ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Pancreas Transplants in Asian Recipients

    A. Gruessner, C. Gruessner, S. Saggi, J. Renz

    SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Over the years, a change in patients receiving a pancreas transplant could be observed. While in the beginning the standard pancreas transplant recipient was…
  • 2020 American Transplant Congress

    Association between Sarcopenia and Nutritional Factors in Kidney Transplant Recipients

    A. Kosoku1, J. Uchida1, T. Ishihara2, T. Iwai1, H. Shimada1, K. Kabei1, S. Nishide1, T. Naganuma1, T. Nakatani1

    1Urology, Osaka City University Graduate School of Medicine, Osaka, Japan, 2Innovative and Clinical Research Promotion Center, Gifu University Hospital, Gihu, Japan

    *Purpose: Malnutrition is an important risk factor for the development of sarcopenia. Several methods are used for the assessment of nutritional status including serum albumin…
  • 2020 American Transplant Congress

    Donor-Derived Cell-Free DNA Kinetics in Stable Kidney Transplant Patients Are Related to Donor/Recipient Variables

    S. Anand, L. Dong, S. Dow, M. Fife, J. Krong, D. Morris, T. Srinivas

    Intermountain Medical Center, Murray, UT

    *Purpose: Donor-derived cell free DNA (dd-cfDNA) is increasingly used to monitor for allograft rejection. The relationship of dd-cfDNA to donor and recipient variables in not…
  • 2020 American Transplant Congress

    Accelerated Decline in Glomerular Density: An Unrecognized Pathologic Process after Kidney Transplantation

    A. Denic, B. H. Smith, W. D. Park, M. V. Luhman, M. P. Alexander, A. D. Rule, M. D. Stegall

    Mayo Clinic, Rochester, Rochester, MN

    *Purpose: Studies in healthy adults have shown that glomerular density slowly declines with older age (-0.5% per decade), and globally sclerotic glomeruli (GSG) slowly increase…
  • 2020 American Transplant Congress

    Immunohistochemical and Molecular Detection of NK Cells in Kidney Allografts with Antibody Mediated Rejection

    E. Farkash, J. Barnes, S. Anand

    Pathology, University of Michigan, Ann Arbor, MI

    *Purpose: Molecular signatures specific to Natural Killer (NK) cells are closely associated with antibody mediated rejection (AMR) in transplant biopsies. We have developed an immunohistochemical…
  • 2020 American Transplant Congress

    Two Pilot Studies Exploring the Diagnostic and Predictive Potential of Serum LAG3 and FGL1 in Kidney Transplant Recipients

    Y. Li1, L. Yan1, Y. Li1, C. Yang1, Z. Wan1, Y. An1, Y. Bai1, L. Wang1, Y. Shi2

    1Department of Laboratory Medicine, West China Hospital, Chengdu, China, 2Department of Nephrology, West China Hospital, Chengdu, China

    *Purpose: Lymphocyte activation gene 3 (LAG3), an immune checkpoint, plays an important role in the negative regulation of immune response and the induction of immune…
  • 2020 American Transplant Congress

    Immunosurveillance with Donor Derived Cellular Free DNA Assay Plus Donor Specific Antibody, an Alternative to Renal Allograft Biopsy

    S. Machado, G. Agarwal, F. Ahmed, B. Julian, R. Mannon, S. Mehta, V. Kumar, S. Ong, S. Thaduri, G. Towns, C. Kew

    Transplant Nephrology, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Surveillance allograft biopsies (SVAB) are used by many centers to identify subclinical immunologic injury. SVAB entails bleeding risks. Non-invasive modalities such as donor-derived cell-free…
  • 2020 American Transplant Congress

    Mass Cytometry-Based Immunoprofiling as a Tool to Predict Rejection in a Large Cohort of Pediatric Transplant Recipients

    M. Rao1, J. T. Harden2, M. Lapasaran2, C. O. Esquivel3, O. M. Martinez2, S. M. Krams2

    1Pediatrics, Stanford University, Palo Alto, CA, 2Stanford University School of Medicine, Stanford, CA, 3Surgery and Pediatrics, Stanford University School of Medicine, Stanford, CA

    *Purpose: Rejection remains a serious problem in the pediatric transplant population. Early detection remains a challenge; furthermore, the changes in immune makeup which accompany rejection…
  • 2020 American Transplant Congress

    Single Center Experience with Allograft Pancreatectomy

    V. Gurram, A. Farney, J. Rogers, G. Orlando, C. Jay, R. Stratta, D. Harriman

    Abdominal Transplant Surgery, Wake Forest Baptist Health, Winston Salem, NC

    *Purpose: Limited data on indications for and outcomes following allograft pancreatectomy (AP) exist. The purpose of this study was to analyze our single center experience…
  • 2020 American Transplant Congress

    The Histological Picture of Indication Biopsies in the First Days after Renal Transplantation

    E. Van Loon, M. Coemans, A. Senev, D. Kuypers, M. Emonds, M. Naesens

    Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium

    *Purpose: In preclinical studies, ischemia reperfusion injury and older donor age are associated with renal inflammation in the early phase after transplantation. In human kidney…
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