Abstracts Archive - Page 39 of 1683 - ATC Abstracts

2022 American Transplant Congress
Perfusate Il-6 Levels During Liver Nmp Are Predictive For Hemodynamic Response And Catecholamine Demand After Reperfusion In The Recipient
A. Weissenbacher¹, S. Mathis², B. Cardini¹, C. Bogensperger¹, G. Putzer², L. Gasteiger², T. Resch¹, R. Oberhuber¹, D. Öfner¹, T. Hell³, J. Martini², S. Schneeberger¹
¹Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria, ²Department of Anaesthesiology and Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria, ³Department of Mathematics, Faculty of Mathematics, Computer Science and Physics, University of Innsbruck, Innsbruck, Austria
*Purpose: Normothermic liver preservation (NMP) has become a clinical routine at several transplant centres. Reperfusion-syndrome occurs less often in recipients of NMP-livers compared to cold…
2022 American Transplant Congress
Targeted Delivery of Costimulation Inhibitor to Lymph Nodes Promotes Transplant Tolerance via Fibroblastic Reticular Cells
J. Zhao¹, S. Jung¹, X. Li¹, H. Zhang¹, S. Movahedi¹, V. Kasinath¹, M. Uehara¹, J. Azzi¹, P. Sage¹, S. Tullius¹, J. S. Bromberg², R. Abdi¹
¹Brigham and Women's Hospital, Boston, MA, ²University of Maryland School of Medicine, Baltimore, MD
*Purpose: The lymph node (LN) is the primary site of alloimmunity activation and regulation during transplantation. Fibroblastic reticular cells (FRCs), the prominent cells of the…
2022 American Transplant Congress
Covid-19 Vaccination Response In Tacrolimus Treated Kidney Transplant Recipients With And Without Mycophenolate Mofetil: Follow-up Of A Randomized Controlled Trial
Z. Al Fatly¹, M. G. Betjes¹, A. L. Messchendorp², J. S. Sanders², M. E. Reinders¹, M. M. Kho¹, A. E. de Weerd¹
¹Department of Internal Medicine, Erasmus MC Transplant Institute University Medical Center, Rotterdam, Netherlands, ²Department of Internal Medicine, Groningen Medical Center, Groningen, Netherlands
*Purpose: To investigate the effect of mycophenolate mofetil (MMF) on SARS-CoV-2 vaccination response in kidney transplant recipients using the standard immunosuppressive regimen of tacrolimus (TAC)…
2022 American Transplant Congress
Early Clinical Experience With Alvr109, A Partially Hla-matched Sars-cov-2 Specific T-cell Therapy, In Immunocompromised Patients With Covid-19
G. Haidar¹, J. Jacobs², K. Hughes², K. McCormick², A. Naqvi², M. Agha², T. Bogdanovich², B. Johnson², J. Kozar², E. Lendermon², C. Marino², A. Raptis², F. Silveira², W. Marshall³, M. Miller³, E. Atillasoy³, J. Mellors²
¹University of Pittsburgh, Pittsburgh, PA, ²UPitt, Pittsburgh, PA, ³Allovir, Waltham, MA
*Purpose: Therapies for COVID-19 in immunocompromised (IC) patients (pts), including transplant (tx) pts, are limited. We describe our experience with ALVR109, an allogeneic, partially HLA-matched…
2022 American Transplant Congress
A Patient and Family Decision Support Tool for Kidney Organ Offer Decisions
C. Schaffhausen¹, A. Hart², S. Chu³, A. K. Israni², J. Synder¹
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²Hennepin Healthcare / University of Minnesota, Minneapolis, MN, ³University of Minnesota, Saint Paul, MN
*Purpose: For kidney transplant candidates and their care team, deciding to accept a donor organ with known or potential risk factors can be stressful and…
2022 American Transplant Congress
Single Kidney Transplantation from Small Pediatric Donors Aged < 2 Years Into Pediatric Recipients: A Retrospective Single-Center Cohort Study
Q. Zhang, M. Huang, J. Li, W. Wu, H. Zhang, C. Wu, Q. Fu, P. Gao, L. Ling, W. Chen, B. Xu, X. Su, L. Liu, C. Wang
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China
*Purpose: Kidneys from small pediatric donors (aged < 2 years, SPD) are underutilized. Concerns regarding potentially inferior outcomes hinder the use in pediatric recipients, especially…
2022 American Transplant Congress
An Acceptable Challenge for Specialized Transplant Centres: Small Kidney Donors for Small Recipients
R. Büscher, M. Cetiner, P. F. Hoyer, A. K. Büscher
Department of Pediatrics II, University Hospital Essen, Essen, Germany
*Purpose: Kidneys from small donors (SDK, donor weight
2022 American Transplant Congress
Cold Ischemic Time and Kidney Graft Failure; Mediation Through Delayed Graft Function
J. Miller¹, W. Irish², D. Sawinski³, A. Massie⁴, J. Snyder¹
¹Scientific Registry of Transplant Recipients, Minneapolis, MN, ²Department of Surgery, East Carolina University, Greenville, NC, ³Division of Nephrology and Hypertension, Weill Cornell Medical College, New York, NY, ⁴Division of Surgery, Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Delayed graft function (DGF) has been associated with decreased graft survival and prolonged cold ischemia time (CIT) has been proposed as a modifiable DGF…
2022 American Transplant Congress
Single Nuclei RNA-Sequencing Identifies Distinct Immune Cell Profile in Kidney Allograft Fibrosis
J. McDaniels¹, A. Shetty¹, C. Kuscu², C. Kuscu², T. Rousselle¹, E. Bardhi¹, C. Drachenberg¹, M. Talwar², J. Eason², T. Muthukumar³, D. Maluf¹, V. Mas¹
¹University of Maryland Baltimore, Baltimore, MD, ²UTHSC, Memphis, TN, ³Weill Cornell Medicine, New York, NY
*Purpose: A major obstacle after kidney transplantation (KT) is chronic allograft dysfunction characterized by interstitial fibrosis and tubular atrophy (IFTA). Despite extensive research, the cellular…
2022 American Transplant Congress
A Randomized Phase 2 Study Of Mau868 Vs Placebo To Treat Bk Viremia In Kidney Transplant Recipients
S. Jordan¹, A. P. Limaye², B. Fischbach³, P. Sood⁴, S. Collette⁵, L. Gasink⁶, M. W. Fordyce⁷, C. J. Lin⁷, M. Hodges⁶, D. C. Brennan⁸
¹Cedars-Sinai Medical Center, Los Angeles, CA, ²University of Washington, Seattle, WA, ³Dallas Nephrology Associates, Inc, Dallas, TX, ⁴University of Pittsburgh Medical Center, Pittsburgh, PA, ⁵Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada, ⁶previous employee/consultant for Amplyx Pharmaceuticals, San Diego, CA, ⁷Vera Therapeutics, Inc, Brisbane, CA, ⁸Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: To assess the safety and efficacy of MAU868, a BK virus-specific monoclonal antibody, in adult kidney transplant recipients with BK viremia.*Methods: This is a…