ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Operative vs. Non-Operative Management of Hemorrhage in the Postoperative Kidney Transplant Patient

    R. Shaw1, T. Reavis1, V. Meruva2, F. Montz3, E. Rogers4, A. Kumar1, V. Bowers4, J. Buggs4

    1Morsani College of Medicine, University of South Florida, Tampa, FL, 2Lake Erie College of Osteopathic Medicine, Bradenton, FL, 3University of Tampa, Tampa, FL, 4Transplant Surgery, Tampa General Hospital, Tampa, FL

    *Purpose: Postoperative hemorrhage has been described at rates of 14 percent in kidney transplant (KT) literature. The preferred management of postoperative hemorrhage in this population…
  • 2020 American Transplant Congress

    Monitoring Inflammatory Cytokines in HLA-Sensitized Kidney Transplant Patients (HS KTx Pts) Desensitized with Clazakizumab (CLZ, Humanized Anti-IL-6 Monoclonal Antibody) Followed by Transplantation (Tx)

    S. Ge1, A. Petrosyan1, M. Chu1, N. Ammerman2, A. Vo2, X. Zhang3, S. C. Jordan2, M. Toyoda1

    1Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, 2Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, 3HLA Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: Chronic inflammation and HLA sensitization are burdens for end stage renal disease Pts awaiting for a KTx. IL-6 is a pro-inflammatory cytokine responsible for…
  • 2020 American Transplant Congress

    Renal Transplantation Into Urinary Diversions and Reconstructed Bladders

    J. J. Chong, R. H. Zakri, S. Khan, G. Koffman, N. Mamode, J. Olsburgh

    Guy's Hospital, London, United Kingdom

    *Purpose: Renal failure secondary to urological disorders can necessitate urinary diversion or reconstruction either pre or post-kidney transplant. Decision making regarding timing of diversion or…
  • 2020 American Transplant Congress

    Ex-Vivo Repair of Complex Hilar Renal Artery Aneurysms and Auto-Transplantation of Solidary Kidney

    K. Zhao1, A. Naji2

    1University Hospitals Cleveland Medical Center, Cleveland, OH, 2University of Pennsylvania, Philadelphia, PA

    *Purpose: We present a case of ex-vivo repair of complex renal hilar saccular aneurysm followed by auto-transplantation of the solitary kidney.*Methods: The patient was a…
  • 2020 American Transplant Congress

    The Potential Significance of ABO Genotyping for Donor Selection in Kidney Transplantation

    Y. Zhou1, W. Deng1, Y. Wang1, N. Cui1, Y. Wu1, J. Xu1, S. Fu1, L. Xiao1, H. Liu1, F. Xiong2, Y. Miao1

    1Department of Organ Trasplantation, Nanfang Hospital, Guangzhou, China, 2Southern Medical University, Guangzhou, China

    *Purpose: The ABO blood group system is clinically important in kidney transplantation, but ABO genotyping fails to attract sufficient attention in China. We identified one…
  • 2020 American Transplant Congress

    Effect of Hepatic Steatosis on Hepatic Ischemia-Reperfusion Induced Acute Kidney Injury in Mice

    T. Nikumbh1, N. Biswas2, A. Das2, C. K. Sen2, S. Kubal1

    1Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN, 2ICRME, Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Livers with mild to moderate steatosis have been used to expand the donor pool for transplantation. However, livers with steatosis have a propensity for…
  • 2020 American Transplant Congress

    Prevalence of Kidney Transplant-Associated Thrombotic Microangiopathy after ABO-Incompatible Kidney Transplantation

    Y. Kakuta1, M. Okumi1, T. Kanzawa1, K. Unagami2, H. Ishida2, K. Tanabe1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan, 2Organ Transplant Medicine, Tokyo Women's Medical University, Tokyo, Japan

    *Purpose: Thrombotic microangiopathy (TMA) is a dangerous disorder characterized by fragmented red blood cells, decreased platelet count, and organ failure due to thrombosis. We investigated…
  • 2020 American Transplant Congress

    Bone Marrow Plasma Cell Heterogeneity Drives Resistance of Proteasome Inhibitor Therapy

    C. M. Castro-Rojas1, S. Tremblay2, J. Driscoll3, K. Roskin4, R. R. Alloway3, E. Woodle2, D. A. Hildeman1

    1Immunobiology, Cincinnati Children's Hospital, Cincinnati, OH, 2Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, 3Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 4Biomedical Informatics, Cincinnati Children's Hospital, Cincinnati, OH

    *Purpose: Patients sensitized to HLA antigens by prior transplantation, pregnancy or blood transfusion may have markedly prolonged waiting times for transplant. Moreover, once transplanted, the…
  • 2020 American Transplant Congress

    Estimating Alloantibody Levels in Highly-Sensitized Renal Allograft Candidates Using Serial Dilutions

    C. Maguire1, A. R. Tambur1, C. Schinstock2, M. D. Stegall2

    1Northwestern University, Chicago, IL, 2Mayo Clinic, Rochester, MN

    *Purpose: Despite the new Kidney Allocation System and Kidney Paired Donation, renal allograft candidates with a >99.9% cPRA still have extremely low rates of transplantation…
  • 2020 American Transplant Congress

    Outcomes of Post-Transplant Desensitization in High Immunological Risk Deceased Donor Kidney Transplant Recipients

    D. Kumar, C. Song, L. Kamal, I. Moinuddin, M. Levy, C. Bhati, A. King, P. Kimball, G. Gupta

    Virginia Commonwealth University, Richmond, VA

    *Purpose: The kidney allocation system (KAS) was changed in 2015 to increase access to transplants for highly sensitized patients. However, recent data suggests that even…
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