Abstracts Archive - Page 537 of 1683 - ATC Abstracts

2020 American Transplant Congress
Effectiveness of Bezlotoxumab for Prevention of Recurrent Clostridioides Difficile Infection among Transplant Recipients
V. Bajrovic¹, T. Johnson², A. Howard², L. Allen³, G. Barber², K. Schwarz², M. Huang³, M. Abidi¹, E. Benamu³, P. Ramanan³, M. Miller⁴
¹Division of Infectious Diseases, University of Colorado, Denver, CO, ²Department of Pharmacy, University of Colorado, Aurora, CO, ³Division of Infectious Diseases, University of Colorado, Aurora, CO, ⁴Department of Pharmacy, University of Colorado, Denver, CO
*Purpose: Clostridioides difficile is an urgent health threat associated with significant morbidity and mortality. Recipients of solid organ (SOT) and hematopoietic-cell transplantations (HCT) are at…
2020 American Transplant Congress
Donor Intervention and Recipient Treatment with Recombinant Human C1 Inhibitor Prevents Delayed Graft Function in a Non-Human Primate Model of Kidney Transplantation
J. A. Reyes¹, C. Blanton¹, M. Eerhart¹, P. Chlebeck¹, M. Springer¹, Y. Ponstein², E. van Amersfoort², J. Torrealba³, Y. Yankol¹, A. D'Allessandro¹, L. Fernandez¹
¹Surgery, University of Wisconsin, Madison, WI, ²Pharming Technologies BV, Leiden, Netherlands, ³Pathology, UT Soutwestern, Dallas, TX
*Purpose: There is currently no FDA-approved treatment to prevent delayed graft function (DGF) in kidney transplantation. We have shown that donor or recipient treatment with…
2020 American Transplant Congress
A Stroke Volume-Based Fluid Resuscitation Protocol Decreases Vasopressor Support and Increases Organ Yield in Brain-Dead Donors
G. F. Marklin
Mid-America Transplant, St Louis, MO
*Purpose: Brain-dead donors are frequently hypovolemic and hypotensive requiring vasopressor support. The goal of fluid resuscitation is to increase perfusion and oxygen delivery and avoid…
2020 American Transplant Congress
The Effect of Pulsatile Pump Perfusion on Hepatitis C Viremia and Transmission in Kidney Transplantation: A Prospective Pilot Study
R. Forbes¹, B. Concepcion¹, D. Clapper², B. Dubray¹, A. Miller², D. Shaffer¹, K. Johnson²
¹Vanderbilt University Medical Center, Nashville, TN, ²Tennessee Donor Services, Nashville, TN
*Purpose: With increasing utilization of hepatitis C (HCV) viremic donor organs for aviremic recipients, there may be a role for kidney pulsatile pump perfusion to…
2020 American Transplant Congress
Does the Type of Procurement and Preservation Influence the Results after Non-Heart-Beating Kidney Transplant from a Maastricht III Donor?
V. López, C. Casas, J. Alonso, M. Cabello, D. Hernández
Nephrology Services, Regional University Hospital, University of Malaga, IBIMA, REDinREN (RD16/0009/0006), Málaga, Spain
*Purpose: The use of extracorporeal membrane oxygenation (ECMO) systems for the preservation of organs from a controlled non-heart-beating donor has greatly increased over recent years.…
2020 American Transplant Congress
The Case Against Race: Proportion of Minorities Does Not Explain Low DSA Donation Performance
R. Lynch, K. Ross, D. Goldberg
Emory University Hospital, Atlanta, GA
*Purpose: Chronic organ shortages result in unnecessary waitlist deaths, making improvements in donation an urgent problem in transplantation. Historically, barriers to donation have been noted…
2020 American Transplant Congress
Less is More: A Single Brain Death Exam Improves Organ Donation Outcomes
A. J. Matar¹, H. Wichmann², L. Kenney², A. Subramanian³, J. Ratcliff⁴, V. Patel⁴, B. M. Tracy², R. B. Gelbard²
¹Surgery and Transplantation, Emory University, Atlanta, GA, ²Surgery, Emory University, Atlanta, GA, ³Surgery, Lawnwood Regional Medical Center, Fort Pierce, FL, ⁴Neurosurgery, Emory University, Atlanta, GA
*Purpose: The diagnosis of brain death in adults has historically required two brain death examinations (TBD) before considering organ donation. Despite American Academy of Neurology…
2020 American Transplant Congress
Multiplicity of Non-HLA Targets for Antibodies Developed in Association with Ventricular Assist Device Implantation
M. Askar, D. Bhakta, H. Zafar, A. Alam, L. Pittmon, S. Kang, L. Klingman, J. Felius, S. M. Joseph, D. Wencker, D. M. Meyer, S. A. Hall
Baylor University Medical Center and Baylor Scott & White Research Institute, Dallas, TX
*Purpose: Multiple non-HLA antibodies have been implicated in poor outcomes after heart transplantation. Development of HLA and Non-HLA antibodies have been reported in association with…
2020 American Transplant Congress
Computer-Assisted Cardiac Histologic Evaluation (CACHE) for Grading Cardiac Allograft Rejection
E. Peyster¹, S. ArabYarmohommadi², A. Janowczyk², M. Sekulic³, C. Cassol⁴, M. Feldman¹, K. Margulies¹, A. Madabhushi²
¹University of Pennsylvania, Philadelphia, PA, ²Case Western Reserve University, Cleveland, OH, ³University Hospitals Cleveland Medical Center, Cleveland, OH, ⁴Ohio State University, Columbus, OH
*Purpose: Cardiac allograft rejection (CAR) is a serious concern in heart transplantation, occurring in 30-40% of patients during the first year. Endomyocardial biopsy (EMB) with…
2020 American Transplant Congress
C-Reactive Protein 1-Year Post-Transplant is Associated with Future Development of Coronary Artery Vasculopathy and Rejection in a Pediatric Heart Transplant Cohort
H. J. Tadros, A. H. Bashir, F. J. Fricker, B. A. Pietra, D. Gupta
Congenital Heart Center/Pediatrics, University of Florida, Gainesville, FL
*Purpose: Coronary artery vasculopathy (CAV) is one of the leading causes of mortality beyond 3y post-transplant (OHT). Multiple risk factors are associated with development of…