ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    The Effect of Pulsatile Pump Perfusion on Hepatitis C Viremia and Transmission in Kidney Transplantation: A Prospective Pilot Study

    R. Forbes1, B. Concepcion1, D. Clapper2, B. Dubray1, A. Miller2, D. Shaffer1, K. Johnson2

    1Vanderbilt University Medical Center, Nashville, TN, 2Tennessee Donor Services, Nashville, TN

    *Purpose: With increasing utilization of hepatitis C (HCV) viremic donor organs for aviremic recipients, there may be a role for kidney pulsatile pump perfusion to…
  • 2020 American Transplant Congress

    The Case Against Race: Proportion of Minorities Does Not Explain Low DSA Donation Performance

    R. Lynch, K. Ross, D. Goldberg

    Emory University Hospital, Atlanta, GA

    *Purpose: Chronic organ shortages result in unnecessary waitlist deaths, making improvements in donation an urgent problem in transplantation. Historically, barriers to donation have been noted…
  • 2020 American Transplant Congress

    Less is More: A Single Brain Death Exam Improves Organ Donation Outcomes

    A. J. Matar1, H. Wichmann2, L. Kenney2, A. Subramanian3, J. Ratcliff4, V. Patel4, B. M. Tracy2, R. B. Gelbard2

    1Surgery and Transplantation, Emory University, Atlanta, GA, 2Surgery, Emory University, Atlanta, GA, 3Surgery, Lawnwood Regional Medical Center, Fort Pierce, FL, 4Neurosurgery, Emory University, Atlanta, GA

    *Purpose: The diagnosis of brain death in adults has historically required two brain death examinations (TBD) before considering organ donation. Despite American Academy of Neurology…
  • 2020 American Transplant Congress

    Do the Characteristics of Donor Specific Antibody Truly Predict Severity of Cardiac Allograft Vasculopathy Late after Transplantation?

    K. Nishihara, J. Patel, M. Kittleson, D. Chang, E. Kransdorf, D. Geft, A. Shen, L. Czer, F. Esmailian, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: The development of donor specific antibody (DSA) has been correlated to the development of cardiac allograft vasculopathy (CAV) after heart transplantation. However, it has…
  • 2020 American Transplant Congress

    Multiplicity of Non-HLA Targets for Antibodies Developed in Association with Ventricular Assist Device Implantation

    M. Askar, D. Bhakta, H. Zafar, A. Alam, L. Pittmon, S. Kang, L. Klingman, J. Felius, S. M. Joseph, D. Wencker, D. M. Meyer, S. A. Hall

    Baylor University Medical Center and Baylor Scott & White Research Institute, Dallas, TX

    *Purpose: Multiple non-HLA antibodies have been implicated in poor outcomes after heart transplantation. Development of HLA and Non-HLA antibodies have been reported in association with…
  • 2020 American Transplant Congress

    Possible Mechanism of Sensitization against Angiotensin Type II Receptor after LVAD Implantation

    P. Kimball1, V. Chau2, F. McDougan1, M. Flattery2, K. Shah2

    1Surgery, VCUHS, Richmond, VA, 2Cardiology, VCUHS, Richmond, VA

    *Purpose: Detection of antibody (Ab) against angiotensin-II receptor (AT1R) following VAD implantation portends poorer outcomes for heart transplantation (HT). However, the cause of this sensitization…
  • 2020 American Transplant Congress

    C-Reactive Protein 1-Year Post-Transplant is Associated with Future Development of Coronary Artery Vasculopathy and Rejection in a Pediatric Heart Transplant Cohort

    H. J. Tadros, A. H. Bashir, F. J. Fricker, B. A. Pietra, D. Gupta

    Congenital Heart Center/Pediatrics, University of Florida, Gainesville, FL

    *Purpose: Coronary artery vasculopathy (CAV) is one of the leading causes of mortality beyond 3y post-transplant (OHT). Multiple risk factors are associated with development of…
  • 2020 American Transplant Congress

    The Liver Protects All? Donor Specific Antibody Formation in Heart-Liver Transplant Recipients

    A. W. Rogers1, T. N. Eagar2, C. Pham1, J. Krisl1, B. J. Pierce1, M. Moaddab1, R. Ghobrial3, B. Trachtenberg4, A. Bhimaraj4, A. O. Gaber3

    1Department of Pharmacy, Houston Methodist Hospital, Houston, TX, 2Department of Pathology, Houston Methodist Hospital, Houston, TX, 3Department of Surgery, Houston Methodist Hospital, Houston, TX, 4Houston Methodist Hospital, Houston, TX

    *Purpose: Donor specific antibodies (DSAs) are key in the development of antibody mediated rejection (AMR). Their role in decreased patient and graft survival has been…
  • 2020 American Transplant Congress

    Divergent Molecular Pathways Underlie the Evolution of Allograft Fibrosis in Two Mouse Models of Chronic Lung Allograft Dysfunction

    T. Watanabe, J. Allen, K. Boonstra, Z. Guan, K. Bei, S. Keshavjee, J. Yeung, T. Martinu, S. Juvet

    Latner Thoracic Surgery Research Laboratories, Toronto Lung Transplant Program / University Health Network, Toronto, ON, Canada

    *Purpose: Chronic lung allograft dysfunction (CLAD) after lung transplantation (LTx) is potentiated by activation of the innate immune system and occurs in two patterns: diffuse…
  • 2020 American Transplant Congress

    Ambient Air Pollution and Waitlist Mortality among Lung Transplant Candidates

    Y. Feng1, M. R. Jones2, N. Chu1, D. Segev1, M. McAdams-DeMarco1

    1Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD, 2Department Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD

    *Purpose: Previous studies suggested that air pollution is associate with higher risk of respiratory diseases and accelerated decline in lung function among general population. However,…
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