2020 American Transplant Congress
Microbiota Modulates Ischemia-Reperfusion Injury in Mouse Liver Transplantation
*Purpose: Ischemia-reperfusion injury (IRI) is a major risk factor in orthotopic liver transplantation (OLT). As host microbiota may associate with health or disease, antibiotics (Abx)…2020 American Transplant Congress
The Histological Picture of Indication Biopsies in the First Days after Renal Transplantation
Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
*Purpose: In preclinical studies, ischemia reperfusion injury and older donor age are associated with renal inflammation in the early phase after transplantation. In human kidney…2020 American Transplant Congress
Ex Vivo Pumping Through an OPO’s Eyes
*Purpose: A single, large organ procurement organization (OPO) sought to document the use of extra-renal ex vivo pumping in the management of the deceased donor…2020 American Transplant Congress
Development of a Split Liver Machine Perfusion Protocol to Provide Comparative Controls in Assessing Therapeutic Interventions
*Purpose: Ex situ donor liver machine perfusion is developing into a promising tool to test organ viability prior to transplantation and vehicle to assess novel…2020 American Transplant Congress
The Scenario of Delayed Graft Function in Brazil
*Purpose: Unicenter Brazilian studies reported high incidences (50-70%) of delayed graft function (DGF). This is a multicenter Brazilian study aimed to evaluate the incidence, the…2020 American Transplant Congress
The Association between Donor Hypothermia and Allograft Outcomes in Liver and Kidney Transplantation
Temple University School of Medicine, Philadelphia, PA
*Purpose: Traumatic brain injury patients benefit from mild to moderate hypothermia (32-35 °C); and in patients with cardiac arrest, stroke, and asphyxia, hypothermia is and…2020 American Transplant Congress
Inequitable Access to Living Donor Kidney Transplantation in Black and Asian Minority Ethnic Groups in the UK: A Single Centre Cross-Sectional Cohort Study
Guy's and St. Thomas' Hospital, London, United Kingdom
*Purpose: Black, Asian and Minority Ethnic (BAME) communities constitute 11% of the UK population, yet represent 31% of the national kidney transplant waiting list. Moreover,…2020 American Transplant Congress
The Clinical Impact of HCV D+/r- Kidney Transplantation
1Lahey Clinic, Burlington, MA, 2Transplantation, Lahey Clinic, Burlington, MA
*Purpose: Transplantation of hepatitis C (HCV) positive organs into HCV negative recipients raises concerns regarding potential for infections unresponsive to DAAs. In September 2018, we…2020 American Transplant Congress
Natural History of Tacrolimus Intrapatient Variability During the First Post-Transplant Year
The Ohio State University Wexner Medical Center, Columbus, OH
*Purpose: High tacrolimus intrapatient variability (IPV) is associated with inferior outcomes in solid organ transplantation. Many evaluations of IPV empirically exclude the early post-transplant period…2020 American Transplant Congress
Pre-Transplant Pharmacogenetics Identifies CYP3A4 and CYP3A5 Heterogeneity among Caucasian Kidney Transplant Recipients
*Purpose: Tacrolimus has always been dosed based on therapeutic drug monitoring, however pharmacogenomics is becoming increasingly more utilized in the era of precision based medicine…
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