ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Diabetes Mellitus and Blood Glucose Variability Increases the 30-day Readmission Rate After Kidney Transplantation

    H. Chakkera1, C. Cook1, S. Saghafian2, A. Orfanoudaki3

    1Mayo Clinic Arizona, Scottsdale, AZ, 2Harvard University, Boston, MA, 3University of Oxford, Oxford, United Kingdom

    *Purpose: The 30-day readmission rate is a surrogate metric of quality of care and mortality after kidney transplantation. Diabetes and observations of glucose variability during…
  • 2022 American Transplant Congress

    HLA-II Subclasses Behave Differently Between Themselves and Between Humans: Cues to Understand Alloreactivity

    S. Beland, O. Desy, M. Marcoux, M. Thivierge, J. Desgagnes, S. A. De Serres

    Transplantation Unit, Renal Division, University Health Center of Quebec, Faculty of Medicine, Universite Laval, Quebec, QC, Canada

    *Purpose: De novo anti-HLA-II DSAs (dnDSA) are associated with antibody-mediated rejection. However, some patients with anti-HLA-II DSAs will not develop rejection, suggesting that the development…
  • 2022 American Transplant Congress

    High Pretransplant FGF-23 Level is Associated with Poor Graft Survival and Persistent Vitamin D Insufficiency in Kidney Transplant Patients

    J. Ryu1, H. Jeon2, T. Koo3, J. Yang4

    1Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea, Republic of, 2Department of Internal Medicine, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea, Republic of, 3Internal Medicine, Seongnam Citizens Medical Center, Seongnam, Korea, Republic of, 4Internal Medicine, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea, Republic of

    *Purpose: Vitamin D [25(OH)D] insufficiency and FGF-23 elevation in chronic kidney disease (CKD) is usually ameliorated after kidney transplantation (KT). However, post-transplant vitamin D insufficiency…
  • 2022 American Transplant Congress

    A Large-Scale National Cohort Study Assessing the Impact of Diabetes and Obesity on Kidney Transplant Outcomes

    V. Rohan1, M. Casey1, S. Zemin2, P. Baliga2, D. Taber2

    1Surgery, Medical University of South Carolina, Charleston, SC, 2Medical University of South Carolina, Charleston, SC

    *Purpose: Type 2 Diabetes Mellitus (T2DM) is the most common cause of renal failure in patients undergoing kidney transplantation (KT) and highly correlated with obesity.…
  • 2022 American Transplant Congress

    Revision Ureteroneocystostomy in Pediatric Renal Transplant Patients for Symptomatic Vesicoureteral Reflux and Its Effect on Recurrent Hospitalizations

    P. Campbell1, M. Christman1, S. Marietti2, E. Ingulli2

    1Naval Medical Center San Diego, San Diego, CA, 2UCSD Rady Children's Hospital, San Diego, CA

    *Purpose: To evaluate the effect of revision ureteroneocystostomy on pediatric renal transplant patients with symptomatic vesicoureteral reflux (VUR) in reducing hospitalizations and recurrent urinary tract…
  • 2022 American Transplant Congress

    Angiotensin II Type 1 Receptor Antibody in Pediatric Abdominal Organ Transplant: Survey of Clinical Practice in the United States

    R. Patnaik, K. Hitchman, N. Mittal, D. Ranch, D. Fritze

    University Health Transplant Institute, San Antonio, TX

    *Purpose: Some studies correlate Angiotensin II Type 1 Receptor (AT1R) antibodies (Ab) with the development of rejection, vascular complications, and allograft dysfunction in pediatric solid…
  • 2022 American Transplant Congress

    Autophagy is an Important Factor in the Development of Fibrosis Following Renal Injury; Implications for Post-Transplant IFTA

    R. Lopez-Soler1, X. Ding2, Q. Zang3

    1Tansplant, Surgery, Edward Hines VA Medical Center, Hines, IL, 2Pathology, Loyola University Medical Center, Maywood, IL, 3Surgery, Loyola University Medical Center, Maywood, IL

    *Purpose: Interstitial Fibrosis and Tubular Atrophy (IFTA) is the most common cause of long-term graft failure following renal transplant. There is currently no effective therapy.…
  • 2022 American Transplant Congress

    Transplant Centers That Assess Frailty as Part of Clinical Practice Have Better Outcomes

    X. Chen1, Y. Liu1, V. Thompson1, N. M. Chu1, E. A. King1, J. D. Walston2, J. A. Kobashigawa3, D. M. Dadhania4, D. L. Segev1, M. A. McAdams-DeMarco1

    1Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 2Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 3Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, 4Division of Nephrology and Hypertension, Weill Cornell Medicine, New York, NY

    *Purpose: Frailty predicts adverse post-kidney transplant (KT) outcomes, yet impacts of frailty assessments on center-level outcomes remain unclear. We tested whether transplant centers assessing frailty…
  • 2022 American Transplant Congress

    An Immune-Modulatory Strategy to Mitigate Hepatic Ischemia Reperfusion Injury in a Murine Model

    S. Duarte, A. Kobayashi, V. Boominathan, A. Kwiatkowski, J. Simonovich, A. Wanchoo, G. Hudalla, B. Keselowsky, A. Zarrinpar

    University of Florida, Gainesville, FL

    *Purpose: Hepatic ischemia/reperfusion injury (IRI) is the leading cause of early graft dysfunction and contributes to the shortage of donor liver grafts. However, despite its…
  • 2022 American Transplant Congress

    Epidemiology of Post Transplant Diabetes Mellitus

    S. Al Rasbi, I. Salmi

    Renal Medicine Department, The Royal Hospital, Bausher, Oman

    *Purpose: Diabetes mellitus (DM) is a common non-communicable disease and have serious metabolic complications that contribute to death, major cardiovascular events, organs failure, and increased…
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