ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Transplant Center Effect on Acute Liver Failure Outcomes in a National Cohort

    N. Z. Wong, K. R. Reddy, T. Bittermann

    University of Pennsylvania, Philadelphia, PA

    *Purpose: Transplant centers coordinate complex care for patients with acute liver failure (ALF), in whom liver transplantation (LT) can be lifesaving. This study examines associations…
  • 2020 American Transplant Congress

    Bariatric Surgery to Improve Candidacy for Liver Transplantation: A Systematic Review and Meta-Analysis

    J. Purvis1, R. Stahl1, J. Grams1, M. Gray1, D. Eckhoff1, R. Cannon1, C. Lewis1, N. Terrault2, J. Locke1, B. Orandi1

    1University of Alabama at Birmingham, Birmingham, AL, 2University of Southern California, Los Angeles, CA

    *Purpose: As non-alcoholic steatohepatitis grows as an indication for liver transplant, the challenge managing obese pre-liver transplant patients will become more pronounced, especially because most…
  • 2020 American Transplant Congress

    Marginal Livers Have Excellent Outcomes in Pediatric Patients with Metabolic Liver Disease

    M. MacConmara, C. Feizpour, D. Desai, S. Hanish, P. Vagefi, A. Aqul, C. S. Hwang

    UT Southwestern, Dallas, TX

    *Purpose: Pediatric patients with metabolic diseases are listed so that livers are preferentially allocated to them, having the option of receiving a very high quality…
  • 2020 American Transplant Congress

    Adult Liver Transplant Recipients Show Increased Fibrinolysis Resistance Compared with Pediatric Recipients: The Potential Impact of Anticoagulation between the Two Populations

    H. B. Moore, T. Nydam, R. Choudhury, A. Schulick, C. Walker, M. Wachs, M. A. Adams

    University of Colorado, Aurora, CO

    *Purpose: Fibrinolytic changes in adult liver transplant patients have previously been demonstrated large transitions from excessive fibrinolysis (hyperfibrinolysis) to fibrinolysis resistance (shutdown) within 2 hours…
  • 2020 American Transplant Congress

    Duration of Pre-Transplant Abstinence Does Not Predict Severe Relapses of Alcohol Abuse in High-Risk Alcoholic Liver Transplant Recipients

    W. H. Kitchens

    Emory Transplant Center, Atlanta, GA

    *Purpose: The traditional requirement of >6 months pre-transplant sobriety for liver transplant recipients has been challenged by emerging literature, but risk factors for post-transplant recidivism…
  • 2020 American Transplant Congress

    Long-Term Liver Transplant Outcomes: A Single Center Cohort Study

    S. A. Mao, K. P. Croome, I. J. Galler, C. B. Taner

    Mayo Clinic Florida, Jacksonville, FL

    *Purpose: This single center study reviews long-term outcomes of liver transplantation identifying morbidity differences between post-transplant liver patients surviving greater than five years versus those…
  • 2020 American Transplant Congress

    Validation of Patient Reported Outcomes Measurement Information System (PROMIS) Computer Adaptive Testing Depression Item Bank in Kidney Transplant Recipients

    V. Shah1, A. Rezaeishahreza1, E. Lui1, R. Aser1, S. Bartlett2, M. Li1, D. Howell1, J. Peipert3, M. Novak1, I. Mucsi1

    1University Health Network, Toronto, ON, Canada, 2McGill University, Montreal, QC, Canada, 3Northwestern University, Chicago, IL

    *Purpose: To evaluate the reliability and validity of the PROMIS Depression computerized adaptive test (PROMIS-D CAT) in relation to a legacy measure in adult Kidney…
  • 2020 American Transplant Congress

    Statin Use May Be Associated with Lower Risk of Invasive Aspergillosis in Lung Transplant Recipients

    A. Perez Cortes Villalobos, F. Foroutan, S. Davoudi, T. Martinu, J. Tikkanen, L. Singer, S. Keshavjee, S. Husain

    University Health Network, Toronto, ON, Canada

    *Purpose: Statins are competitive inhibitors of HMG-CoA reductase, that catalyses the conversion of HMG-CoA to mevalonate, which is involved in the synthesis of cholesterol in…
  • 2020 American Transplant Congress

    Pharmacokinetics of Maribavir in Subjects with Moderate Hepatic Impairment

    I. H. Song1, K. Ilic2, J. Wu3

    1Quantitative Clinical Pharmacology, Shire, a Takeda Company, Lexington, MA, 2Rare Disease TAU, Shire, a Takeda Company, Lexington, MA, 3Biostat, Shire, a Takeda Company, Lexington, MA

    *Purpose: Maribavir, an investigational agent for cytomegalovirus (CMV) infection in transplant recipients, has received Breakthrough Therapy Designation. Maribavir is metabolized primarily in the liver through…
  • 2020 American Transplant Congress

    Artificial Intelligence May Predicts Early Sepsis in Liver Transplantation

    R. D. Kamaleswaran1, R. Lowell Davis2, J. D. Eason3, S. Sataphaty4, V. R. Mas5, D. Maluf3

    1Biostatistics, Emory, Atlanta, GA, 2Center for Biomedical Informatics & Division of Critical Care Medicine, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, 3Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, 4Sandra Atlas Bass Center for Liver Diseases & Transplantation, Northshore University Hospital/Northwell Health, NSHS, NY, 5Biostatistics, Emory, Atlanta, TN

    *Purpose: Sepsis post liver transplantation is a frequent challenge impacting patient outcomes. We aimed to develop an artificial intelligence method to predict earlier the onset…
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