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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Safety and Efficacy of SGLT-2 Inhibitors in Solid Organ Transplant Recipients

    E. Heiman, D. Blanco, A. Webb

    Pharmacy, Tampa General Hospital, Tampa, FL

    *Purpose: Sodium-glucose co-transporter 2 inhibitors (SGLT2i) have been shown to improve glycemic control, blood pressure, cardiovascular mortality, and preserve kidney function in the general population.…
  • 2022 American Transplant Congress

    Invasive Fungal Infections Associated with COVID-19 Infections in Solid Organ Transplant Recipients

    R. Alameer, M. Nguyen, P. Samanta

    Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Invasive fungal infection (IFI) complicating Coronavirus disease of 2019 (COVID-19) has been increasingly recognized. IFI is a common opportunistic infection in solid organ transplant…
  • 2022 American Transplant Congress

    Deceased Donor Kidney Transplantation from Donors with Acute Kidney Injury: Realities and Costs

    S. Iskhagi1, R. Shahbazov1, A. Ball1, S. Loerzel1, E. Shaban2, B. Gallay2, R. Hod Dvorai3, J. Leggat2, M. Hanlon1, R. Saidi1

    1Department of Surgery, Division of Transplantation, SUNY Upstate Medical University, Syracuse, NY, 2Department of Medicine, Division of Nephrology, SUNY Upstate Medical University, Syracuse, NY, 3Department of Pathology and Laboratory Medicine, SUNY Upstate Medical University, Syracuse, NY

    *Purpose: The use of kidneys from deceased donors with acute kidney injury (AKI) is one of the options to expand donor pool. Several studied have…
  • 2022 American Transplant Congress

    Outcomes After Deceased Donor Kidney Transplantation Utilizing Kidney Allografts with Marginal Perfusion Parameters: A Single-Center Experience

    P. N. Chotai1, A. Logan2, F. Siddiqui3, A. Schenk4, G. Bumgardner5, G. L. Brock2, A. El-Hinnawi5, A. Rajab6, K. Washburn7, N. Singh2

    1Division of Transplantation, Department of General Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, 2The Ohio State University Wexner Medical Center, Columbus, OH, 3Ohio State University, Bloomfield, NJ, 4Ohio State University Wexner Medical Center, Bexley, OH, 5Ohio State University, Columbus, OH, 6Ohio State University Wexner Medical Center, Columbus, OH, 7The Ohio State University, Columbus, OH

    *Purpose: To study outcomes of deceased donor kidney transplantation (DDKT) in recipients of kidney allografts with poor perfusion parameters.*Methods: This is a retrospective, single center…
  • 2022 American Transplant Congress

    The Impact of the New Allocation System of Kidney Transplantation on a Single Institution

    M. Eltemamy, Y. Lin, M. Khalil, S. Agrawal, V. Krishnamurthi, A. Wee

    The Cleveland Clinic, Cleveland, OH

    *Purpose: The new kidney allocation system went into effect in the middle of March 2021. The consequences of this new system affected transplant centers differently,…
  • 2022 American Transplant Congress

    Site-Directed Mutagenesis as a Tool to Investigate Immunogenicity of HLA Epitopes for Humoral Alloreactivity

    C. H. Maguire1, P. Crivello2, A. Tambur1

    1Northwestern University, Chicago, IL, 2University Hospital Essen, Essen, Germany

    *Purpose: Molecular mismatch load (MML) analysis has been a proposed approach to assess donor/recipient compatibility in support of organ allocation algorithms. While conceptually appealing, MML…
  • 2022 American Transplant Congress

    Cardiovascular Outcomes of Kidney Transplant Recipients Receiving Belatacept Compared to a Matched Tacrolimus

    Y. Kim1, J. Marvin1, K. Belfield1, G. Girone1, R. Formica2, E. Cohen1

    1Pharmacy, Yale New Haven Hospital, New Haven, CT, 2Section of Nephrology, Yale School of Medicine, New Haven, CT

    *Purpose: Tacrolimus (TAC), a calcineurin inhibitor (CNI), is the backbone of maintenance immunosuppression in kidney transplant recipients (KTR) but has been associated with cardiovascular (CV)…
  • 2022 American Transplant Congress

    Sirolimus Regimens After Kidney Transplantation: Role of Pre-Transplant Risk Factors in Modifying the Risk of Mortality in Adult Recipients

    A. Santos1, H. Ibrahim1, M. A. Leghrouz1, X. Wen2

    1University of Florida, Gainesville, FL, 2University of Rhode Island, Kinston, RI

    *Purpose: We aimed to investigate the role of risk factors in modifying the association of sirolimus with mortality in kidney transplant (KT) recipients (KTRs).*Methods: Using…
  • 2022 American Transplant Congress

    Defects in Kim-1 Do Not Result In Delayed Graft Function After Kidney Transplantation

    R. S. Suri1, J. Lee2, M. Ban3, B. Shrum2, O. Z. Ismail4, S. Leckie5, A. McIntyre3, Q. Xu6, S. H. Lee2, S. de Chickera2, R. A. Hegele2, L. Gunaratnam2

    1Research Institute of the McGill University Health Center, Montreal, QC, Canada, 2Schulich School of Medicine and Dentistry, Western University, Lodnon, ON, Canada, 3Robarts Research Institute, Lodnon, ON, Canada, 4University of Alberta, Edmonton, AB, Canada, 5London Health Sciences Centre, Lodnon, ON, Canada, 6University of Pittsburg Medical Center, Pittsburg, PA

    *Purpose: Tissue repair is critical to restore organ function after ischemia-reperfusion injury (IRI) during transplantation. During renal injury, upregulation of kidney injury molecule-1 (KIM-1) transforms…
  • 2022 American Transplant Congress

    Preferred Language And Disease Severity Predict Evaluation For Liver Transplantation Among Patients Admitted With Alcoholic Hepatitis

    D. J. Cloonan1, J. Broekhuis2, T. Coe1, S. Criss3, S. Li3, E. Bethea1, H. Yeh1, L. Dageforde1

    1Massachusetts General Hospital/Harvard Medical School, Boston, MA, 2Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, 3Harvard Medical School, Boston, MA

    *Purpose: Liver transplantation (LT) for alcoholic hepatitis (AH) without a sobriety period is a relatively new practice. While AH patients are no longer categorically excluded…
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