Abstracts Archive - Page 483 of 1683 - ATC Abstracts

2020 American Transplant Congress
Anti-T Lymphocyte Immunoglobulins versus Basiliximab in Highly Sensitized Kidney-Transplant Patients without Preformed DSAs: The Satir Study
N. Kamar¹, L. Couzi², L. Albano³, A. Durrbach⁴, V. Pernin⁵, L. Esposito¹, M. Lequintrec⁵, P. Merville², A. Del Bello¹
¹Toulouse University Hospital, Toulouse, France, ²Bordeaux University Hospital, Bordeaux, France, ³Nice University Hospital, Nice, France, ⁴Henri Mondor University Hospital, Paris, France, ⁵Montpellier University Hospital, Montpellier, France
*Purpose: Two prospective studies that were performed before the era of highly sensitive solid-phase assays have shown a lower incidence of acute rejection in highly…
2020 American Transplant Congress
Evaluation of the Ability of the Integrative Box (ibox) to Predict Kidney Allograft Survival in a Cohort of Brazilian Patients
K. Linhares¹, M. Raynaud², O. Aubert², C. Lefaucher², G. Gomes¹, C. Peixoto¹, L. Villanueva¹, C. Legendre³, A. Loupy², H. Tedesco-Silva¹
¹Nephrology Division, Hospital do Rim, Sao Paulo, Brazil, ²Research Centre for Organ Transplantation, Université de Paris, Paris, France, ³Research Centre for Organ Transplantation, Hospital do Rim, Sao Paulo, Brazil
*Purpose: Kidney transplantation lacks robust models to predict graft survival. The Paris Transplant Group recently developed the iBox system (NCT03474003), a prediction tool that accurately…
2020 American Transplant Congress
Efficacy of Generic Sofosbuvir and Branded Daclatasvir Compared to Sofosbuvir and Ledipasvir Combination in the Treatment of Genotype 4 Hepatitis C Virus
H. Joharji, D. Alkortas, A. Ajlan, E. Devol, M. Ahmed, F. Aba Al-Khail, H. Elsiesy, M. Alsebayel, H. Alashgar, M. Alquaiz, W. Alhamoudi, A. Almoshishir, A. Aljedai
King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
*Purpose: Genotype 4 HCV is the most common genotype in Saudi Arabia and the Middle East. Management of HCV has shifted in the last few…
2020 American Transplant Congress
Robot-Assisted versus Open Kidney Transplantation for Morbidly Obese Patients
S. D. Lee¹, B. Rawashdeh², E. K. McCracken², L. A. Cantrell³, A. Demirag², A. Agarwal², K. L. Brayman², S. J. Pelletier², J. Oberholzer²
¹Surgery, VCU Health, Richmond, VA, ²Surgery, University of Virginia, Charlottesville, VA, ³Obstetrics and Gynecology, University of Virginia, Charlottesville, VA
*Purpose: Obesity significantly impacts intraoperative and postoperative complications following kidney transplantation. Consequently, many centers deny access to transplantation in patients with a body mass index…
2020 American Transplant Congress
Intra-Lymph Node Injection of Rapamycin-Alloantigen Microparticles Regulates Dendritic Cell Antigen Presentation
C. M. Paluskievicz¹, Y. Xiong¹, W. Piao¹, M. Willson-Shirkey¹, H. Eppler², C. M. Jewell², J. S. Bromberg¹
¹U Maryland, Baltimore, MD, ²U Maryland, College Park, MD
*Purpose: Microparticles (MPs) carrying peptide antigen with immune signals can be directly delivered to lymph nodes (LNs) via intra-LN injections to shape both pro-inflammatory or…
2020 American Transplant Congress
Enough Initial Tacrolimus Blood Concentration is Crucial Even with Additional Everolimus in Corticosteroid Early Withdrawal Regimen for Kidney Transplant Recipients
H. Sasaki¹, T. Tanabe¹, H. Higuchi¹, T. Tsujimoto², H. Harada¹
¹Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan, ²Pharmacy, Sapporo City General Hospital, Sapporo, Japan
*Purpose: Everolimus (EVR) in combination with low-dose calcineurin inhibitor has been demonstrated in clinical trials to have comparable efficacy in low immunological risk kidney transplant…
2020 American Transplant Congress
Renal Transplant Induction Therapy Safety Outcomes Comparison
R. M. Hofmann¹, J. Combs², K. J. Schmidt³, T. Dyckman⁴
¹Nephrology, Renal Associates of West Michigan, Grand Rapids, MI, ²Pharmacy/Transplant, Mercy Health St. Mary's, Grand Rapids, MI, ³Pharmacy, Ferris State University College of Pharmacy, Big Rapids, MI, ⁴Pharmacy, Mercy Health St. Mary's, Grand Rapids, MI
*Purpose: Induction immunosuppression with alemtuzumab and rabbit anti-thymocyte globulin (r-ATG) reduces acute rejection following kidney transplantation. Efficacy is thought to be similar between the agents…
2020 American Transplant Congress
Induction Therapy with Basiliximab versus Thymoglobulin in African-American Kidney Transplant Recipients in the Current Era of Immunosuppression
M. Zachariah¹, I. Mallawaarachchi², N. Meeks³, D. Wright¹, R. Minawala¹, V. Liu¹, J. Rolls⁴, S. Hussein⁴, C. Jarrin⁵
¹Wayne State University, Detroit, MI, ²Division of Biostatistics, University of Virginia, Charlottsville, VA, ³Wayne State University School of Medicine, Detroit, MI, ⁴Surgery, Detroit Medical Center, Detroit, MI, ⁵Infectious Disease, Wayne State University, Detroit, MI
*Purpose: It is now common practice in the transplant community to select induction therapy on the basis of perceived immunological risk for acute rejection which…
2020 American Transplant Congress
Human Live Donor Liver Transplantation is Associated with Pd-l1 Expression on Donor-Exosome-Acquiring Host Dendritic Cells
D. Lema, E. Jankowska-Gan, D. Al-Adra, W. Burlingham
Surgery- Transplantation, University of Wisconsin-Madison, Madison, WI
*Purpose: Liver transplantation (LTx) has been associated with the phenomenon of “cross-dressing” of recipient dendritic cells (DCs) by donor exosome-derived MHC antigens, and acquisition of…
2020 American Transplant Congress
Survival Following Simultaneous Liver-Lung versus Liver Alone Transplantation: Results of the US National Experience
J. Purvis, M. C. Mcleod, B. J. Orandi, D. E. Eckhoff, J. E. Locke, R. M. Cannon
Surgery, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Although simultaneous thoracic-abdominal transplants are undoubtedly complex, there is little data to compare the post-transplant survival between lung-liver transplant (LLT) and liver alone recipients.…