ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Reflections on the Most Prolific United States Kidney Transplant Surgeon: A Career That Helped Define the Standard of Transplant Care

    C. Killian1, R. Reed2, P. MacLennan1, D. Anderson1, R. Cannon1, B. Orandi1, P. Porrett1, S. Sheikh1, C. Young1, M. J. Hanaway1, J. Locke1

    1University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Irondale, AL

    *Purpose: The standard of care in kidney transplantation has evolved with advances in immunosuppressive therapy. Few transplant surgeons experienced the realization of these advances firsthand.…
  • 2022 American Transplant Congress

    Comparison of Statin-Associated Adverse Events Across Different Types of Statins in Kidney Transplant Recipients

    S. Bae1, J. Ahn2, M. A. Schnitzler3, K. Lentine4, D. Segev1, M. McAdams-DeMarco1

    1Johns Hopkins University, Baltimore, MD, 2SOM, Johns Hopkins University, Baltimore, MD, 3Surgery, Saint Louis University, St. Louis, MO, 4Saint Louis University, St. Louis, MO

    *Purpose: Statins are the third most prescribed drug class in kidney transplant (KT) recipients. Statin’s safety profile in KT recipients remains unclear, although these individuals…
  • 2022 American Transplant Congress

    Incidence of Delayed Graft Function in Kidneys Recovered After Normothermic Regional Perfusion

    L. James1, M. D'Angelo1, J. Carillo1, J. C. Berger1, D. E. Smith1, N. Moazami1, B. Lonze2

    1NYU Langone Health, New York, NY, 2NYU Langone Transplant Institute, New York, NY

    *Purpose: The use of normothermic reperfusion (NRP) following donation after circulatory death (DCD) is an emerging strategy for organ procurement. NRP technique reestablishes circulatory blood…
  • 2022 American Transplant Congress

    Implications of Accumulated Cold Time for US Kidney Transplantation Offer Acceptance

    M. Barah1, V. Kilambi2, J. Friedewald1, S. Mehrotra1

    1Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL, 2Department of Engineering and Applied Sciences, RAND Corporation, Arlington, VA

    *Purpose: Reducing discard is a current focus in US transplantation of deceased donor kidneys. One cause for the discards is the avoidance of protracted cold…
  • 2022 American Transplant Congress

    Understanding the Response of Human Lung Microvascular Endothelial Cells During Lung Transplantation via an In Vitro Model of Ischemia Reperfusion Injury

    L. Chacon Alberty1, M. King1, G. Loor2, E. Curty1, C. Hochman-Mendez1

    1Regenerative Medicine Research, Texas Heart Institute, Houston, TX, 2Baylor College of Medicine - Lung Transplant, Houston

    *Purpose: Lung Transplantation (LTx) is a therapeutic option for patients with end-stage lung disease. One of the major complications is primary graft dysfunction largely attributed…
  • 2022 American Transplant Congress

    Dual Therapy with Esculin and Erythropoietin Attenuates Renal Ischemia-Reperfusion Injury via P2x7 Receptor and Nlrp3 Inflammasome Inhibition, and Pi3k/akt Activation

    E. Hafiz1, W. H. El-Maadawy2, M. Hassan3, M. H. Badawy4, S. Eldahshan4, A. AbuSeada5

    1Clinical Research Laboratory Department, Theodor Bilharz Research Institute, Giza, Egypt, 2Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt, 3Immunology Department, Theodor Bilharz Research Institute, Giza, Egypt, 4Urology Department, Theodor Bilharz Research Institute, Giza, Egypt, 5Anesthesia Department, Theodor Bilharz Research Institute, Giza, Egypt

    *Purpose: Renal ischemia/reperfusion (RI/R) is an inevitable condition during renal transplantation with critical clinical outcomes. Accordingly, effective therapies are crucially required.*Methods: In this study, the…
  • 2022 American Transplant Congress

    Case Times For Brain Dead Donors: Longer Is Not Better, No Impact Of Longer Case Time On Organ Yield Or OPO Performance Tier

    M. J. Moritz1, R. Hasz1, H. Nathan1, E. Hunt2, S. Noreen3, A. Toll4

    1Gift of Life Donor Program, Philadelphia, PA, 2Surgery, Lehigh Valley Health Network, Allentown, PA, 3United Network for Organ Sharing, Richmond, VA, 4Research, United Network for Organ Sharing, Silverdale, WA

    *Purpose: Having observed the steady increase in case times, we wished to examine if this has impacted organ yield*Methods: We conducted a retrospective cohort study…
  • 2022 American Transplant Congress

    Tissue Engineering Scaffolds for Minimally Invasive Immunosurveillance of Acute Cellular Graft Rejection

    R. R. Urie1, D. Farris2, A. Morris1, E. Lombard1, J. Z. Li3, D. Goldstein2, L. Shea1

    1Biomedical Engineering, University of Michigan, Ann Arbor, MI, 2Internal Medicine, University of Michigan, Ann Arbor, MI, 3Human Genetics, University of Michigan, Ann Arbor, MI

    *Purpose: As there is no assay to predict the risk of acute cellular allograft rejection (ACAR), clinicians rely on protocol graft biopsy and aggressive, one-size-fits-all…
  • 2022 American Transplant Congress

    Pericardial Effusion: A Potential Late Complication of COVID-19 Infection

    O. Sogbein, A. Rizvi, M. Mujtaba, S. Hussain

    Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX

    *Purpose: COVID-19 infection involves entry of SARS-CoV-2 virus into cells via interaction between its spike protein and angiotensin converting enzyme resulting in an NF-κβ mediated…
  • 2022 American Transplant Congress

    Semaglutide Tolerability and Efficacy in Patients with Chronic Kidney Disease Stage 4, 5 and End Stage Renal Disease

    J. J. Long, A. Lemke, V. Sudhindran, N. Pencovici, A. Kukla, T. Diwan

    Mayo Clinic, Rochester, MN

    *Purpose: Obesity is often a barrier to kidney transplantation (KT) due to increased perioperative risks and worse outcomes with many transplant centers setting BMI cut…
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