Abstracts Archive - Page 49 of 1683 - ATC Abstracts

2022 American Transplant Congress
A Successful Expansion of Donor Liver Supply is Feasible with the Selective Use of Older DCD Livers
M. Finotti, M. Rosenzweig, A. Wall, S. H. Lee, A. Gupta, J. Bayer, H. Fernandez, N. Onaca, R. Ruiz, G. Testa, G. J. McKenna
Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
*Purpose: DCD are a key way to expand the donor pool, yet many centers are hesitant about using anything but the most favorable DCD allografts,…
2022 American Transplant Congress
Inferior Kidney Transplant Outcomes in Young Adults Transplanted as Children
K. Deville, F. Rosenblum, D. R. Kelly, M. Seifert
UAB School of Medicine, Birmingham, AL
*Purpose: Adolescence (age 13-17 years) has been identified as a high-risk age interval for pediatric kidney transplant recipients, with accelerated rates of late acute rejection…
2022 American Transplant Congress
Novel Biopsy-Based Clinical Phenotype Clustering to Predict Kidney Transplant Outcomes
A. Ahmed¹, L. Allegretti², C. Rebello³, B. Kinsella³, K. Guo³, S. Park⁴, J. Friedewald³
¹Chicago Medical School at Rosalind Franklin University, Chicago, IL, ²University of Wisconsin, Madison, WI, ³Northwestern University, Chicago, IL, ⁴Transplant Nephrology, Northwestern University, Chicago, IL
*Purpose: The purpose of this study was to define novel clinical phenotypes based on biopsy results to enhance biomarker discovery.*Methods: Retrospective analysis of kidney biopsy…
2022 American Transplant Congress
Impaired Left Ventricular Global Longitudinal Strain: Clinical Presentation and Outcomes in Liver Transplantation Recipients without Arrhythmia or Structural Heart Disease
M. B. Hammami, J. Grossman, P. Xue, H. Allaham, K. Eagan, S. Gottlieb, C. Hong, L. Wang, C. Bhati, D. Maluf, K. Shetty, N. Urrunaga
University of Maryland School of Medicine, Baltimore, MD
*Purpose: Assess the prevalence and characteristics of patients without arrhythmia or structural heart disease (SHD) but with impaired pre-transplant left ventricular global longitudinal strain (GLS)…
2022 American Transplant Congress
Prevalence of Mycophenolate Mofetil (MMF) Discontinuation and Outcomes in Pediatric Kidney Transplants (PKTX): A PNRC Study
A. Moudgil¹, K. Sgambat¹, E. Benoit², A. Jain³, M. Seifert⁴, C. Katsoufis⁵, L. Harshman⁶, A. Mansuri⁷, M. Somers⁸
¹Nephrology, Children's National Med. Ctr., Washington, DC, ²Nephrology, Boston's Children's Hospital, Boston, MA, ³Nephrology, Wayne State University, Troy, DC, ⁴Nephrology, The University of Alabama, Birmingham, AL, ⁵Nephrology, Holtz Children's Hospital, Miami, FL, ⁶Nephrology, University of Iowa, Iowa City, IA, ⁷Nephrology, Children's Hospital of Georgia, Augusta, GA, ⁸Nephrology, Boston Children's Hospital, Boston, MA
*Purpose: MMF is discontinued in PKTX for various reasons. In this Pediatric Nephrology Research Consortium (PNRC) study, we determined prevalence and reasons for MMF discontinuation…
2022 American Transplant Congress
Apoptotic Exosome-Like Vesicles Aggravate Inflammation and Renal Injury After Ischemia-Reperfusion
I. Kaci¹, S. Lan¹, H. Kim¹, A. Karakeussian Rimbaud¹, F. Migneault¹, J. Turgeon¹, N. Patey², M. Dieudé¹, M. Hébert¹
¹Research Centre, Centre hospitalier de l’Université de Montréal, Montreal, QC, Canada, ²Research Centre, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada
*Purpose: Ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI) and chronic kidney disease (CKD). Damage to microvascular peritubular capillaries (PTC) is…
2022 American Transplant Congress
Investigating RNA Interference-Mediated Inhibition of Liver Ischemia Reperfusion Injury During Liver Preservation
J. E. Buchwald¹, D. Echeverria², J. Sousa², N. McHugh², A. Khvorova², P. N. Martins³
¹RNA Therapeutics Institute, Department of Surgery, University of Massachusetts Chan Medical School, Worcester, MA, ²RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, ³Department of Surgery, University of Massachusetts Chan Medical School, Worcester, MA
*Purpose: Liver transplantation cures acute end-stage and chronic liver diseases, yet current strategies of organ preservation including static cold storage (SCS) and machine perfusion (MP)…
2022 American Transplant Congress
Allo-Sensitization is Increased in Liver Transplant Recipients Following Ischemia-Reperfusion Injury
R. A. Sosa, A. Q. Terry, Y. Yin, B. V. Naini, F. M. Kaldas, R. W. Busuttil, D. W. Gjertson, J. W. Kupiec-Weglinski, E. F. Reed
UCLA, Los Angeles, CA
*Purpose: Recipient sensitization to donor HLA antigens remains an important clinical problem in transplantation, leading to increased wait times to find a compatible donor and…
2022 American Transplant Congress
Impact of Kidney Allocation Change on Low Volume Kidney Transplant Centers
S. Nagaraju¹, S. Vaishnav¹, S. A. Deslich², S. Hanna¹, A. Jones³, J. B. Africa¹
¹Renal Transplant, Charleston Area Medical Center, Charleston, WV, ²Research Associate Senior, Health Services & Outcomes Rsc, Charleston Area Medical Center, Charleston, WV, ³Charleston Area Medical Center, Charleston, WV
*Purpose: Effective March 15, 2021, the OPTN launched a new policy for matching kidney and pancreas transplant candidates with organs from deceased donors. The new…
2022 American Transplant Congress
Longitudinal Analysis of Donor-Derived Cell-Free DNA (dd-cfDNA) in En-Bloc Kidney Transplantation
S. K. Akkina¹, J. Klein², A. Khalil³, G. Shekhtman⁴, S. Patel⁴, N. Agrawal⁴, M. Fei⁴, N. Singh⁵, A. Desai¹
¹Loyola University Medical Center, Maywood, IL, ²University of Kansas Medical Center, Kansas City, KS, ³Dallas Nephrology Associates, Dallas, TX, ⁴CareDx, Brisbane, CA, ⁵Willis Knighton Health System, Shreveport, LA
*Purpose: The longitudinal dd-cfDNA patterns in en-bloc kidney transplant recipients have not been studied. It is unknown how the initial smaller mass of the two…