ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Time-Dependent Blood Eosinophilia Count Increases the Risk of Kidney Allograft Rejection

    L. Colas1, L. Bui2, C. Kerleau3, M. Lemdani4, K. Autain-Renaudin5, A. Magnan6, M. Giral3, S. Brouard1

    1CRT2I, Université de Nantes, Nantes, France, 2Service de Néphrologie, Centre Hospitalier de Mouscron, Mouscron, Belgium, 3Service de Néphrologie et Immunologie Clinique, CHU de Nantes, Nantes, France, 4Département de Biomathématiques, Université de Lilles, Lilles, France, 5Service d'Anatomie et Cytologie Pathologique, CHU de Nantes, Nantes, France, 6INRAe UMR 0892, Université de Versailles Saint-Quentin Paris-Saclay, Paris, France

    *Purpose: There is growing evidence that type 2 immune effectors (immunoglobulin E, eosinophils, mast cells/basophils) play a role in autoimmune disorders and solid organ transplantation.…
  • 2022 American Transplant Congress

    Access to Pediatric Kidney Transplant: The Impact of Mental Health Diagnoses and Social Determinants of Health

    E. Blanchette1, E. Benz1, J. Armendariz1, K. McKinnon1, M. Chandran2, E. S. Christofferson1, M. Bisek1, M. Bock1

    1Children's Hospital Colorado, Aurora, CO, 2Pharmacy, UNC Hospitals, Chapel Hill, NC

    *Purpose: Limited and delayed access to kidney transplant (KT) has been associated with characteristics of adult KT candidates, including mental health (MH) diagnoses, negative social…
  • 2022 American Transplant Congress

    What If Only Days After Dialysis Counted Towards Kidney Candidates’ Qualified Waiting Times?

    G. R. Vece, K. Lindblad, M. Stuart, B. Carrico, D. Stewart, D. Klassen, S. Diallo

    Research, United Network for Organ Sharing, Richmond, VA

    *Purpose: Current kidney policy allows patients who have not yet initiated dialysis to qualify for allocation priority based on the time since a recorded eGFR…
  • 2022 American Transplant Congress

    Impact of Graft Type, Presence and Type of Inflammatory Bowel Disease on Outcomes Following Liver Transplantation for Primary Sclerosing Cholangitis

    S. Kumar1, S. Lin2, J. D. Schold3

    1Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, 2Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, 3Center for Populations Health Research, Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: In Primary sclerosing cholangitis (PSC), concerns exist regarding outcomes following donation after circulatory death (DCD) liver transplantation (LT) due to risk of ischemic cholangiopathy…
  • 2022 American Transplant Congress

    Association Between Allograft Gene Expression and Acute Cellular Rejection Grade in Heart Transplant Recipients

    A. Kao1, K. Haffey2, K. T. Gondi3, J. Linard2, C. Knutson2, K. Morgan2, L. Teterina2, S. Williams2, K. Oreschak4, H. Zhang4

    1St. Luke's Health System Kansas City Mid America Heart Institute, Kansas City, MO, 2St. Luke's, Kansas City, MO, 3University of Michigan, Ann Arbor, MI, 4CareDx, South San Francisco, CA

    *Purpose: Endomyocardial biopsy (EMB) remains the gold standard in acute rejection (AR) surveillance in heart transplantation (HT) despite interpretation subjectivity and low concordance rates between…
  • 2022 American Transplant Congress

    Outcomes Following Renal Transplant with Hepatitis C Viremic Donors in an Elderly Veteran Population with Preemptive Mayvret Therapy

    R. Lopez-Soler1, A. Thorndyke1, C. Trotter1, A. Abadier2, M. Samra1

    1Surgery, Transplantation, Edward Hines Jr. Veterans Administration Hospital, Hines, IL, 2Surgery, Loyola University School of Medicine, Maywood, IL

    *Purpose: Overall mortality on the kidney transplant waiting list is higher for older diabetic patients. The average age of waitlisted veteran patients is 64, with…
  • 2022 American Transplant Congress

    Treatment Modality and Outcomes of Antibody-Mediated Rejection in Pediatric Kidney Transplant Recipients: The PARAMOUr Study

    R. Engen1, A. Jain2, N. Hayde3, A. Mansuri4, M. Kallash5, S. McEwen6, R. Garro7, C. Peterson8, R. Zahr9, L. Harshman10, D. Puliyanda11, S. Solomon12, K. Twombley13, I. Ashoor14

    1Pediatrics, University of Wisconsin Madison, Madison, WI, 2Wayne State University, Detroit, MI, 3Albert Einstein College of Medicine, New York, NY, 4Augusta University, Augusta, GA, 5The Ohio State University, Columbus, OH, 6University of Minnesota, Minneapolis, MN, 7Emory University, Atlanta, GA, 8University of Utah Health, Salt Lake City, UT, 9The University of Tennessee Health Science Center, Memphis, TN, 10University of Iowa, Iowa City, IA, 11Cedars-Sinai Medical Center, Los Angeles, CA, 12New York Medical College, Valhalla, NY, 13Medical University of South Carolina, Charleston, SC, 14Louisiana State University, New Orleans, LA

    *Purpose: Antibody-mediated rejection (AMR) is the leading cause of graft failure in kidney transplantation, but evidence for effective treatments is limited.*Methods: PARAMOUr is a retrospective…
  • 2022 American Transplant Congress

    Generation and Functional Characterization of Bio-Engineered Livers for Heterotopic Implantation in Porcine Model of Acute Liver Failure

    A. A. Katane1, B. P. Amiot2, A. R. Stumbras1, A. Mendenhall1, N. R. Palumbo1, A. C. Donepudi1, J. J. Ross1, S. L. Nyberg3

    1Miromatrix Medical Inc, Eden Prairie, MN, 2Department of Surgery, Mayo Clinic, Rochester, MN, 3William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN

    *Purpose: Liver transplantation has shown to be an effective therapy for the end-stage liver diseases (ESLD). However, as donor organ shortages increase, organ engineering technology…
  • 2022 American Transplant Congress

    Final Flow and Resistance During Cold Pulsatile Perfusion Preservation Do Have Value in Prediction of Deceased Donor Graft Survival After Adjusting for KDPI

    D. S. Keith, E. Lessmann

    Kidney Transplant, Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine whether cold pulsatile perfusion preservation (CPPP) parameters of flow and resistance provide additional data regarding deceased donor kidney graft survival after adjusting…
  • 2022 American Transplant Congress

    Early Experience with OmniGraf® Biomarker Surveillance in Kidney Transplant Patients in the First-Year Post-Transplant and Beyond

    V. Paramasivam1, W. Ally2, B. Sivakumar3, B. Greco1, M. Germain1

    1Baystate Medical Center, Springfield, MA, 2Eurofins Transplant Genomics, Framingham, MA, 3Dartmouth College, Hanover, NH

    *Purpose: Non-invasive rejection biomarkers continue to evolve with recent data supporting the use of combined gene expression and donor derived cell-free DNA (dd-cfDNA) in kidney…
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