Abstracts Archive - Page 438 of 1683 - ATC Abstracts

2020 American Transplant Congress
The Pro-Inflammatory Profile of Alcoholic Patients Increases Risk for Ischemia-Reperfusion Injury During Orthotopic Liver Transplantation
A. Q. Terry¹, R. A. Sosa¹, M. Rossetti¹, F. Li¹, J. Nevarez-Mejia¹, B. V. Naini¹, F. M. Kaldas², V. M. Groysberg¹, S. M. Younan², R. W. Busuttil², D. W. Gjertson¹, J. W. Kupiec-Weglinski³, E. F. Reed¹
¹Department of Pathology and Laboratory Medicine, UCLA, Los Angeles, CA, ²Department of Surgery, UCLA, Los Angeles, CA, ³Departments of Pathology and Laboratory Medicine and Surgery, UCLA, Los Angeles, CA
*Purpose: Ischemia-reperfusion injury (IRI) elicits cellular damage which triggers a pro-inflammatory immune response that can lower allograft survival in orthotopic liver transplant (OLT) patients. In…
2020 American Transplant Congress
Normothermic Ex Vivo Perfusion of Marginal Liver Grafts Rapidly Stimulates Release of Graft-Derived Exosomes and Markedly Decreases the Inflammatory Pathways Induced at Early Times after Transplant Reperfusion
K. E. Brown¹, K. S. Keslar¹, D. Margeta¹, Q. Liu², A. Simioni², L. Del Angel Diaz², W. M. Baldwin¹, R. L. Fairchild¹, C. Quintini²
¹Lerner Research Institute, Cleveland Clinic, Cleveland, OH, ²Transplant Center, Cleveland Clinic, Cleveland, OH
*Purpose: Normothermic ex vivo machine perfusion of liver grafts (EVLP) is emerging as a superior preservation technology to cold storage. Normothermic EVLP transforms a metabolically…
2020 American Transplant Congress
Public Health Insurance is Associated with Reduced Access to Living Donor Liver Transplantation and Increased Liver Transplant Waiting List Mortality: An Analysis of the SRTR
R. Hogen¹, M. Aljehani², J. Lee³, L. Sher¹, Y. Genyk¹, J. Emamaullee¹
¹Surgery, Division of Hepatobiliary and Abdominal Organ Transplant Surgery, University of Southern California, Los Angeles, CA, ²Surgery, University of Southern California, Los Angeles, CA, ³Lawrence J. Ellison Institute for Transformative Medicine, University of Southern California, Los Angeles, CA
*Purpose: Living donor liver transplantation (LDLT) is associated with improved survival and lower hospital costs, but it continues to makes up less than 5% of…
2020 American Transplant Congress
Developing a Patient Specific Search of Heart Transplant Programs: Feedback from Heart Transplant Candidates and Recipients
W. T. McKinney¹, M. J. Bruin², C. R. Schaffhausen¹, S. Chu², J. Synder³, C. M. Martin⁴, T. Alexy⁴, B. L. Kasiske⁵, A. K. Israni¹
¹Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, ²College of Design, University of Minnesota, Minneapolis, MN, ³Hennepin Healthcare Research Institute, Minneapolis, MN, ⁴Cardiology Division, University of Minnesota Department of Medicine, Minneapolis, MN, ⁵Department of Medicine, Hennepin Healthcare, Minneapolis, MN
*Purpose: Patients seeking a heart transplant must contemplate numerous factors when making decisions regarding their care. Waitlist acceptance criteria, donor acceptance practices and outcomes often…
2020 American Transplant Congress
The Scenario of Delayed Graft Function in Brazil
T. V. Sandes-Freitas¹, M. Mazzali², R. Manfro³, H. Tedesco-Silva⁴, L. Andrade⁵, V. Garcia⁶, E. Davi-Neto⁷, R. Esmeraldo⁸, C. Oliveira⁹, E. Lasmar¹⁰, R. Madeira¹¹, G. Ferreira¹², G. Meira¹³, F. Cavalcanti¹⁴, A. Bignelli¹⁵, D. Carvalho¹⁶, D. Pedroso¹⁷, L. Deboni¹⁸, A. Silva e Filho¹⁹, A. Vicari³, M. Sousa², .. on behalf of 'DGF multicêntrico' group²⁰
