ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Treatment of Hepatic Encephalopathy in Cirrhotic Patients: Does Rifaximin Prevent Clostridioides Difficile Infection? A Retrospective Analysis

    J. D. Goldman, V. Aleksenko, J. L. Davila, N. A. Muhktar, K. Kowdley

    Swedish Medical Center, Seattle, WA

    *Purpose: Clostridioides difficile infection (CDI) is a major cause of morbidity and mortality and new prevention strategies in high-risk patients are needed. Rifaximin has been…
  • 2020 American Transplant Congress

    Use of 16S Sequencing to Reveal Potential Respiratory Pathogens in Lung Transplant Recipients

    C. Eskind1, M. Shilts1, H. Boone1, J. Schmitz2, C. Shaver3, S. Das1, G. Satyanarayana1

    1Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, 2Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, 3Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Respiratory infections are common after lung transplant and contribute to mortality and allograft failure. 16S ribosomal RNA (rRNA) gene sequencing could facilitate diagnosis of…
  • 2020 American Transplant Congress

    Correlation of CMV and EBV DNAemia in the Development of Invasive Fungal Disease among Pediatric Intestinal and Liver Transplant Recipients

    B. M. Chatani1, J. Garcia2, T. Beduschi3, A. Tekin3, R. Vianna3, I. A. Gonzalez1

    1Pediatric Infectious Disease, University of Miami Miller School of Medicine, Miami, FL, 2Pediatric Gastroenterology, University of Miami Miller School of Medicine, Miami, FL, 3Miami Transplant Institute, Miami, FL

    *Purpose: Invasive fungal disease (IFD) among pediatric solid organ transplant recipients is a relatively rare event, however often results in death. There are many factors…
  • 2020 American Transplant Congress

    Temporal Trends in the Incidence and Impact of Infections Following Kidney Transplantation

    K. R. Jackson, J. Motter, R. Avery, W. Werbel, J. Garonzik-Wang, D. Segev

    Johns Hopkins University, Baltimore, MD

    *Purpose: Infections remain a major threat to successful kidney transplantation (KT), and are associated with a subsequent higher risk of mortality and graft loss. However,…
  • 2020 American Transplant Congress

    The Level of Plasm Donor-Derived Cell-Free DNA in Kidney Transplant Patients with Severe Pneumonia

    L. Liu1, H. Liu2, F. Liu2, L. Shu2, L. Peng1

    1Xiangyang Hospital No. 2 of Central South University, Changsha, China, 2AlloDx, Shanghai; Suzhou, China

    *Purpose: Pulmonary infection is one of the common complications after kidney transplantation. Donor-derived cell-free DNA (ddcfDNA) is a new biomarker to diagnose allograft injury. Currently,…
  • 2020 American Transplant Congress

    Rates of Live Donor Liver Transplantation Vary by Socioeconomic Status and Geography

    D. R. Jorgensen, A. Humar, C. Hughes, M. Molinari, A. Ganoza, S. Ganesh, A. Duarte-Rojo, A. Tevar

    Surgery, University of Pittsburgh, Pittsburgh, PA

    *Purpose: Live donor liver transplantation (LDT) carries with it many benefits for the recipient, including reduced time on waitlist, transplantation at a lower meld score,…
  • 2020 American Transplant Congress

    Impact of Donor Race on Tacrolimus Dose Requirement for Liver Transplant Recipients

    N. Nesselhauf1, S. January1, J. Hagopian1, K. Progar1, A. Khan2

    1Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, 2Surgery, Washington University School of Medicine, St. Louis, MO

    *Purpose: It is well described that there is interpatient variability in tacrolimus dose requirements among transplant recipients. CYP3A5 plays a role in this variability. Black…
  • 2020 American Transplant Congress

    Risk of Infectious Complications after GastroIntestinal Surgery in Renal Transplant Recipients

    S. Karhadkar, P. Jacoby, T. Webster, A. Di Carlo

    Temple University School of Medicine, Philadelphia, PA

    *Purpose: Solid organ transplantation remains the preferred treatment for patients with end stage organ diseases. In 2018 alone, 36, 527 organ transplants were performed in…
  • 2020 American Transplant Congress

    The Relationship Between Frailty and Performance Status in Patients with Cirrhosis Awaiting Liver Transplantation

    C. Q. Xu1, F. Yao2, Y. Mohamad2, R. Wong2, D. Kent2, S. Seetharaman2, Y. Srisengfa2, J. C. Lai2

    1Department of Medicine, UCSF, San Francisco, CA, 2Division of Gastroenterology and Hepatology, Department of Medicine, UCSF, San Francisco, CA

    *Purpose: Frailty—a multi-dimensional construct that encapsulates physical function, performance status, and nutritional status—has emerged as a critical determinant of mortality in patients with cirrhosis. Currently,…
  • 2020 American Transplant Congress

    Outcomes of Intra-Operative Steroid Induction in Liver Transplant Recipients

    A. Poparad-Stezar, A. Jantz, T. Larson, B. Summers, N. Sulejmani

    Henry Ford Hospital, Detroit, MI

    *Purpose: Evidence supporting the use of antibody induction (AI) immunosuppression (IS) (antithymocyteglobulin (rATG) and basiliximab (BAS)) for acute rejection (AR) prophylaxis in liver transplant is…
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