpose: Renal Ischemia Reperfusion Injury (IRI) contributes substantially to delayed graft function (DGF) in kidney transplantation. Prior work by our group has shown lower rates…
  • 2022 American Transplant Congress

    Decellularized Human Pancreatic Extracellular Matrix-Based Physiomimetic Microenvironment for Human Islet Culture

    A. Asthana1, D. Chaimov1, R. Tamburrini2, S. J. Walker3, G. Orlando1

    1Wake Forest Baptist Medical Center, Winston-Salem, NC, 2University of Wisconsin Hospital and Clinics, Madison, WI, 3Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC

    *Purpose: Maintenance of human islet viability and function ex vivo can be a significant bottleneck for both regenerative medicine as well as tissue engineering applications.…
  • 2022 American Transplant Congress

    Superoxide in Cardiac Allografts from Donors After Circulatory Death

    M. Urban1, T. Bruett2, K. F. Duncan1, N. W. Markin3, M. M. Chacon3, M. C. Zimmerman4

    1Department of Surgery. Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE, 2College of Medicine. Department of Cellular and Integtrative Physiology., University of Nebraska Medical Center, Omaha, NE, 3Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, 4Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE

    *Purpose: Quality of cardiac allografts from donors after circulatory death (DCD) is adversely impacted by warm ischemia and subsequent reperfusion during organ resuscitation. Post-transplant myocardial…
  • 2022 American Transplant Congress

    Invasive Fungal Infections Associated with COVID-19 Infections in Solid Organ Transplant Recipients

    R. Alameer, M. Nguyen, P. Samanta

    Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Invasive fungal infection (IFI) complicating Coronavirus disease of 2019 (COVID-19) has been increasingly recognized. IFI is a common opportunistic infection in solid organ transplant…
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