Abstracts Archive - Page 431 of 1683 - ATC Abstracts

2020 American Transplant Congress
The Pro-Inflammatory Profile of Alcoholic Patients Increases Risk for Ischemia-Reperfusion Injury During Orthotopic Liver Transplantation
A. Q. Terry¹, R. A. Sosa¹, M. Rossetti¹, F. Li¹, J. Nevarez-Mejia¹, B. V. Naini¹, F. M. Kaldas², V. M. Groysberg¹, S. M. Younan², R. W. Busuttil², D. W. Gjertson¹, J. W. Kupiec-Weglinski³, E. F. Reed¹
¹Department of Pathology and Laboratory Medicine, UCLA, Los Angeles, CA, ²Department of Surgery, UCLA, Los Angeles, CA, ³Departments of Pathology and Laboratory Medicine and Surgery, UCLA, Los Angeles, CA
*Purpose: Ischemia-reperfusion injury (IRI) elicits cellular damage which triggers a pro-inflammatory immune response that can lower allograft survival in orthotopic liver transplant (OLT) patients. In…
2020 American Transplant Congress
Association between Education and Waitlist Mortality, Access to Transplant, and Post-Transplant Survival among Patients with Alcohol-Associated Liver Disease
A. T. Strauss, J. Motter, D. Segev, A. Massie, T. Purnell, J. Hamilton, A. Gurakar, A. Cameron, J. Garonzik-Wang
Johns Hopkins University, Baltimore, MD
*Purpose: Alcohol-associated liver disease (ALD) is the leading indication for liver transplant (LT) and these patients have been shown to have worse outcomes compared to…
2020 American Transplant Congress
The Scenario of Delayed Graft Function in Brazil
T. V. Sandes-Freitas¹, M. Mazzali², R. Manfro³, H. Tedesco-Silva⁴, L. Andrade⁵, V. Garcia⁶, E. Davi-Neto⁷, R. Esmeraldo⁸, C. Oliveira⁹, E. Lasmar¹⁰, R. Madeira¹¹, G. Ferreira¹², G. Meira¹³, F. Cavalcanti¹⁴, A. Bignelli¹⁵, D. Carvalho¹⁶, D. Pedroso¹⁷, L. Deboni¹⁸, A. Silva e Filho¹⁹, A. Vicari³, M. Sousa², .. on behalf of 'DGF multicêntrico' group²⁰
¹Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil, ²HC/UNICAMP, Campinas, Brazil, ³HCPA/UFRGS, Porto Alegre, Brazil, ⁴Hospital do Rim, São Paulo, Brazil, ⁵HC-Botucatu/UNESP, Botucatu, Brazil, ⁶Santa Casa de Porto Alegre, Porto Alegre, Brazil, ⁷HC/FMUSP, São Paulo, Brazil, ⁸H. Geral de Fortaleza, Fortaleza, Brazil, ⁹HUWC/UFC, Fortaleza, Brazil, ¹⁰H. Universitário São José, Belo Horizonte, Brazil, ¹¹H. Felício Rocho, Belo Horizonte, Brazil, ¹²Santa Casa de Juiz de Fora, Juiz de Fora, Brazil, ¹³Santa Casa de Montes Claros, Montes Claros, Brazil, ¹⁴Real Hospital Português, Recife, Brazil, ¹⁵H. Universitário Cajuru, Curitiba, Brazil, ¹⁶H. São Francisco na Providencia de Deus, Rio de Janeiro, Brazil, ¹⁷H. Santa Isabel, Blumenau, Brazil, ¹⁸H. Municipal São José, Joinville, Brazil, ¹⁹H. Israelita Albert Einstein, São Paulo, Brazil, ²⁰ABTO, São Paulo, Brazil
*Purpose: Unicenter Brazilian studies reported high incidences (50-70%) of delayed graft function (DGF). This is a multicenter Brazilian study aimed to evaluate the incidence, the…
2020 American Transplant Congress
The Histological Picture of Indication Biopsies in the First Days after Renal Transplantation
E. Van Loon, M. Coemans, A. Senev, D. Kuypers, M. Emonds, M. Naesens
Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
*Purpose: In preclinical studies, ischemia reperfusion injury and older donor age are associated with renal inflammation in the early phase after transplantation. In human kidney…
2020 American Transplant Congress
Ex Vivo Pumping Through an OPO’s Eyes
A. L. Friedman, E. Marquez
LiveOnNY, New York, NY
*Purpose: A single, large organ procurement organization (OPO) sought to document the use of extra-renal ex vivo pumping in the management of the deceased donor…
2020 American Transplant Congress
Association of Perfusion Characteristics and Post-Transplant Liver Function in Ischemia-Free Liver Transplantation
Z. Zhang, Y. Tang, Q. Zhao, Z. Guo, X. He
The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: It has been showed that normothermic machine perfusion (NMP), a novel preservation method, is able to assess and resuscitate liver grafts with risk factors.…
2020 American Transplant Congress
Public Health Insurance is Associated with Reduced Access to Living Donor Liver Transplantation and Increased Liver Transplant Waiting List Mortality: An Analysis of the SRTR
R. Hogen¹, M. Aljehani², J. Lee³, L. Sher¹, Y. Genyk¹, J. Emamaullee¹
¹Surgery, Division of Hepatobiliary and Abdominal Organ Transplant Surgery, University of Southern California, Los Angeles, CA, ²Surgery, University of Southern California, Los Angeles, CA, ³Lawrence J. Ellison Institute for Transformative Medicine, University of Southern California, Los Angeles, CA
*Purpose: Living donor liver transplantation (LDLT) is associated with improved survival and lower hospital costs, but it continues to makes up less than 5% of…
2020 American Transplant Congress
Natural History of Tacrolimus Intrapatient Variability During the First Post-Transplant Year
A. D. Leino, J. L. Rodgers, K. M. Abuls
The Ohio State University Wexner Medical Center, Columbus, OH
*Purpose: High tacrolimus intrapatient variability (IPV) is associated with inferior outcomes in solid organ transplantation. Many evaluations of IPV empirically exclude the early post-transplant period…
2020 American Transplant Congress
Pre-Transplant Pharmacogenetics Identifies CYP3A4 and CYP3A5 Heterogeneity among Caucasian Kidney Transplant Recipients
N. Oliver¹, L. Lindberg¹, S. LeCorchick¹, D. Morris¹, S. Anand¹, T. Srinivas²
¹Intermountain Medical Center, Murray, UT, ²University Hospitals Cleveland Medical Center, Cleveland, OH
*Purpose: Tacrolimus has always been dosed based on therapeutic drug monitoring, however pharmacogenomics is becoming increasingly more utilized in the era of precision based medicine…
2020 American Transplant Congress
Sodium Zirconium Cyclosilicate Use in Solid Organ Transplant Recipients and its Effect on Potassium and Immunosuppression
R. Winstead, M. Demehin, I. Yakubu, C. Song, A. Brown, M. Levy, L. Kamal, G. Gupta
VCU Health, Richmond, VA
*Purpose: Transplant recipients often suffer from hyperkalemia which can limit pharmacotherapy. The cause of hyperkalemia is often multifactorial including kidney dysfunction, calcineurin inhibitor use, and…