Abstracts Archive - Page 43 of 1683 - ATC Abstracts

2022 American Transplant Congress
Donor and Recipient Age Matching for Kidney Transplantation: A Machine Learning Approach
J. Kim, J. Ahn, A. Massie, D. Segev, S. Bae
Johns Hopkins, Baltimore, MD
*Purpose: Under the concept of ‘longevity matching,’ the Kidney Allocation System favors matching younger deceased donors with younger kidney transplant (KT) candidates. However, it remains…
2022 American Transplant Congress
Additional Dose of SARS-CoV-2 Vaccine Increases Neutralization Capacity in Solid Organ Transplant Recipients
Y. Yoo¹, J. Husson², T. Iraguha³, S. Niederhaus⁴, X. Wen⁵, A. Crane⁵, A. Carrier⁵, J. Avruch⁵, A. Ahuja⁶, M. Mathew⁷, S. Dahiya⁸, A. P. Rapoport⁸, D. Atanackovic⁸, K. K. Saharia²
¹Inst of Human Virology, Baltimore, MD, ²Div of Infect Diseases, Univ of Maryland School of Med. and Inst of Human Virology, Baltimore, MD, ³Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD, ⁴Dept of Surgery, Univ of Maryland School of Med., Baltimore, MD, ⁵Dept of Surgery, Univ of Maryland Med. Center, Baltimore, MD, ⁶Dept of Medicine, Univ of Maryland Med. Center, Baltimore, MD, ⁷Div of Infect. Diseases, Univ of Maryland Med. Center, Baltimore, MD, ⁸Dept of Medicine, Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD
*Purpose: Solid organ transplant recipients (SOTR) develop weak antibody responses after SARS-CoV-2 vaccination. Published data on neutralizing activity of plasma, a better measure of protection,…
2022 American Transplant Congress
Impact of Donor-to-Recipient Body Surface Area Ratio on Graft Survival and Mortality Following Deceased Donor Liver Transplants
S. Radomski, L. Zeiser, A. Massie, S. Ottmann, D. Segev, E. King
Surgery, Johns Hopkins University, Baltimore, MD
*Purpose: The impact of size mismatch on graft survival in living donor liver transplant is well established but is not a common concern in deceased…
2022 American Transplant Congress
Leveraging Single-Cell Signatures in Kidney Transplant Biopsies Uncovers Immunological Heterogeneity Within Rejection Phenotypes
J. Callemeyn¹, B. Lamarthée¹, P. Koshy², T. Debyser³, E. Van Loon¹, A. Franken⁴, T. Van Brussel⁴, I. Arijs⁴, D. Lambrechts⁴, M. Rabant⁵, A. Senev¹, T. Vaulet⁶, C. Tinel¹, M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²Department of Morphology and Molecular Pathology, University Hospitals Leuven, Leuven, Belgium, ³Faculty of Medicine, KU Leuven, Leuven, Belgium, ⁴Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium, ⁵Necker-Enfants Malades Institute, Institut national de la santé et de la recherche médicale (Inserm), Université de Paris, Paris, France, ⁶ESAT Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium
*Purpose: Rejection of the kidney allograft is hallmarked by the accumulation of inflammatory cells within the renal architecture, leading to microvascular or tubulointerstitial inflammation. However,…
2022 American Transplant Congress
Axl and MerTK Regulate the Activation of Liver Ischemia Reperfusion Injury by Upregulating Il-13 in Kupffer Cells
J. Zhang¹, M. Ni¹, H. Zhang¹, R. Busuttil¹, J. Kupiec-Weglinski¹, X. Wang², J. Jin³, Y. Zhai¹
¹Dumont-UCLA Transplant Center, Los Angeles, CA, ²The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, ³Guilin Medical University, Guilin, China
*Purpose: Ischemia reperfusion injury (IRI) remains an unresolved clinical problem. A sterile inflammatory response drives the disease pathogenesis. Although mechanisms of liver innate immune activation…
2022 American Transplant Congress
Bone Fractures Are Not Increased in Older Prior Living Kidney Donors
H. Amer¹, H. Maradit Kremers¹, D. Larson¹, I. Zaniletti¹, W. K. Kremers¹, A. Matas², B. Kasiske³, S. Khosla¹, R. Kumar¹
¹Mayo Clinic, Rochester, MN, ²University of Minnesota, Minneapolis, MN, ³Hennepin County Medical Center, Minneapolis, MN
*Purpose: Living kidney donors were shown to have derangements of bone biomarkers resembling those occurring in early chronic kidney disease within 36 months of donation.…
2022 American Transplant Congress
Renal Transplantation and Statins Effects on Dyslipidemia in Renal Transplant Recipients
Z. Arabi, A. Alghamdi, A. Alnasrullah, A. R. Altheaby, M. Tawhari, N. Alnazari
KAMC, Riyadh, Saudi Arabia
*Purpose: to review the effect of renal transplantation and adding of statins on dyslipidemia in renal transplant recipients.*Methods: A single center experience retrospective study of…
2022 American Transplant Congress
Time-Dependent Blood Eosinophilia Count Increases the Risk of Kidney Allograft Rejection
L. Colas¹, L. Bui², C. Kerleau³, M. Lemdani⁴, K. Autain-Renaudin⁵, A. Magnan⁶, M. Giral³, S. Brouard¹
¹CRT2I, Université de Nantes, Nantes, France, ²Service de Néphrologie, Centre Hospitalier de Mouscron, Mouscron, Belgium, ³Service de Néphrologie et Immunologie Clinique, CHU de Nantes, Nantes, France, ⁴Département de Biomathématiques, Université de Lilles, Lilles, France, ⁵Service d'Anatomie et Cytologie Pathologique, CHU de Nantes, Nantes, France, ⁶INRAe UMR 0892, Université de Versailles Saint-Quentin Paris-Saclay, Paris, France
*Purpose: There is growing evidence that type 2 immune effectors (immunoglobulin E, eosinophils, mast cells/basophils) play a role in autoimmune disorders and solid organ transplantation.…
2022 American Transplant Congress
Access to Pediatric Kidney Transplant: The Impact of Mental Health Diagnoses and Social Determinants of Health
E. Blanchette¹, E. Benz¹, J. Armendariz¹, K. McKinnon¹, M. Chandran², E. S. Christofferson¹, M. Bisek¹, M. Bock¹
¹Children's Hospital Colorado, Aurora, CO, ²Pharmacy, UNC Hospitals, Chapel Hill, NC
*Purpose: Limited and delayed access to kidney transplant (KT) has been associated with characteristics of adult KT candidates, including mental health (MH) diagnoses, negative social…
2022 American Transplant Congress
What If Only Days After Dialysis Counted Towards Kidney Candidates’ Qualified Waiting Times?
G. R. Vece, K. Lindblad, M. Stuart, B. Carrico, D. Stewart, D. Klassen, S. Diallo
Research, United Network for Organ Sharing, Richmond, VA
*Purpose: Current kidney policy allows patients who have not yet initiated dialysis to qualify for allocation priority based on the time since a recorded eGFR…