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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Patient-Reported Barriers to Living Kidney Donor Follow-Up

    B. Orandi, R. Reed, H. Qu, G. Owens, S. Brooks, C. Killian, V. Kumar, S. Sheikh, R. Cannon, C. Lewis, J. Locke

    University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Despite regulations mandating follow-up laboratory testing for living kidney donors, less than half of transplant centers are in compliance. We sought to understand barriers…
  • 2022 American Transplant Congress

    Can We Predict Progression of Potential Donation After Cardiac Death Donors (DCD) Using DonorNet?

    Y. Bababekov1, A. Yule1, H. Moore1, R. Choudhury2, C. Hertert3, T. Pshak4, T. Nydam5, B. Kaplan1, E. Pomfret1, J. Pomposelli5

    1Transplant Surgery, University of Colorado, Aurora, CO, 2University of Colorado Hospital, Denver, CO, 3Donor Alliance, Denver, CO, 4University of Colorado, Denver, CO, 5University of Colorado, Aurora, CO

    *Purpose: DCD utilization of livers is limited by unpredictability of progression, perceived worse outcome, and costs related to deployment of resources. We aimed to predict…
  • 2022 American Transplant Congress

    A Model for Medical Device Innovation in Transplantation: Using the Biodesign Process to Address the Impact of Warm Ischemic Injury

    K. Hansen1, J. Wall2

    1University of California San Francisco, San Francisco, CA, 2Stanford University, Palo Alto, CA

    *Purpose: The impact of warming during second warm-ischemia (anastomosis) of kidney transplantation has been increasingly recognized in the literature. The outsized effect on delayed graft…
  • 2022 American Transplant Congress

    Additional Dose of SARS-CoV-2 Vaccine Increases Neutralization Capacity in Solid Organ Transplant Recipients

    Y. Yoo1, J. Husson2, T. Iraguha3, S. Niederhaus4, X. Wen5, A. Crane5, A. Carrier5, J. Avruch5, A. Ahuja6, M. Mathew7, S. Dahiya8, A. P. Rapoport8, D. Atanackovic8, K. K. Saharia2

    1Inst of Human Virology, Baltimore, MD, 2Div of Infect Diseases, Univ of Maryland School of Med. and Inst of Human Virology, Baltimore, MD, 3Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD, 4Dept of Surgery, Univ of Maryland School of Med., Baltimore, MD, 5Dept of Surgery, Univ of Maryland Med. Center, Baltimore, MD, 6Dept of Medicine, Univ of Maryland Med. Center, Baltimore, MD, 7Div of Infect. Diseases, Univ of Maryland Med. Center, Baltimore, MD, 8Dept of Medicine, Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD

    *Purpose: Solid organ transplant recipients (SOTR) develop weak antibody responses after SARS-CoV-2 vaccination. Published data on neutralizing activity of plasma, a better measure of protection,…
  • 2022 American Transplant Congress

    Bone Fractures Are Not Increased in Older Prior Living Kidney Donors

    H. Amer1, H. Maradit Kremers1, D. Larson1, I. Zaniletti1, W. K. Kremers1, A. Matas2, B. Kasiske3, S. Khosla1, R. Kumar1

    1Mayo Clinic, Rochester, MN, 2University of Minnesota, Minneapolis, MN, 3Hennepin County Medical Center, Minneapolis, MN

    *Purpose: Living kidney donors were shown to have derangements of bone biomarkers resembling those occurring in early chronic kidney disease within 36 months of donation.…
  • 2022 American Transplant Congress

    Pegloticase for Uncontrolled Gout in Kidney Transplant Recipients: Provisional Data Report of a Multicenter, Open-Label, Efficacy and Safety Study

    A. Abdellatif1, L. Zhao2, K. Cherny2, B. Marder2, J. D. Scandling3, K. Saag4

    1Division of Nephrology, Baylor College of Medicine, Houston, TX, 2Horizon Therapeutics PLC, Deerfield, IL, 3Division of Nephrology, Stanford School of Medicine, Stanford, CA, 4Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Gout in kidney transplant (KT) recipients can be severe and particularly challenging to manage. Pegloticase co-therapy with immunomodulators improved urate lowering therapy (ULT) response…
  • 2022 American Transplant Congress

    Characteristics and Outcomes of Anhepatic Patients Listed for Liver Retransplantation

    R. G. Kathawate1, T. Ibeabuchi2, P. Abt2, T. Bittermann2

    1University of Michigan, Ann Arbor, MI, 2University of Pennsylvania, Philadelphia, PA

    *Purpose: The frequency and outcomes of anhepatic patients listed for transplantation in the United States has not been previously described. The United Network for Organ…
  • 2022 American Transplant Congress

    Liver Transplantation for Primary Sclerosing Cholangitis (psc): Experience from the Last Three Decades

    J. Zhu1, D. Lim1, L. James1, E. Yoshida2, K. Peltekian1

    1Medicine, Dalhousie University, Halifax, NS, Canada, 2Medicine, University of British Columbia, Vancouver, BC, Canada

    *Purpose: In liver transplantation (LT) for PSC, pre-transplant colectomy may lower the risk of PSC recurrence (rPSC), and well-controlled or lack of IBD may protect…
  • 2022 American Transplant Congress

    Impact of Graft Type, Presence and Type of Inflammatory Bowel Disease on Outcomes Following Liver Transplantation for Primary Sclerosing Cholangitis

    S. Kumar1, S. Lin2, J. D. Schold3

    1Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, 2Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, 3Center for Populations Health Research, Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: In Primary sclerosing cholangitis (PSC), concerns exist regarding outcomes following donation after circulatory death (DCD) liver transplantation (LT) due to risk of ischemic cholangiopathy…
  • 2022 American Transplant Congress

    Superoxide in Cardiac Allografts from Donors After Circulatory Death

    M. Urban1, T. Bruett2, K. F. Duncan1, N. W. Markin3, M. M. Chacon3, M. C. Zimmerman4

    1Department of Surgery. Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE, 2College of Medicine. Department of Cellular and Integtrative Physiology., University of Nebraska Medical Center, Omaha, NE, 3Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, 4Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE

    *Purpose: Quality of cardiac allografts from donors after circulatory death (DCD) is adversely impacted by warm ischemia and subsequent reperfusion during organ resuscitation. Post-transplant myocardial…
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