Abstracts Archive - Page 47 of 1683 - ATC Abstracts

2022 American Transplant Congress
Treatment Modality and Outcomes of Antibody-Mediated Rejection in Pediatric Kidney Transplant Recipients: The PARAMOUr Study
R. Engen¹, A. Jain², N. Hayde³, A. Mansuri⁴, M. Kallash⁵, S. McEwen⁶, R. Garro⁷, C. Peterson⁸, R. Zahr⁹, L. Harshman¹⁰, D. Puliyanda¹¹, S. Solomon¹², K. Twombley¹³, I. Ashoor¹⁴
¹Pediatrics, University of Wisconsin Madison, Madison, WI, ²Wayne State University, Detroit, MI, ³Albert Einstein College of Medicine, New York, NY, ⁴Augusta University, Augusta, GA, ⁵The Ohio State University, Columbus, OH, ⁶University of Minnesota, Minneapolis, MN, ⁷Emory University, Atlanta, GA, ⁸University of Utah Health, Salt Lake City, UT, ⁹The University of Tennessee Health Science Center, Memphis, TN, ¹⁰University of Iowa, Iowa City, IA, ¹¹Cedars-Sinai Medical Center, Los Angeles, CA, ¹²New York Medical College, Valhalla, NY, ¹³Medical University of South Carolina, Charleston, SC, ¹⁴Louisiana State University, New Orleans, LA
*Purpose: Antibody-mediated rejection (AMR) is the leading cause of graft failure in kidney transplantation, but evidence for effective treatments is limited.*Methods: PARAMOUr is a retrospective…
2022 American Transplant Congress
Generation and Functional Characterization of Bio-Engineered Livers for Heterotopic Implantation in Porcine Model of Acute Liver Failure
A. A. Katane¹, B. P. Amiot², A. R. Stumbras¹, A. Mendenhall¹, N. R. Palumbo¹, A. C. Donepudi¹, J. J. Ross¹, S. L. Nyberg³
¹Miromatrix Medical Inc, Eden Prairie, MN, ²Department of Surgery, Mayo Clinic, Rochester, MN, ³William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN
*Purpose: Liver transplantation has shown to be an effective therapy for the end-stage liver diseases (ESLD). However, as donor organ shortages increase, organ engineering technology…
2022 American Transplant Congress
Final Flow and Resistance During Cold Pulsatile Perfusion Preservation Do Have Value in Prediction of Deceased Donor Graft Survival After Adjusting for KDPI
D. S. Keith, E. Lessmann
Kidney Transplant, Sacred Heart Hospital, Pensacola, FL
*Purpose: To determine whether cold pulsatile perfusion preservation (CPPP) parameters of flow and resistance provide additional data regarding deceased donor kidney graft survival after adjusting…
2022 American Transplant Congress
Early Experience with OmniGraf® Biomarker Surveillance in Kidney Transplant Patients in the First-Year Post-Transplant and Beyond
V. Paramasivam¹, W. Ally², B. Sivakumar³, B. Greco¹, M. Germain¹
¹Baystate Medical Center, Springfield, MA, ²Eurofins Transplant Genomics, Framingham, MA, ³Dartmouth College, Hanover, NH
*Purpose: Non-invasive rejection biomarkers continue to evolve with recent data supporting the use of combined gene expression and donor derived cell-free DNA (dd-cfDNA) in kidney…
2022 American Transplant Congress
The US Kidney Allocation System Should Not Allocate En Bloc Kidneys from Deceased Donors < 18 Kg as Equivalent to Top 20% KDPI Single Kidneys
W. F. Parker¹, A. Gallo², L. Ross¹
¹University of Chicago, Chicago, IL, ²Stanford University, Palo Alto, CA
*Purpose: In December 2020, the US Kidney Allocation System (KAS) revised the allocation rules for deceased donors under 18 kg, stating that both kidneys must…
2022 American Transplant Congress
Variation in Donor Liver Rejection Rates for Donor Quality Among US Transplant Centers
M. Anderson¹, T. Gilbert², M. Englesbe¹, S. Waits¹
¹Michigan Medicine Transplant Center, Ann Arbor, MI, ²University of Michigan Medical School, Ann Arbor, MI
*Purpose: Optimal utilization of all viable donor livers is a public health imperative. As no standardized criteria exist for assessment of donor quality, differential utilization…
2022 American Transplant Congress
The Use of Frailty Assessment to Determine Fitness for Renal Transplant in a Veteran Dialysis Patient Population
M. Samra¹, A. Wadhwa¹, T. Markossian², R. Lopez-Soler³
¹Medicine, Edward Hine Jr., VA Medical Center, Hines, IL, ²Edward Hine Jr., VA Medical Center, Hines, IL, ³Surgery, Edward Hines VA Jr.,VA Medical Center, Chicago, IL
*Purpose: Frailty is a medical syndrome characterized by reduced physiologic function and strength. It is associated with an increased risk of mortality, hospital readmission and…
2022 American Transplant Congress
Impact of Belatacept Conversion on Renal Function and Donor Specific Antibodies in Renal Transplant Recipients
E. R. Brown, K. Cunningham, K. Paplaczyk, C. Dagostino, C. Kane, A. Shetty
Northwestern Memorial Hospital, Chicago, IL
*Purpose: Although associated with nephrotoxicity, calcineurin inhibitors (CNI) have historically been the cornerstone of immunosuppression. Belatacept, a co-stimulation blocker, is FDA-approved for de novo use…
2022 American Transplant Congress
Impact of Target Tacrolimus Levels on BK Polyomavirus DNAemia and Allograft Rejection Among Pediatric Kidney Transplant Recipients
H. Huang¹, P. Winterberg¹, R. George¹, A. Serluco², R. Liverman², I. Yildirim³, R. Garro¹
¹Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, ²Children's Healthcare of Atlanta, Atlanta, GA, ³Yale University School of Medicine, New Haven, CT
*Purpose: BK Polyomavirus (BK) DNAemia is a serious and common infectious complication after kidney transplant (KT). We evaluated the impact of targeting lower tacrolimus levels…
2022 American Transplant Congress
Non-Invasive Assessment of Hepatic Ischemia-Reperfusion Injury Using Dynamic Contrast Enhanced-MRI and T2 Mapping
O. C. Rodriguez¹, J. R. Liggett², J. Kang², K. Loh², Y. Lee¹, N. Sang¹, B. He¹, Y. Cui², K. Oza², D. Kwon³, B. Kallakury³, T. Fishbein², W. Cui², K. Khan², C. Albanese¹, A. Kroemer²
¹Lombardi Comprehensive Cancer Center and the Center for Translational Imaging, Georgetown University Medical Center, Washington, DC, ²MedStar Georgetown Transplant Institute, Washington, DC, ³Pathology, MedStar Georgetown University Hospital, Washington, DC
*Purpose: Hepatic ischemia-reperfusion injury (IRI) is a consequence of liver transplantation and hepatectomy that varies in severity and clinical significance. The diagnosis is made based…