¹Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil, ²HC/UNICAMP, Campinas, Brazil, ³HCPA/UFRGS, Porto Alegre, Brazil, ⁴Hospital do Rim, São Paulo, Brazil, ⁵HC-Botucatu/UNESP, Botucatu, Brazil, ⁶Santa Casa de Porto Alegre, Porto Alegre, Brazil, ⁷HC/FMUSP, São Paulo, Brazil, ⁸H. Geral de Fortaleza, Fortaleza, Brazil, ⁹HUWC/UFC, Fortaleza, Brazil, ¹⁰H. Universitário São José, Belo Horizonte, Brazil, ¹¹H. Felício Rocho, Belo Horizonte, Brazil, ¹²Santa Casa de Juiz de Fora, Juiz de Fora, Brazil, ¹³Santa Casa de Montes Claros, Montes Claros, Brazil, ¹⁴Real Hospital Português, Recife, Brazil, ¹⁵H. Universitário Cajuru, Curitiba, Brazil, ¹⁶H. São Francisco na Providencia de Deus, Rio de Janeiro, Brazil, ¹⁷H. Santa Isabel, Blumenau, Brazil, ¹⁸H. Municipal São José, Joinville, Brazil, ¹⁹H. Israelita Albert Einstein, São Paulo, Brazil, ²⁰ABTO, São Paulo, Brazil
*Purpose: Unicenter Brazilian studies reported high incidences (50-70%) of delayed graft function (DGF). This is a multicenter Brazilian study aimed to evaluate the incidence, the…
2020 American Transplant Congress
Accomplishment of Ischemia-Free Kidney Transplantation Using Normothermic Machine Perfusion
G. Chen, X. He, C. Wang, X. Yuan, M. Han, Z. Guo
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
*Purpose: Ischemia-reperfusion injury (IRI) has been considered an inevitable event in organ transplantation since the first successful kidney transplant was performed in 1954. To avoid…
2020 American Transplant Congress
The Impact of Deceased Donor Maintenance on the Incidence of Delayed Kidney Allograft Function
S. Costa¹, F. Barroso¹, C. Oliveira¹, E. Daher¹, P. Fernandes¹, L. Andrade², R. Esmeraldo³, T. Sandes-Freitas¹
¹Universidade Federal do Ceará, Fortaleza, Brazil, ²Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brazil, ³Hospital Geral de Fortaleza, Fortaleza, Brazil
*Purpose: To evaluate the risk factors for delayed graft function (DGF) in a Brazilian cohort with high DGF incidence, focusing on variables reflecting donor maintenance.*Methods:…
2020 American Transplant Congress
Association of Perfusion Characteristics and Post-Transplant Liver Function in Ischemia-Free Liver Transplantation
Z. Zhang, Y. Tang, Q. Zhao, Z. Guo, X. He
The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: It has been showed that normothermic machine perfusion (NMP), a novel preservation method, is able to assess and resuscitate liver grafts with risk factors.…
2020 American Transplant Congress
Sodium Zirconium Cyclosilicate Use in Solid Organ Transplant Recipients and its Effect on Potassium and Immunosuppression
R. Winstead, M. Demehin, I. Yakubu, C. Song, A. Brown, M. Levy, L. Kamal, G. Gupta
VCU Health, Richmond, VA
*Purpose: Transplant recipients often suffer from hyperkalemia which can limit pharmacotherapy. The cause of hyperkalemia is often multifactorial including kidney dysfunction, calcineurin inhibitor use, and…
2020 American Transplant Congress
Ex Vivo Pumping Through an OPO’s Eyes
A. L. Friedman, E. Marquez
LiveOnNY, New York, NY
*Purpose: A single, large organ procurement organization (OPO) sought to document the use of extra-renal ex vivo pumping in the management of the deceased donor…