Abstracts Archive - Page 378 of 1683 - ATC Abstracts

2020 American Transplant Congress
Cancer Risk in Living Kidney Donors (LKDs) in the United States
E. Engels¹, K. Yu¹, S. Brown¹, K. Pawlish², C. Lynch³, B. Kasiske⁴, J. Snyder⁴, R. Pfeiffer¹
¹National Cancer Institute, Bethesda, MD, ²New Jersey Dept of Health, Trenton, NJ, ³Univ of Iowa, Iowa City, IA, ⁴Scientific Registry of Transplant Recipients, Minneapolis, MN
*Purpose: Individuals who wish to donate a kidney for transplantation are evaluated for transmissible diseases (including cancer) prior to donation. Outcomes in LKDs after donation…
2020 American Transplant Congress
A Large Animal Model of Ex-Vivo Lung Perfusion as a Platform to Deliver Therapeutic Agents to Lungs Before Lung Transplant
T. M. Egan¹, B. Haithcock¹, M. H. Ali¹, J. W. Blackwell¹, B. Masuodi¹, S. Shipley², T. Long³, A. Akerman¹, S. Montgomery⁴, H. Yuan⁵, P. Stewart⁶, J. Potenziano⁷, C. Sekaran⁷, R. Fitch⁷
¹Surgery, UNC at Chapel Hill, Chapel Hill, NC, ²Department of Pathology and Laboratory Medicine, UNC at Chapel Hill, Chapel Hill, NC, ³Pathology and Laboratory Medicine,, UNC at Chapel Hill, Chapel Hill, NC, ⁴Pathology and Laboratory Medicine, UNC at Chapel Hill, Chapel Hill, NC, ⁵Radiology, UNC at Chapel Hill, Chapel Hill, NC, ⁶Gillings Global School of Public Health, UNC at Chapel Hill, Chapel Hill, NC, ⁷Mallinckrodt Pharmaceuticals, Hazelwood, MO
*Purpose: Ex-vivo lung perfusion (EVLP) has been used to evaluate lung function before lung transplant (LT). We used EVLP to expose lungs recovered 6 hours…
2020 American Transplant Congress
Donor Lung Travel Distance and Time
C. Lehr¹, M. Skeans², M. Valapour¹, E. Lease³
¹Cleveland Clinic, Cleveland, OH, ²SRTR, Minneapolis, MN, ³University of Washington, Seattle, WA
*Purpose: With the policy change from donation service area (DSA) to 250 nautical miles (NM) as the first unit of US lung allocation, distances between…
2020 American Transplant Congress
Epidemiology of Non-Aspergillus Mold in Lung Transplant Recipients at a Large Transplant Center
J. A. Morillas¹, F. J. Marco Canosa¹, H. Hassouna², K. Brizendine¹
¹Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH, ²Infectious Disease, Spectrum Health Medical Group-Michigan State University College of Human Medicine, Grand Rapids, MI
*Purpose: Invasive fungal infections (IFI) remain a significant cause of mortality among lung transplant recipients (LTR). The emergence of non-Aspergillus molds has become a concern…
2020 American Transplant Congress
Impact of Donor Lung Pathogenic Bacteria Detected by Next-Generation Sequencing on Early Post-Transplant Outcomes in Lung Transplant Recipients
D. Liu, J. Zhang, J. Chen
Lung Transplant Center, Wuxi People's Hospital, Wuxi, China
*Purpose: The effect of donor lung pathogenic bacteria on the prognosis of lung transplantation is not clear. We used the technique of next-generation sequencing (NGS)…
2020 American Transplant Congress
Lung Mucosal Biopsies Deteriorate with Time Post-Transplant: A Molecular Analysis
M. D. Parkes¹, P. Halloran¹, K. Halloran², &. the INTERLUNG Study Group³
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³., ., AB, Canada
*Purpose: Mucosal biopsies from the third airway bifurcation (3BMBs) assessed molecularly can be used to detect rejection (DOI: 10.1111/ajt.15685), and may also provide insights into…
2020 American Transplant Congress
Monitoring the Removal of Donation Service Area from Lung Allocation
R. R. Goff¹, R. Daly², E. D. Lease³
¹Research, United Network for Organ Sharing, Richmond, VA, ²Mayo Clinic, Rochester, MN, ³University of Washington, Seattle, WA
*Purpose: In 2017 the Organ Procurement and Transplantation Network (OPTN) altered US lung allocation policy by replacing the donor service area (DSA) with a 250…
2020 American Transplant Congress
Simultaneous Pancreas-Kidney Transplant: – The Effects of Early Steroid Withdrawal, Donor and Recipient Variables on Patient Survival
D. Kloda¹, M. McLeod², M. Romine¹, J. Ladowski², J. Locke¹, C. Young¹
¹Department of Surgery - Division of Transplantation, University of Alabama, Birmingham, AL, ²Department of Surgery, University of Alabama, Birmingham, AL
*Purpose: Simultaneous pancreas-kidney transplantation (SPK) improves survival in type I diabetic patients with end stage renal disease (ESRD). Corticosteroids have traditionally been an integral component…
2020 American Transplant Congress
Oral versus Intravenous Mycophenolate Mofetil Administration: A Single Center Experience on Incidence of Acute Kidney Injury
P. Chung¹, K. Forrester², S. Ganesh¹
¹Division of Pulmonary Critical and Sleep Medicine, University of Southern California, Los Angeles, CA, ²Department of Clinical Pharmacy, University of Southern California School of Pharmacy, Los Angeles, CA
*Purpose: Mycophenolate mofetil (MMF) is one of the main immunosuppressive medications given in lung transplantation (LTx). It is given orally (PO) or intravenously (IV). In…
2020 American Transplant Congress
Ion AmpliSeq RNA Expression Panel Evaluated by Next-Generation Sequencing (NGS) Can Detect Genes in Human Formalin-Fixed Paraffin-Embedded Kidney Biopsies to Predict T Cell and Antibody Mediated Rejection in Renal Allografts
P. Ruiz¹, E. Margolles-Clark¹, G. Guerra², A. Mattiazzi², M. Ortigosa-Goggins², G. Ciancio¹, L. Chen¹, G. Burke¹
¹Surgery, University of Miami, Miami, FL, ²University of Miami, Miami, FL
*Purpose: Optimization of effective anti-rejection therapies to prevent allograft rejection and to minimize drug toxicity may be aided by utilizing in situ biomarkers for detection…