ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Heart Transplantation Outcomes in Patients with Marfan Syndrome: A UNOS Registry Analysis

    P. Genyk1, K. Yang1, J. Pizula1, A. Lee1, D. Miklin1, S. Shah1, S. Nuno1, S. Hashmi1, J. Nattiv1, A. Kiankhooy1, L. Grazette1, M. Fong1, J. Rahman1, K. Pandya1, A. Vaidya1, D. Vucicevic2, J. Li1, P. Kingsford1, P. Banankhah1, A. Wolfson3, G. Liu1, R. Chand4, E. Depasquale1

    1Keck Medicine of USC, Los Angeles, CA, 2Newark Beth-Israel Medical Center, Newark, NJ, 3University of Arizona Sarver Heart Center, Tucson, AZ, 4Harbor-UCLA Medical Center, Torrance, CA

    *Purpose: Marfan syndrome (MS) is an autosomal dominant connective tissue disorder due to a defect in the fibrillin-1 gene. MS patients can develop a discrete…
  • 2020 American Transplant Congress

    Foxp3+ Innate and TGF-ß+ Adaptive Regulatory Immune Cells in Quilty Lesions are Associated with Acceptance of Heart Allograft

    S. A. Moore, C. K. Metter, Q. Cai, J. R. Torrealba

    University of Texas Southwestern Medical Center, Dallas, TX

    *Purpose: To evaluate the cellular composition of Quilty lesions in heart transplant biopsies and their association with acceptance or rejection of cardiac allografts.*Methods: This study…
  • 2020 American Transplant Congress

    Impact of Alemtuzumab Induction on Cardiac Allograft Vasculopathy in Orthotopic Heart Transplant Recipients

    M. Plazak1, X. Gao2, S. Gale2, B. Reed2, R. Madathil1, S. Hammad1, B. Ravichandran1

    1University of Maryland Medical Center, Baltimore, MD, 2University of Maryland School of Pharmacy, Baltimore, MD

    *Purpose: Cardiac allograft vasculopathy (CAV) is impacted by acute rejection and ultimately limits long-term survival of orthotopic heart transplant (OHT) recipients, thus there is interest…
  • 2020 American Transplant Congress

    The Reperfusion Response in Plasma of Combined Heart/ Lung Transplanted Patients is Guided by Heart-Associated Cytokine Patterns on Contrast to the Ischemic Injury in Perfusion Solutions Following a Lung-Associated Pattern

    C. Falk1, J. Kühne2, L. Radomsky2, F. Wandrer2, B. Wiegmann3, N. Ledwoch2, J. Keil2, K. Beushausen2, F. Ius3, W. Sommer3, S. Rojas-Hernandez3, I. Tudorache3, A. Haverich3, G. Warnecke3

    1MHH, Institute of Transplant Immunology, Hannover, Germany, 2Institute of Transplant Immunology, Hannover Medical School MHH, Hannover, Germany, 3Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School MHH, Hannover, Germany

    *Purpose: Organ-specific differences are discussed for ischemia/reperfusion injury (IRI) in cardiothoracic transplantation but rarely compared directly in a clinical setting. Therefore, we compared a cohort…
  • 2020 American Transplant Congress

    Post Heart Transplant Outcomes for Patients with Cardiac Sarcoidosis

    G. S. Liu1, E. C. DePasquale1, A. M. Wolfson2, R. R. Chand3, P. Banankhah1, J. Nattiv1, A. D. Salimbangon4, P. A. Genyk1, P. A. Kingsford1, J. P. Li1, D. Vucicevic5, K. Pandya1, J. Rahman1, M. Fong1, A. S. Vaidya1

    1Keck Medicine of USC, Los Angeles, CA, 2University of Arizona Sarver Heart Center, Tucson, AZ, 3Harbor-UCLA Medical Center, Los Angeles, CA, 4UCLA Medical Center, Los Angeles, CA, 5Newark Beth Israel Medical Center, Newark, NJ

