ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    A Third Dose of SARS-CoV-2 Vaccine Increases Neutralizing Antibodies Against Variants of Concern in Solid Organ Transplant Recipients

    A. H. Karaba1, X. Zhu1, T. Ling1, K. H. Wang1, A. G. Rittenhouse1, O. Akinde1, Y. Eby1, J. E. Ruff1, J. N. Blankson1, A. T. Abedon1, J. L. Alejo1, A. L. Cox1, J. R. Bailey1, E. A. Thompson1, S. L. Klein1, D. S. Warren1, J. M. Garonzik-Wang2, B. J. Boyarsky1, I. Sitaras1, A. Pekosz1, D. L. Segev1, A. A. Tobian1, W. A. Werbel1

    1Johns Hopkins University, Baltimore, MD, 2University of Wisconsin School of Medicine and Health, Madison, WI

    *Purpose: Vaccine-induced SARS-CoV-2 antibody responses are attenuated in solid organ transplant recipients (SOTRs) and breakthrough infections are more common. Additional SARS-CoV-2 vaccine doses increase anti-spike…
  • 2022 American Transplant Congress

    LGALS1 is Expressed in Glomerular Endothelial Cells and Induced Upon Stimulation with Anti-HLA Antibody

    A. Boshart1, S. Farkona1, S. Clotet-Freixas1, C. McEvoy1, J. Murphy1, S. Crome2, A. Konvalinka3

    1Toronto General Hospital Research Institute, Ajmera Transplant Centre, University Health Network, Toronto, ON, Canada, 2Immunology, Toronto General Hospital Research Institute, Ajmera Transplant Centre, University of Toronto, University Health Network, Toronto, ON, Canada, 3Nephrology, Toronto General Hospital Research Institute, Ajmera Transplant Centre, University Health Network, Toronto, ON, Canada

    *Purpose: Antibody-mediated rejection (AMR) accounts for >50% of premature kidney graft loss. AMR is caused by donor specific antibodies (DSA) against human leukocyte antigens (HLA)…
  • 2022 American Transplant Congress

    Early Outcomes Since Implementation of New Kidney Allocation System

    K. Shah, F. Siddiqui, P. N. Chotai, A. Logan, A. Schenk, K. Washburn, A. Limkemann

    Comprehensive Transplant Center, The Ohio State University Wexner Medical Center, Columbus, OH

    *Purpose: The new Kidney allocation system (nKAS) implemented for optimization of organ placement. Like other organ allocation systems, kidney has been redefined from donation service…
  • 2022 American Transplant Congress

    Concurrent Use of Two Methods Prevents Erroneous HLA Typing of Deceased Organ Donors – An Essential Strategy for Patient Safety and Accurate Virtual Crossmatching for Broader Sharing

    R. Rajalingam, T. dela Cruz, C. Dames, L. Pagaduan, Y. Cho, D. Kong

    Immunogenetics and Transplantation Laboratory (ITL), University of California San Francisco, San Francisco, CA

    *Purpose: Comprehensive and accurate typing for ever-increasing alleles of all eleven HLA genes within a short turnaround time is a crucial initial step for allocating…
  • 2022 American Transplant Congress

    Frequency of Cervical Cancer Screening in Solid Organ Transplant Recipients

    C. Papastamelos1, K. Dokus2, M. Laryea3

    1Internal Medicine, University of Rochester Medical Center, Rochester, NY, 2Transplant Division, University of Rochester Medical Center, Rochester, NY, 3Gastroenterology, University of Rochester Medical Center, Rochester, NY

    *Purpose: Human papillomavirus-related anogenital malignancies disproportionately affect solid organ transplant recipients (SOTR) compared to the general population. Proposed cervical Pap testing intervals for SOTR differ…
  • 2022 American Transplant Congress

    Kidney Transplantation from Covid-19 Deceased Donors

    M. M. Ibrahim, M. Merzkani, H. Murad, A. Pande, E. Dubberke, T. Alhamad

    Medicine/Nephrology, Washington University in St. Louis, St. Louis, MO

    *Purpose: Transplant volumes decreased significantly during the first months of global pandemic of COVID-19, followed by a shift in the standard of care of transplant…
  • 2022 American Transplant Congress

    Performance of Kidney Transplantation in a Resource-Poor Setting of Southeast Nigeria- A Review of the First Ten Cases

    C. G. Okwuonu1, O. J. Chimezie2, G. O. Achor3, N. M. Erondu4, C. Ralph-Iheke5, S. Alhassan6

    1INTERNAL MEDICINE/NEPHROLOGY, Federal Medical Centre, Umuahia, Nigeria, 2OPTOMETRY, Federal Medical Centre, Umuahia, Nigeria, 3SURGERY/UROLOGY, Federal Medical Centre, Umuahia, Nigeria, 4ANAESTHESIA, Federal Medical Centre, Umuahia, Nigeria, 5NURSING SERVICES DIVISION, Federal Medical Centre, Umuahia, Nigeria, 6SURGERY/UROLOGY, Aminu Kano Teaching Hospital, Kano, Nigeria

    *Purpose: To assess complication and survival after performance of kidney transplantation in a resource poor setting in Southeast Nigeria*Methods: A retrospective review of transplant registers…
  • 2022 American Transplant Congress

    Covid19 in Pediatric Kidney Transplant Recipients: Incidence, Outcomes, and Response to Vaccine

    A. Moudgil, K. Sgambat, Y. Shi, M. Meyers, C. Petyak, L. Midgley

    Nephrology, Children's National Med. Ctr., Washington, DC

    *Purpose: At the onset of pandemic, no information was available on response of pediatric kidney transplant (PKTX) recipients to COVID19. When COVID19 vaccines became available,…
  • 2022 American Transplant Congress

    Single Center Experience with Acute Kidney Injury Deceased Donor Kidneys from Marginal Donors

    B. K. Sharda, M. Garner, A. Farney, G. Orlando, C. Jay, J. Rogers, A. Daniel, A. Gutierrez, N. Sakhovskaya, R. Stratta

    Atrium Health Wake Forest Baptist Medical Center, Winston Salem, NC

    *Purpose: Many centers will selectively transplant kidneys from standard criteria donors (SCD) with terminal acute kidney injury (AKI). However, there is limited experience with transplanting…
  • 2022 American Transplant Congress

    Infections Following Rejection Therapies in Solid Organ Transplant Recipients

    S. Gupta1, J. Gea-Banacloche2, H. Me3, D. M. Chascsa4, H. R. Vikram2, R. Yaman1, L. Kodali3

    1Internal Medicine, Mayo Clinic, Scottsdale, AZ, 2Infectious Diseases, Mayo Clinic, Phoenix, AZ, 3Transplant Nephrology, Mayo Clinic, Phoenix, AZ, 4Hepatology, Mayo Clinic, Phoenix, AZ

    *Purpose: Infections are known complications of solid-organ transplant. They are most prevalent in the first 12 months after transplant when immunosuppression is at its peak.…
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