ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Granulocyte Colony Stimulating Factor: Trigger of Rejection in Lung Transplantation?

    K. Walter1, M. Patti1, S. Khalid2, L. Kemp1, L. J. Lobo3, R. Coakley3, S. Krishnan3, C. T. Doligalski1

    1University of North Carolina Medical Center, Chapel Hill, NC, 2Eshelman School of Pharmacy, Chapel Hill, NC, 3Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC

    *Purpose: Granulocyte colony stimulating factor (GCSF) is a management strategy for post-transplant neutropenia, but may increase the risk of rejection in lung transplant recipients (LTRs).…
  • 2020 American Transplant Congress

    Alternate Triazole Therapy for Breakthrough Invasive Fungal Disease in Lung Transplant Recipients on Triazole Prophylaxis

    A. Abbas, H. Hassouna, F. Marco Canosa, K. D. Brizendine

    Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: Invasive fungal diseases (IFD) are a leading cause of infection related morbidity and mortality in lung transplant (LT) recipients. Data regarding outcomes of breakthrough…
  • 2020 American Transplant Congress

    Impact of the 2015 LAS Revisions on Lung Candidates with Pulmonary Vascular Disease

    K. Lindblad1, R. Goff1, K. Chan2

    1UNOS, Richmond, VA, 2University of Michigan, Ann Arbor, MI

    *Purpose: On February 19, 2015 a major revision to the Lung Allocation Score (LAS) was implemented with the goal of more accurately reflecting waitlist urgency…
  • 2020 American Transplant Congress

    Is Total Ischemic Time a Measure of OPTN Efficiency? Monitoring the Impact of Lung Allocation Policy on Ischemic Time

    A. M. Placona1, R. R. Goff1, P. Shay2, B. Carrico1

    1United Network for Organ Sharing, Richmond, VA, 2Health Administration, Trinity University, San Antonio, TX

    *Purpose: There is concern that the shift to circle based organ allocation policy may increase coordination costs. Within both public comment and the peer reviewed…
  • 2020 American Transplant Congress

    Outpatient Treatment of Paramyxovirus with Oral Ribavirin is Safe and Effective in Lung Transplant Recipients

    A. W. Rogers1, B. J. Pierce1, C. Pham1, J. T. Swan1, H. J. Huang2

    1Department of Pharmacy, Houston Methodist Hospital, Houston, TX, 2Department of Medicine, Houston Methodist Hospital, Houston, TX

    *Purpose: Respiratory paramyxovirus infections present an increased risk to lung transplant recipients (LTRs), including rapid decline in graft function and immunologic sequelae such as rejection…
  • 2020 American Transplant Congress

    Alterations in Left Ventricular Wall Thickness after Cardiac Transplantation

    C. K. Alvarez, O. Saeed, S. R. Patel, E. Borukhov, U. Jorde

    Advanced Heart Failure, Transplant and Mechanical Circulatory Support, Montefiore Medical Center, Albert Einstein, Bronx, NY

    *Purpose: We investigated changes in cardiac wall thickness of donor hearts over time, including the peri-operative OHT period (within 4 days after transplantation) and up…
  • 2020 American Transplant Congress

    Monitoring the Removal of Donation Service Area from Lung Allocation

    R. R. Goff1, R. Daly2, E. D. Lease3

    1Research, United Network for Organ Sharing, Richmond, VA, 2Mayo Clinic, Rochester, MN, 3University of Washington, Seattle, WA

    *Purpose: In 2017 the Organ Procurement and Transplantation Network (OPTN) altered US lung allocation policy by replacing the donor service area (DSA) with a 250…
  • 2020 American Transplant Congress

    Comparison of Stanford Integrated Psychosocial Assessment for Transplantation Scores to Medication Adherence Assessment Findings in Kidney Transplant Candidates Undergoing Living Donor Transplant

    J. Trofe-Clark1, G. Malat1, M. Norris1, M. Bleicher2, E. Smith3, D. Sawinski2, R. Weinrieb4, R. Bloom2

    1Pharmacy, Hospital of Univ of Pennsylvania, Philadelphia, PA, 2Renal Division, Univ of Pennsylvania, Philadelphia, PA, 3Social Work, Hosp of Univ of Pennsylvania, Philadelphia, PA, 4Pyschiatry, Univ of Pennsylvania, Philadelphia, PA

    *Purpose: The Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT) is a standardized, evaluation tool intended to assess psychosocial health in organ transplant candidates. The purpose…
  • 2020 American Transplant Congress

    The Negative Impact of Inherent Oxidative Stress in Marginal Lungs on Ex Vivo Lung Perfusion

    K. Noda1, B. J. Philips1, M. Velayutham2, T. Harano1, P. Reck dos Santos1, S. Shiva2, P. G. Sanchez1

    1Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, 2Department of Medicine, University of Pittsburgh, Pittsburgh, PA

    *Purpose: Identifying good quality grafts within the donor pool, ex vivo lung perfusion (EVLP) opens another window to evaluate grafts initially declined with marginal quality…
  • 2020 American Transplant Congress

    A Large Animal Model of Ex-Vivo Lung Perfusion as a Platform to Deliver Therapeutic Agents to Lungs Before Lung Transplant

    T. M. Egan1, B. Haithcock1, M. H. Ali1, J. W. Blackwell1, B. Masuodi1, S. Shipley2, T. Long3, A. Akerman1, S. Montgomery4, H. Yuan5, P. Stewart6, J. Potenziano7, C. Sekaran7, R. Fitch7

    1Surgery, UNC at Chapel Hill, Chapel Hill, NC, 2Department of Pathology and Laboratory Medicine, UNC at Chapel Hill, Chapel Hill, NC, 3Pathology and Laboratory Medicine,, UNC at Chapel Hill, Chapel Hill, NC, 4Pathology and Laboratory Medicine, UNC at Chapel Hill, Chapel Hill, NC, 5Radiology, UNC at Chapel Hill, Chapel Hill, NC, 6Gillings Global School of Public Health, UNC at Chapel Hill, Chapel Hill, NC, 7Mallinckrodt Pharmaceuticals, Hazelwood, MO

    *Purpose: Ex-vivo lung perfusion (EVLP) has been used to evaluate lung function before lung transplant (LT). We used EVLP to expose lungs recovered 6 hours…
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