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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Are Autoimmune Conditions Disadvantaged Compared to Alcoholic Cirrhosis and Hepatocellular Carcinoma?

    S. S. Keeling

    Baylor College of Medicine, Houston, TX

    *Purpose: Orthotopic liver transplantation (OLT) is a lifesaving therapy for patients with irreversible liver damage caused by autoimmune liver diseases (ALD) including autoimmune hepatitis (AIH),…
  • 2022 American Transplant Congress

    Single Cell RNAseq Analysis of Liver Transplant Rejection Reveals Highly Restricted TCR Clonal Expansion of Tissue-Resident Memory CD8+ T Cells That Persist Despite Corticosteroids and ATG Therapy

    A. L. Peters1, G. Begum1, K. Roskin2, E. Woodle3, D. Hildeman4

    1Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Department of Bioinformatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Department of Surgery, University of Cincinnati, Cincinnati, OH, 4Department of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    *Purpose: Conventional therapy for liver transplant rejection (corticosteroids and ATG) has remained unchanged for six decades, and is not infrequently met with treatment failure. Here,…
  • 2022 American Transplant Congress

    Tele-Health Implementation During Covid19 Pandemic in Liver Transplant Population: A Focus on Medication Adherence, Patient Satisfaction, Clinical Outcomes and Possible Cost Impact

    H. Joharji, S. Alghamdi, S. Alqahtani, M. F. Janju, J. Khader, D. Alissa, A. Aljedai, D. Alkortas, K. Bezaizi, D. Broering, A. Ajlan, W. K. Al-Hamoudi, E. Devol, A. Albinmosa, S. Alabbad, Z. Alabdulkarim, A. Zidan, R. Alamawi, E. Alshammari, E. Alharthi, D. Al-Anazi, A. Almalki, M. Alasmari

    Organ Transplant Center of Excellence, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

    *Purpose: The COVID-19 pandemic affected many aspects of health care, including the provision of care in ambulatory care clinics, necessitating the utilization of telehealth. For…
  • 2022 American Transplant Congress

    The Development of a Scientific Registry of Transplant Recipients Data Query Tool: A Human-Centered Design Process

    C. Schaffhausen1, A. Hart2, C. S. Zinner3, A. K. Israni2, J. Snyder1

    1Hennepin Healthcare Research Institute, Minneapolis, MN, 2Hennepin Healthcare (HHS) / University of Minnesota (UMN), Minneapolis, MN, 3Accenture Federal Services, Washington, DC

    *Purpose: The Scientific Registry of Transplant Recipients (SRTR) provides national transplant data in various forms, including the OPTN/SRTR Annual Data Report (ADR). The ADR includes…
  • 2022 American Transplant Congress

    The Correlation Between Kidney Donor Risk Index, Kidney Graft Function and Histological Changes in Early Post-Transplant Renal Biopsy

    N. Slabiak-Blaz, A. Kujawa-Szewieczek, A. Kolonko, H. Karkoszka, A. Wiecek, G. Piecha

    Department of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland

    *Purpose: An appropriate assessment of donor organ quality is crucial to optimize the kidney allocation and improve the long-term outcomes. Kidney Donor Risk Index (KDRI),…
  • 2022 American Transplant Congress

    CD8+ T Cells Differentiate into a CD43-expressing Effector Population After Transplantation

    G. Cohen, M. A. Kallarakal, S. M. Krummey

    Department of Pathology, Johns Hopkins University, Baltimore, MD

    *Purpose: Despite a significantly reduced toxicity profile and improved long-term graft function versus calcineurin inhibitors, widespread adaptation of belatacept (CTLA-4 Ig) has been limited due…
  • 2022 American Transplant Congress

    Donor-Derived Cell-Free DNA Testing in Kidney Transplantation: Do One-Month Values Have Any Prognostic Significance?

    B. K. Sharda1, M. Garner1, A. Farney1, G. Orlando2, J. Rogers2, C. Jay3, A. Daniel1, A. Guiterrez1, N. Sakhovskaya1, R. Stratta1

    1ATRIUM HEALTH Wake Forest Baptist Medical Center, Winston Salem, NC, 2Wake Forest Baptist Medical Center, Winston Salem, NC, 3Wake Forest Baptist Health, Winston-Salem, NC

    *Purpose: Plasma-based donor-derived cell-free DNA (dd-cfDNA) assays have been proposed as an alternative to percutaneous renal allograft biopsy which is the current gold standard for…
  • 2022 American Transplant Congress

    COVID-19 Infection Post-Transplant: What is the Collateral Damage to the Graft? A Case for Pre-Transplant Vaccination

    A. Fabick1, E. Overly1, V. Rao2, V. Rohan3, N. Patel1, D. DuBay3, C. Candland3, N. Pilch1

    1Department of Pharmacy, Medical University of South Carolina, Charleston, SC, 2Department of Transplant Nephrology, Medical University of South Carolina, Charleston, SC, 3Department of Transplant Surgery, Medical University of South Carolina, Charleston, SC

    *Purpose: COVID-19 produces an unpredictable immune reaction and is challenging to manage during active infection and post-infection, in kidney transplant (KTX) recipients. The first peak…
  • 2022 American Transplant Congress

    Towards Bionic Organs: Biocompatibility Of Newly Developed Porcine Decm-based Hydrogels.

    M. Rachalewski, M. Klak, D. Ujazdowska, P. Cywoniuk, T. Dobrzanski, G. Tymicki, K. Kosowska, T. Bryniarski, A. Berman, M. Wszola

    Foundation of Research and Science Development, Warsaw, Poland

    *Purpose: There is a growing interest in fabrication of bioinks which on one hand biocompatible and on the other hand possess mechanical properties which would…
  • 2022 American Transplant Congress

    Living Related Kidney Donation for Alport Syndrome Spectrum: Long-Term Outcomes

    Y. Caliskan1, A. B. Dirim2, S. Safak2, B. Yelken3, A. Velioglu4, A. Yildiz5, O. A. Oto2, N. Guller2, H. Yazici2, A. Ersoy5, A. Turkmen3, K. L. Lentine1

    1Saint Louis University, Saint Louis, MO, 2Istanbul University, Istanbul, Turkey, 3Koc University Hospital, Istanbul, Turkey, 4Marmara University, Istanbul, Turkey, 5Uludag University, Bursa, Turkey

    *Purpose: Data to guide the evaluation of living related donor (LRD) candidates for kidney transplant recipients with Alport syndrome (AS) spectrum are limited. We examined…
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