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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Single Center Experience with Acute Kidney Injury Deceased Donor Kidneys from Marginal Donors

    B. K. Sharda, M. Garner, A. Farney, G. Orlando, C. Jay, J. Rogers, A. Daniel, A. Gutierrez, N. Sakhovskaya, R. Stratta

    Atrium Health Wake Forest Baptist Medical Center, Winston Salem, NC

    *Purpose: Many centers will selectively transplant kidneys from standard criteria donors (SCD) with terminal acute kidney injury (AKI). However, there is limited experience with transplanting…
  • 2022 American Transplant Congress

    Parathyroidectomy versus Cinacalcet in the Treatment of Tertiary Hyperparathyroidism After Kidney Transplantation

    C. Baek

    Asan Medical Center, Seoul, Korea, Republic of

    *Purpose: Hyperparathyroidism is prominent in patients with chronic kidney disease with reduced renal function and has been observed after kidney transplantation. There is a debate…
  • 2022 American Transplant Congress

    Inhibition of ITGB5 Protects Hepatocytes from Ischemia Reperfusion Injury

    M. Dogan1, S. Naik1, C. Watkins1, A. Bajwa1, V. Mas2, J. Eason3, C. Kuscu1, C. Kuscu1

    1Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, 2Surgery, University of Maryland, Baltimore, MD, 3University of Tennessee/Methodist Transplant Institute, Memphis, TN

    *Purpose: Liver transplantation is the best treatment option for patients with end-stage liver disease (ESLD). Despite the increasing interest to the machine reperfusion, cold preservation…
  • 2022 American Transplant Congress

    Deceased Donor Kidney Transplantation from Donors with Acute Kidney Injury: Realities and Costs

    S. Iskhagi1, R. Shahbazov1, A. Ball1, S. Loerzel1, E. Shaban2, B. Gallay2, R. Hod Dvorai3, J. Leggat2, M. Hanlon1, R. Saidi1

    1Department of Surgery, Division of Transplantation, SUNY Upstate Medical University, Syracuse, NY, 2Department of Medicine, Division of Nephrology, SUNY Upstate Medical University, Syracuse, NY, 3Department of Pathology and Laboratory Medicine, SUNY Upstate Medical University, Syracuse, NY

    *Purpose: The use of kidneys from deceased donors with acute kidney injury (AKI) is one of the options to expand donor pool. Several studied have…
  • 2022 American Transplant Congress

    CD38 Knockout Mice Demonstrate Decreased Neutrophil Infiltration Following Renal Ischemia Reperfusion Injury

    I. Woelfel1, A. Ruffing1, I. El-Ayachi1, K. Washburn2, S. Black1, A. Schenk1

    1Ohio State University, Columbus, OH, 2The Ohio State University, Columbus, OH

    *Purpose: Ischemia reperfusion injury (IRI) perpetuates inflammation and causes significant organ injury in solid organ transplantation. CD38 is a ectoenzyme widely expressed on lymphocytes with…
  • 2022 American Transplant Congress

    Survival Benefit of Early Kidney Transplantation in Infants and Toddlers

    S. J. Kizilbash1, M. Evans2, D. Vock2, B. Chavers3

    1University of MInnesota, Minneapolis, MN, 2University of Minnesota, Minneapolis, MN, 3Division of Nephrology, Minneapolis, MN

    *Purpose: The 1-year mortality in children with end-stage kidney disease (ESKD) has been the highest among infants and toddlers. The objective of this study was…
  • 2022 American Transplant Congress

    Single Center Retrospective Study Examining the Safety of the New Potassium- Binders for Post-Operative Hyperkalemia in Kidney Transplant Recipients

    S. Kapoor1, A. Campbell2, Y. Azzi1, L. E. Liriano-Ward3, T. Shertel4, W. Xiao5, D. U. Nnani6, S. Farghaly1, S. Yun7, E. Akalin1, M. Ajaimy1

    1Einstein-Montefiore Transplant Center, Bronx, NY, 2Montefiore Medical Center, Bronx, NY, 3Transplant, Montefiore Medical Center, Bronx, NY, 4-, -, AL, 5Albert Einstein College of Medicine, Folsom, CA, 6Pharmacy, Montefiore Medical Center, Bronx, NY, 7Montefiore Medical Center, New York, NY

    *Purpose: We aimed to evaluate the safety and efficacy of two potassium-binders (Patiromer and Sodium Zirconium Cyclosilicate (SZC) in early post-transplant hyperkalemia treatment of kidney…
  • 2022 American Transplant Congress

    Investigating RNA Interference-Mediated Inhibition of Liver Ischemia Reperfusion Injury During Liver Preservation

    J. E. Buchwald1, D. Echeverria2, J. Sousa2, N. McHugh2, A. Khvorova2, P. N. Martins3

    1RNA Therapeutics Institute, Department of Surgery, University of Massachusetts Chan Medical School, Worcester, MA, 2RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, 3Department of Surgery, University of Massachusetts Chan Medical School, Worcester, MA

    *Purpose: Liver transplantation cures acute end-stage and chronic liver diseases, yet current strategies of organ preservation including static cold storage (SCS) and machine perfusion (MP)…
  • 2022 American Transplant Congress

    HDAC6 Inhibition Mediated Protection from Hepatic Ischemia Reperfusion is Associated with Preserved Glutathione Levels

    C. OBrien1, P. Hernandez1, S. Concors2, Z. Wang1, G. Ge3, A. Kozikowski4, W. Hancock5, M. Levine2

    1Surgery, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Surgery, University of Pensylvania, Philadelphia, PA, 4College of Pharmacy, University of Illinois at Chicago, Chicago, IL, 5Childrens Hospital of Philadelphia, Philadelphia, PA

    *Purpose: Liver Ischemia reperfusion injury (IRI) and Acetaminophen (APAP) toxicity are important causes of acute liver failure in the United States, that lack effective therapy.…
  • 2022 American Transplant Congress

    Frequency of Cervical Cancer Screening in Solid Organ Transplant Recipients

    C. Papastamelos1, K. Dokus2, M. Laryea3

    1Internal Medicine, University of Rochester Medical Center, Rochester, NY, 2Transplant Division, University of Rochester Medical Center, Rochester, NY, 3Gastroenterology, University of Rochester Medical Center, Rochester, NY

    *Purpose: Human papillomavirus-related anogenital malignancies disproportionately affect solid organ transplant recipients (SOTR) compared to the general population. Proposed cervical Pap testing intervals for SOTR differ…
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