ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Incident Malignancies among Post Kidney-Transplant Patients by Type of Induction Immunosuppression and by Age

    L. Wang, J. Motter, S. Bae, D. Segev, M. McAdams DeMarco

    Johns Hopkins University, Baltimore, MD

    *Purpose: Adult kidney-transplant (KT) recipients have a differential risk of malignancies based on their induction immunosuppression (IS) therapy. However, older recipients are more likely to…
  • 2020 American Transplant Congress

    The FcγRIIIa-158 VV Genotype Increased the Risk of Post-Transplant Lymphoproliferative Disorder in T-Cell Depleted Kidney Transplant Recipients

    P. Gatault1, L. Lajoie1, J. Stojanova2, P. Marquet2, G. Thibault1

    1CHU Tours, Tours, France, 2CHU Limoges, Limoges, France

    *Purpose: Post-transplantation lymphoproliferative disorder (PTLD) is a severe complication in organ transplant recipients. The use of T lymphocyte-depleting antibodies (TLDAb), especially rabbit TLDAb contributes to…
  • 2020 American Transplant Congress

    Anti-Thymocyte Globulin versus Interleukin-2 Receptor Antagonist and Deceased-Donor Kidney Transplant Outcomes among Older Recipients

    J. Ahn1, S. Bae1, K. Lentine2, M. Schnitzler2, G. Hess3, D. Segev1, M. McAdams-DeMarco1

    1Johns Hopkins University, Baltimore, MD, 2Saint Louis University, St. Louis, MO, 3Drexel University, Philadelphia, PA

    *Purpose: Kidney transplantation (KT) has been growing treatment option for older end-stage renal disease patients. Although lymphocyte-depleting agents are considered to be superior than interleukin-2…
  • 2020 American Transplant Congress

    Survival Benefit of Accepting Kidneys from Older Donation after Cardiac Death Donors

    S. Yu, J. Long, Y. Yu, M. Bowring, J. Motter, T. Ishaque, D. Segev, J. Garonzik-Wang, A. Massie

    Johns Hopkins, Baltimore, MD

    *Purpose: Kidneys from older donation after cardiac death (DCD) donors are less likely to be transplanted due to concerns about inferior post-transplant survival. But candidates…
  • 2020 American Transplant Congress

    Broader Distribution of Kidneys Not Projected to Systematically Favor “Low” Performing OPOs

    A. Wilk1, S. Gustafson2, D. Stewart1, N. Salkowski2, D. Zaun2, J. Snyder2

    1UNOS, Richmond, VA, 2Hennepin Healthcare Research Institute, Minneapolis, MN

    *Purpose: In August 2019, the OPTN Kidney (KI) Transplantation Committee put forth a proposal for public comment to replace DSA and region from KI allocation…
  • 2020 American Transplant Congress

    UNOS Hard to Place Kidneys: Are We Working Too Hard?

    S. Chaudhry, K. L. King, S. A. Husain, D. Cohen, L. Ratner, S. Mohan

    Columbia University, New York, NY

    *Purpose: Kidneys requiring more than 100 offers before acceptance are defined by UNOS as “hard to place," but many are suitable for transplantation. We sought…
  • 2020 American Transplant Congress

    A Single-Center Analysis of Using Allele-Level 11 HLA Loci Information on cPRA and Organ-Allocation Points in Kidney Transplant Candidates

    C. Maguire1, P. Muluhngwi1, E. Kransdorf2, L. Gragert3, A. R. Tambur1

    1Northwestern University, Chicago, IL, 2Cedars-Sinai Heart Institute, Beverly Hills, CA, 3Tulane University, New Orleans, LA

    *Purpose: Calculated panel reactive antibodies (cPRA) is used by the United Network for Organ Sharing (UNOS) to quantify degree of HLA sensitization and assign priority…
  • 2020 American Transplant Congress

    Intimal Arteritis in Association with Microvascular Inflammation Leads to Inferior Graft Survival Regardless DSA

    M. Novotny1, E. Honsova2, O. Viklicky1

    1Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 2Department of Clinical and Transplant Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: Intimal arteritis belongs between diagnostic criteria of both antibody-mediated rejection (AMR) and T cell-mediated vascular rejection (TCMRV). Patients with intimal arteritis must be assessed…
  • 2020 American Transplant Congress

    Long Term Graft Outcome after Subclinical Banff Borderline Changes Suspicious for Acute T Cell-Mediated Rejection

    A. Han, H. Ko, C. Chung, H. Kim, S. Min, J. Ha

    Seoul National University College of Medicine, Seoul, Korea, Republic of

    *Purpose: Long term data after Banff borderline changes suspicious for acute T cell-mediated rejection (BDR lesion) are scarce, and hence, there is little evidence to…
  • 2020 American Transplant Congress

    CD56DimCD16Bright NK Cells from Kidney Transplant Recipients with Antibody-Mediated Rejection Display Increased Proliferation, Self-Renewal, Pro-Inflammatory and Cytotoxic Profile

    E. A. Bailly1, K. Louis1, C. Macedo1, B. Ramaswami1, M. Lucas1, A. Zeevi1, C. Lefaucheur2, D. Metes1

    1Department of Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, 2INSERM UMR-S976. Endothelium, Inflammation & Alloreactivity, Université de Paris, France

    *Purpose: Contribution of NK cells to antibody-mediated rejection (ABMR) injuries have recently been highlighted through transcriptomic analysis and immunohistochemistry of kidney and heart allograft biopsies.…
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