2022 American Transplant Congress
The US Kidney Allocation System Should Not Allocate En Bloc Kidneys from Deceased Donors < 18 Kg as Equivalent to Top 20% KDPI Single Kidneys
1University of Chicago, Chicago, IL, 2Stanford University, Palo Alto, CA
*Purpose: In December 2020, the US Kidney Allocation System (KAS) revised the allocation rules for deceased donors under 18 kg, stating that both kidneys must…2022 American Transplant Congress
Variation in Donor Liver Rejection Rates for Donor Quality Among US Transplant Centers
*Purpose: Optimal utilization of all viable donor livers is a public health imperative. As no standardized criteria exist for assessment of donor quality, differential utilization…2022 American Transplant Congress
The Use of Frailty Assessment to Determine Fitness for Renal Transplant in a Veteran Dialysis Patient Population
*Purpose: Frailty is a medical syndrome characterized by reduced physiologic function and strength. It is associated with an increased risk of mortality, hospital readmission and…2022 American Transplant Congress
Impact of Belatacept Conversion on Renal Function and Donor Specific Antibodies in Renal Transplant Recipients
Northwestern Memorial Hospital, Chicago, IL
*Purpose: Although associated with nephrotoxicity, calcineurin inhibitors (CNI) have historically been the cornerstone of immunosuppression. Belatacept, a co-stimulation blocker, is FDA-approved for de novo use…2022 American Transplant Congress
Impact of Target Tacrolimus Levels on BK Polyomavirus DNAemia and Allograft Rejection Among Pediatric Kidney Transplant Recipients
*Purpose: BK Polyomavirus (BK) DNAemia is a serious and common infectious complication after kidney transplant (KT). We evaluated the impact of targeting lower tacrolimus levels…2022 American Transplant Congress
Non-Invasive Assessment of Hepatic Ischemia-Reperfusion Injury Using Dynamic Contrast Enhanced-MRI and T2 Mapping
*Purpose: Hepatic ischemia-reperfusion injury (IRI) is a consequence of liver transplantation and hepatectomy that varies in severity and clinical significance. The diagnosis is made based…2022 American Transplant Congress
Ultrasound Assessing Donor Kidney Quality in Deceased Donor Kidney Transplantation
*Purpose: We evaluated the role of functional kidney volume using donor kidney ultrasound (US) alone or in combination with other donor factors and parameters appropriate…2022 American Transplant Congress
Novel Biopsy-Based Clinical Phenotype Clustering to Predict Kidney Transplant Outcomes
*Purpose: The purpose of this study was to define novel clinical phenotypes based on biopsy results to enhance biomarker discovery.*Methods: Retrospective analysis of kidney biopsy…2022 American Transplant Congress
Association Between Increased Overweight at First Year After Kidney Transplantation and Long-Term Kidney Graft Outcome
*Purpose: The obesity is increasing in chronic kidney disease patients and associated with poor renal outcome. The role of inflammation within the adipose tissue in…2022 American Transplant Congress
Recipient Treatment with Anti-CD122 mAb Prolongs Kidney Allograft Survival During Antibody-Mediated Rejection without Impacting NK Cell Activation within the Graft
Cleveland Clinic, Cleveland, OH
*Purpose: Dysregulated donor-specific antibody (DSA) responses are induced in B6.CCR5-/- mice transplanted with complete MHC mismatched kidney allografts and are required for rejection of the…
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