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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Longevity Matching for Living Donor Renal Transplantation

    S. Karhadkar1, J. Dawes1, K. Wirshup1, J. Kolansky1, A. Gregor1, A. Diamond2, A. DiCarlo1

    1Temple University Hospital, Philadelphia, PA, 2-, Garnet Valley, PA

    *Purpose: Living donor kidney transplantation (LDKT) continues to become a more prevalent treatment method for ESRD and is known to increase both organ availability and…
  • 2022 American Transplant Congress

    A Patient and Family Decision Support Tool for Kidney Organ Offer Decisions

    C. Schaffhausen1, A. Hart2, S. Chu3, A. K. Israni2, J. Synder1

    1Hennepin Healthcare Research Institute, Minneapolis, MN, 2Hennepin Healthcare / University of Minnesota, Minneapolis, MN, 3University of Minnesota, Saint Paul, MN

    *Purpose: For kidney transplant candidates and their care team, deciding to accept a donor organ with known or potential risk factors can be stressful and…
  • 2022 American Transplant Congress

    Single Kidney Transplantation from Small Pediatric Donors Aged < 2 Years Into Pediatric Recipients: A Retrospective Single-Center Cohort Study

    Q. Zhang, M. Huang, J. Li, W. Wu, H. Zhang, C. Wu, Q. Fu, P. Gao, L. Ling, W. Chen, B. Xu, X. Su, L. Liu, C. Wang

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China

    *Purpose: Kidneys from small pediatric donors (aged < 2 years, SPD) are underutilized. Concerns regarding potentially inferior outcomes hinder the use in pediatric recipients, especially…
  • 2022 American Transplant Congress

    An Acceptable Challenge for Specialized Transplant Centres: Small Kidney Donors for Small Recipients

    R. Büscher, M. Cetiner, P. F. Hoyer, A. K. Büscher

    Department of Pediatrics II, University Hospital Essen, Essen, Germany

    *Purpose: Kidneys from small donors (SDK, donor weight
  • 2022 American Transplant Congress

    Cold Ischemic Time and Kidney Graft Failure; Mediation Through Delayed Graft Function

    J. Miller1, W. Irish2, D. Sawinski3, A. Massie4, J. Snyder1

    1Scientific Registry of Transplant Recipients, Minneapolis, MN, 2Department of Surgery, East Carolina University, Greenville, NC, 3Division of Nephrology and Hypertension, Weill Cornell Medical College, New York, NY, 4Division of Surgery, Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: Delayed graft function (DGF) has been associated with decreased graft survival and prolonged cold ischemia time (CIT) has been proposed as a modifiable DGF…
  • 2022 American Transplant Congress

    Single Nuclei RNA-Sequencing Identifies Distinct Immune Cell Profile in Kidney Allograft Fibrosis

    J. McDaniels1, A. Shetty1, C. Kuscu2, C. Kuscu2, T. Rousselle1, E. Bardhi1, C. Drachenberg1, M. Talwar2, J. Eason2, T. Muthukumar3, D. Maluf1, V. Mas1

    1University of Maryland Baltimore, Baltimore, MD, 2UTHSC, Memphis, TN, 3Weill Cornell Medicine, New York, NY

    *Purpose: A major obstacle after kidney transplantation (KT) is chronic allograft dysfunction characterized by interstitial fibrosis and tubular atrophy (IFTA). Despite extensive research, the cellular…
  • 2022 American Transplant Congress

    A Randomized Phase 2 Study Of Mau868 Vs Placebo To Treat Bk Viremia In Kidney Transplant Recipients

    S. Jordan1, A. P. Limaye2, B. Fischbach3, P. Sood4, S. Collette5, L. Gasink6, M. W. Fordyce7, C. J. Lin7, M. Hodges6, D. C. Brennan8

    1Cedars-Sinai Medical Center, Los Angeles, CA, 2University of Washington, Seattle, WA, 3Dallas Nephrology Associates, Inc, Dallas, TX, 4University of Pittsburgh Medical Center, Pittsburgh, PA, 5Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada, 6previous employee/consultant for Amplyx Pharmaceuticals, San Diego, CA, 7Vera Therapeutics, Inc, Brisbane, CA, 8Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: To assess the safety and efficacy of MAU868, a BK virus-specific monoclonal antibody, in adult kidney transplant recipients with BK viremia.*Methods: This is a…
  • 2022 American Transplant Congress

    Cold Ischemia Time is More Critical for Older Donor Kidney Survival: A Machine Learning Approach

    J. Kim, J. Ahn, A. Massie, D. Segev, S. Bae

    Johns Hopkins, Baltimore, MD

    *Purpose: Increasing utilization of kidneys from older donors is a potential solution to mitigate the organ shortage. However, older donor age is a risk factor…
  • 2022 American Transplant Congress

    ESRD is Increasing Faster After Living Kidney Donation Than it Does in the Unselected US Population: A New Risk Metric?

    R. W. Steiner

    UCSD School of Medicine, San Diego, San Diego, CA

    *Purpose: ESRD rates increase exponentially both after kidney donation and as the US population ages. Increases in ESRD rates from the first to the second…
  • 2022 American Transplant Congress

    Superoxide in Cardiac Allografts from Donors After Circulatory Death

    M. Urban1, T. Bruett2, K. F. Duncan1, N. W. Markin3, M. M. Chacon3, M. C. Zimmerman4

    1Department of Surgery. Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE, 2College of Medicine. Department of Cellular and Integtrative Physiology., University of Nebraska Medical Center, Omaha, NE, 3Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, 4Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE

    *Purpose: Quality of cardiac allografts from donors after circulatory death (DCD) is adversely impacted by warm ischemia and subsequent reperfusion during organ resuscitation. Post-transplant myocardial…
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