ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Long Term Effect of Tacrolimus Conversion to Sirolimus with Prednisone-Free Regimen in Kidney Allograft Outcomes: A Dynamic Analysis of Graft Survival Using Joint Modeling

    S. H. Park1, B. Ho1, K. Guo1, L. Zhao2, V. Mas3, J. Leventhal4, L. Gallon1

    1Transplant Nephrology, Northwestern University, Chicago, IL, 2Preventive Medicine, Northwestern University, Chicago, IL, 3University of Tennesse, Memphis, TN, 4Transplant Surgery, Northwestern University, Chicago, IL

    *Purpose: Findings on long-term impacts of the mammalian target of rapamycin inhibitor inhibitors on kidney allograft are scarce and mixed. A joint modeling approach can…
  • 2020 American Transplant Congress

    Predictability of Eplet Mismatch to Acute Rejection in Low Level HLA Antigen Mismatched Kidney Transplantation: Analysis of Korean Organ Transplantation Registry (KOTRY) Data

    J. Jeong1, Y. Hong1, Y. Park2, I. Park3, J. Park4, D. Chae5, J. Yang6, C. Ahn5, B. G. Park7

    1Seoul National University Bundang Hospital, Seongnam, Korea, Republic of, 2Gachon University, Incheon, Korea, Republic of, 3Ajou University School of Medicine, Suwon, Korea, Republic of, 4Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, 5Seoul National University College of Medicine, Seoul, Korea, Republic of, 6Seoul National University Hospital, Seoul, Korea, Republic of, 7Korea University Guro Hospital, Seoul, Korea, Republic of

    *Purpose: Epitope matching has been shown to better predict allograft survival and development of de novo donor specific antibodies. In previous study, the number of…
  • 2020 American Transplant Congress

    A Mouse Model of Non-MHC Mismatches Recapitulates Chronic Allograft Dysfunction and I-IFTA

    V. Pavlov1, F. Garzon1, R. Haroon Al Rasheed2, K. Banu1, F. ElSalem1, L. Li1, E. Cody1, M. Planoutene1, N. Chun1, Z. Zhang1, J. Leventhal1, B. Murphy1, P. Heeger1, M. C. Menon1

    1Medicine, Mount Sinai School of Medicine, New York, NY, 2Pathology, Mount Sinai School of Medicine, New York, NY

    *Purpose: Fibrotic and atrophic changes or IF/TA is an important cause of graft loss. We reported that genome-wide donor-recipient non-HLA mismatches independently correlate with Banff…
  • 2020 American Transplant Congress

    Low Mycophenolic Acid Levels are Associated with More Inflammation on 1 Year Protocol Biopsies and Lower Graft Survival in Kidney Transplant Recipients

    J. Huskey, G. Mour, M. Ryan, S. Nair, M. Smith, R. Heilman

    Mayo Clinic Arizona, Phoenix, AZ

    *Purpose: Data is limited on the association of Mycophenolic Acid (MPA) concentration on protocol kidney transplant biopsies. Our aim is to compare clinical outcomes and…
  • 2020 American Transplant Congress

    Can Organ Donor Potential Be Determined from Death Certificates? A Case Report

    S. Gunderson, J. Kemink, C. Topp, W. Payne, T. Brown, B. Welsch

    LifeSource, Minneapolis, MN

    *Purpose: The 12/17/19 CMS proposed rule revises outcome measures for OPOs using CDC Multiple Cause of Death to determine donation potential defined as the number…
  • 2020 American Transplant Congress

    Type 3 Innate Lymphoid Cells Are Associated with a Successful Intestinal Transplant

    J. Kang1, K. Loh1, L. Belyayev1, S. Moturi1, M. Sadat1, K. Khan1, A. Duttargi1, Y. Gusev2, K. Bhuvaneshwar2, H. Ressom2, J. Hawksworth1, C. Matsumoto1, T. Fishbein1, A. Kroemer1

    1MedStar Georgetown Transplant Institute, Washington, DC, 2Georgetown University, Washington, DC

    *Purpose: Innate lymphoid cells (ILCs) play fundamental roles in mucosal barrier functionality and tissue homeostasis. We hypothesized that protective IL-22-producing NKp44+ILC3 subsets are reduced under…
  • 2020 American Transplant Congress

    Technology Access, Use, and Intent among Kidney Transplant Candidates Vulnerable to Health Disparities

    S. Smith1, M. Keller2, R. Seibert3, L. Kayler1

    1Transplant, Transplant and Kidney Care Regional Center of Excellence, Erie County Medical Center, Buffalo, NY, 2Transplant, University at Buffalo, State University of New York, Department of Community Health and Health Behavior, Buffalo, NY, 3Transplant, University at Buffalo, State University of New York, Department of Epidemiology and Environmental Health, Buffalo, NY

    *Purpose: Advances in eHealth have created opportunities to reach vulnerable populations, however, eHealth strategies could paradoxically increase health disparities if vulnerable individuals lack technology access…
  • 2020 American Transplant Congress

    Outcomes of Acute Allograft Rejection Treatment with R Anti-Thymocyte Globulin (r-ATG) One Year Post Kidney Transplant

    M. Yaqub, A. Riaz, D. Mishler, O. Adebiyi, T. Taber, A. Sharfuddin

    Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Acute allograft rejection is considered one of the major causes of renal allograft dysfunction. Despite maximal anti-rejection therapy grafts may not regain baseline function.…
  • 2020 American Transplant Congress

    Chronic Active T-Cell Mediated Rejection is Variably Responsive to Immunosuppressive Therapy

    V. Kung1, M. Haas1, M. Gillespie2, E. Huang2, R. Sandhu2

    1Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, 2Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: Chronic active T cell-mediated rejection (CACMR) is a newly described variant of kidney allograft rejection associated with long-term graft loss. A key histologic feature…
  • 2020 American Transplant Congress

    Anatomy of a Conversation: Assessing ESRD Patients’ Transplant-Related Communication

    H. M. Gardiner

    Social and Behavioral Sciences, Temple University, Philadelphia, PA

    *Purpose: Live Donor and Deceased Donor Kidney Transplantation (LDKT and DDKT) confer meaningful survival, and quality of life benefits to patients with End Stage Renal…
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