ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Management of Pancreatic Cancer after Liver Transplantation: A 27-Year Single-Center Experience

    I. A. Ziogas, M. A. Rauf, L. K. Matsuoka, M. I. Montenovo, M. Izzy, S. P. Alexopoulos

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: The occurrence of de novo cancer after liver transplant (LT) is a leading cause of post-LT mortality and can be partially attributed to the…
  • 2020 American Transplant Congress

    Normothermic Ex Vivo Perfusion of Marginal Liver Grafts Rapidly Stimulates Release of Graft-Derived Exosomes and Markedly Decreases the Inflammatory Pathways Induced at Early Times after Transplant Reperfusion

    K. E. Brown1, K. S. Keslar1, D. Margeta1, Q. Liu2, A. Simioni2, L. Del Angel Diaz2, W. M. Baldwin1, R. L. Fairchild1, C. Quintini2

    1Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 2Transplant Center, Cleveland Clinic, Cleveland, OH

    *Purpose: Normothermic ex vivo machine perfusion of liver grafts (EVLP) is emerging as a superior preservation technology to cold storage. Normothermic EVLP transforms a metabolically…
  • 2020 American Transplant Congress

    The Association between Donor Hypothermia and Allograft Outcomes in Liver and Kidney Transplantation

    S. Karhadkar, B. Kaplunov, A. Di Carlo

    Temple University School of Medicine, Philadelphia, PA

    *Purpose: Traumatic brain injury patients benefit from mild to moderate hypothermia (32-35 °C); and in patients with cardiac arrest, stroke, and asphyxia, hypothermia is and…
  • 2020 American Transplant Congress

    The Impact of Deceased Donor Maintenance on the Incidence of Delayed Kidney Allograft Function

    S. Costa1, F. Barroso1, C. Oliveira1, E. Daher1, P. Fernandes1, L. Andrade2, R. Esmeraldo3, T. Sandes-Freitas1

    1Universidade Federal do Ceará, Fortaleza, Brazil, 2Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brazil, 3Hospital Geral de Fortaleza, Fortaleza, Brazil

    *Purpose: To evaluate the risk factors for delayed graft function (DGF) in a Brazilian cohort with high DGF incidence, focusing on variables reflecting donor maintenance.*Methods:…
  • 2020 American Transplant Congress

    Successful Transplantation of Murine Hearts Preserved 24h Under Subzero Ischemia Using Novel Bio-Inspired Next Generation Cryoprotectants

    B. Oh1, A. Callegari2, M. Kline2, A. Childs2, M. Iglesias Lozano1, G. Brandacher1, X. Wei2

    1Department of Plastic and Reconstructive Surgery, Vascularized Composite Allotransplantation (VCA), Johns Hopkins University School of Medicine, Baltimore, MD, 2X-Therma Inc., Richmond, CA

    *Purpose: Extension of the organ ischemia window is of paramount importance to prolong viability of transplantable organs and to improve overall outcomes. Transport using a…
  • 2020 American Transplant Congress

    Association of Perfusion Characteristics and Post-Transplant Liver Function in Ischemia-Free Liver Transplantation

    Z. Zhang, Y. Tang, Q. Zhao, Z. Guo, X. He

    The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    *Purpose: It has been showed that normothermic machine perfusion (NMP), a novel preservation method, is able to assess and resuscitate liver grafts with risk factors.…
  • 2020 American Transplant Congress

    The Scenario of Delayed Graft Function in Brazil

    T. V. Sandes-Freitas1, M. Mazzali2, R. Manfro3, H. Tedesco-Silva4, L. Andrade5, V. Garcia6, E. Davi-Neto7, R. Esmeraldo8, C. Oliveira9, E. Lasmar10, R. Madeira11, G. Ferreira12, G. Meira13, F. Cavalcanti14, A. Bignelli15, D. Carvalho16, D. Pedroso17, L. Deboni18, A. Silva e Filho19, A. Vicari3, M. Sousa2, .. on behalf of 'DGF multicêntrico' group20

    1Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil, 2HC/UNICAMP, Campinas, Brazil, 3HCPA/UFRGS, Porto Alegre, Brazil, 4Hospital do Rim, São Paulo, Brazil, 5HC-Botucatu/UNESP, Botucatu, Brazil, 6Santa Casa de Porto Alegre, Porto Alegre, Brazil, 7HC/FMUSP, São Paulo, Brazil, 8H. Geral de Fortaleza, Fortaleza, Brazil, 9HUWC/UFC, Fortaleza, Brazil, 10H. Universitário São José, Belo Horizonte, Brazil, 11H. Felício Rocho, Belo Horizonte, Brazil, 12Santa Casa de Juiz de Fora, Juiz de Fora, Brazil, 13Santa Casa de Montes Claros, Montes Claros, Brazil, 14Real Hospital Português, Recife, Brazil, 15H. Universitário Cajuru, Curitiba, Brazil, 16H. São Francisco na Providencia de Deus, Rio de Janeiro, Brazil, 17H. Santa Isabel, Blumenau, Brazil, 18H. Municipal São José, Joinville, Brazil, 19H. Israelita Albert Einstein, São Paulo, Brazil, 20ABTO, São Paulo, Brazil

    *Purpose: Unicenter Brazilian studies reported high incidences (50-70%) of delayed graft function (DGF). This is a multicenter Brazilian study aimed to evaluate the incidence, the…
  • 2020 American Transplant Congress

    Accomplishment of Ischemia-Free Kidney Transplantation Using Normothermic Machine Perfusion

    G. Chen, X. He, C. Wang, X. Yuan, M. Han, Z. Guo

    Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

    *Purpose: Ischemia-reperfusion injury (IRI) has been considered an inevitable event in organ transplantation since the first successful kidney transplant was performed in 1954. To avoid…
  • 2020 American Transplant Congress

    Association between Education and Waitlist Mortality, Access to Transplant, and Post-Transplant Survival among Patients with Alcohol-Associated Liver Disease

    A. T. Strauss, J. Motter, D. Segev, A. Massie, T. Purnell, J. Hamilton, A. Gurakar, A. Cameron, J. Garonzik-Wang

    Johns Hopkins University, Baltimore, MD

    *Purpose: Alcohol-associated liver disease (ALD) is the leading indication for liver transplant (LT) and these patients have been shown to have worse outcomes compared to…
  • 2020 American Transplant Congress

    Noninvasive Genotyping of Donor’s HLA in Kidney Transplant Patients by Target Capture Sequencing

    T. Jiang, L. Shu, F. Liu, H. Liu, J. Ge

    AlloDx, Shanghai; Suzhou, China

    *Purpose: Antibody-mediated rejection (ABMR) is the major cause of kidney transplant failure, which requires donor-specific antibodies (DSA) for a definitive diagnosis based on Banff 2013.…
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