    *Purpose: Cardiac sarcoidosis (CS) is a known etiology of end-stage dilated, hypertrophic, or arrhythmogenic cardiomyopathies requiring heart transplantation (HT). We sought to evaluate the long-term…
  • 2020 American Transplant Congress

    The Effect of UNOS Donor Policy Change on Ischemic Time and the Effects on Mortality in Heart Transplantation

    A. Lee1, K. Yang1, G. Liu1, C. Lum2, A. D. Salimbangon3, R. R. Chand4, P. Banankhah1, P. Genyk1, P. Kingsford1, J. Li1, J. Li1, D. Vucicevic5, K. Pandya1, J. Rahman1, M. Fong1, L. Grazette1, A. Kiankhooy1, J. [email protected]1, S. Hashmi1, A. Gong1, J. Pizula1, D. Miklin1, S. Shah1, A. Vaidya1, A. Wolfson6, E. Depasquale1

    1Keck Medicine of USC, Los Angeles, CA, 2The Queens Medical Center, Honolulu, HI, 3UCLA Medical Center, Los Angeles, CA, 4Harbor-UCLA Medical Center, Los Angeles, CA, 5Newark Beth-Israel Medical Center, Newark, NJ, 6University of Arizona Sarver Heart Center, Tuscon, AZ

    *Purpose: In light of the recent change in the UNOS allocation policy, we sought to evaluate the impact of ischemic time on mortality.*Methods: Using the…
  • 2020 American Transplant Congress

    Effects of Donor Heavy Alcohol Use on Post-Heart Transplant Outcomes: Time to Abstain?

    J. Patel, M. Kittleson, D. Chang, E. Kransdorf, D. Geft, A. Shen, K. Nishihara, G. Jamero, L. Czer, F. Esmailian, J. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: Donors with a history of heavy alcohol use have been suspected to possibly harbor a subclinical alcoholic cardiomyopathy with limited cardiac reserve. This problem…
  • 2020 American Transplant Congress

    Heart Transplantation Outcomes in Multiorgan Transplants

    P. Kingsford1, J. P. Li1, C. J. Lum2, A. Salimbangon3, G. Liu1, A. M. Wolfson4, R. R. Chand5, P. Banankhah1, P. A. Genyk1, D. Vucicevic6, K. Pandya1, J. Rahman1, M. Fong1, L. Grazette1, A. Kiankhooy1, J. Nattiv1, S. Hashmi1, S. B. Nuno1, J. Pizula1, D. J. Miklin1, A. E. Lee1, K. Yang1, S. Shah1, A. S. Vaidya1, E. C. DePasquale1

    1LAC+USC, Los Angeles, CA, 2The Queens Medical Center, Honolulu, HI, 3UCLA Medical Center, Los Angeles, CA, 4University of Arizona Sarver Heart Center, Tucson, AZ, 5Harbor-UCLA Medical Center, Los Angeles, CA, 6Newark Beth-Israel, Los Angeles, CA

    *Purpose: We sought to elucidate the differences in outcomes between patients undergoing Heart-Lung (HL) Heart-Lung-Kidney (HLK) and Heart-Lung-Liver (HLL) multiorgan transplantation.*Methods: Using the UNOS registry,…
  • 2020 American Transplant Congress

    The Frequency of De Novo DSA in the Years Following Heart Transplantation

    A. Shen, J. Patel, M. Kittleson, D. Chang, E. Kransdorf, D. Geft, K. Nishihara, L. Czer, F. Esmailian, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: The timing of the development of donor specific antibody (DSA) after heart transplantation is not clear. De novo DSA has been reported to be…
  • 2020 American Transplant Congress

    Alterations in Left Ventricular Wall Thickness after Cardiac Transplantation

    C. K. Alvarez, O. Saeed, S. R. Patel, E. Borukhov, U. Jorde

    Advanced Heart Failure, Transplant and Mechanical Circulatory Support, Montefiore Medical Center, Albert Einstein, Bronx, NY

    *Purpose: We investigated changes in cardiac wall thickness of donor hearts over time, including the peri-operative OHT period (within 4 days after transplantation) and up…
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